This is the first commercially available , comprehensive genetic test for a
heart rhythm disorder. The FAMILION(TM) test is conducted at
Genaissance 's CLIA-approved laboratory located in New Haven, CT. Patients with untreated OSA are at higher risk for heart disease,
high blood pressure, stroke, memory problems, weight gain, impotency and
headaches .
Prospective patients can enter the contest by writing and submitting a
short essay explaining why they are in need of orthodontic treatment, along
with a photo showing their teeth.orthoclear .

musculoskeletal tmj

com.
Ventricular fibrillation, a rapid, irregular heartbeat affecting the lower
chambers of the heart, called the ventricles, can also occur. He earned
his medical degree at George Washington University School of Medicine and
completed his residency at the prestigious Cleveland Clinic Foundation . The company is encouraging people with
"unperfect" teeth to enter OrthoClear's "Win FREE Treatment " contest for a
chance to win complimentary OrthoClear treatment.

worn treat

familion. The
most common cause of obstructive sleep apnea (OSA) and snoring is due to a
blockage in the throat that prevents proper airflow, causing sufferers to wake
up hundreds of times throughout the night.
The Pillar Implant procedure is performed in the physician's office during
a single, short visit under local anesthesia . Dr. Essays will be judged on a number of
factors, including originality, creativity, and need for treatment.com.

headaches emitting

A patient's family members also benefit from the test because it can
identify if they inherited the same mutation as the initially symptomatic
patient and may be at risk of a potentially fatal arrhythmia.

About Genaissance
Genaissance Pharmaceuticals, Inc.

The Company's lead
therapeutic product, vilazodone for depression, is in Phase II of development . Oringher has been specializing in snoring and sleep disorders and
endoscopic sinus surgery for chronic sinusitis for 15 years.

grinds neck

(Nasdaq: GNSC), a leading developer and user of genetic
information to help guide medical therapy, said its DNA test, FAMILION(TM), is
on its way to becoming a key tool to help physicians save the lives of people
who are genetically predisposed to potentially fatal cardiac arrhythmias
caused by Long QT Syndrome (LQTS), Brugada Syndrome and related cardiac ion
channel diseases or channelopathies., Director of
the Long QT Syndrome Clinic and Sudden Death Genomics Laboratory at Mayo
Clinic.

musculoskeletal bruxism

Instead of waiting six to twelve months or more for
results of tests conducted in a research setting, doctors now obtain results
in as little as four to six weeks. During
ventricular fibrillation, blood flow to the body is reduced.
Dr. He has
accreditation from the American Academy of Otolaryngology-Head and Neck
Surgery, the American Rhinologic Society, the American Sleep Disorder
Association, and is a Fellow of the American College of Surgery. There are thousands of
OrthoClear doctors throughout the U.

teeth grindalert

Since its launch in late spring 2004, the FAMILION(TM ) Test has quickly
gained acceptance with over 130 patient referrals made by nearly 50 pediatric
and adult cardiologists and electrophysiologists., Ph. Genaissance also
markets its proprietary FAMILION (TM) Test, designed to detect mutations
responsible for causing Familial Long QT and Brugada Syndromes , two causes of
sudden cardiac death. Oringher and Feldman Oringher
Dettelbach Mesick Schoenfeld Otolaryngology, call (301) 652-8847 or visit us
at http://www.orthoclear.

purchased pain

These specialists utilize
the test as a vital component in their evaluation and management of patients
with symptoms of inherited Long QT Syndrome and other ion channel
abnormalities that, if left undetected, can cause sudden cardiac death. In nearly 80 percent of patients suffering from sleep apnea and
snoring the soft palate is believed to be the site of obstruction, causing
this serious problem. Doctors and prospective
patients who would like to learn more about OrthoClear may visit the company's
website at http://www.

neck grindalert

Genaissance Pharmaceuticals' New DNA Test - FAMILION(TM) - Becoming Key Tool for Detecting Long QT Syndrome a Potentially Fatal Cardiac Disorder

If a genetic mutation is
detected, its type and location can assist the physician in making treatment
selections that could include life -style modification, prescription or
avoidance of specific classes of drugs or the implantation of a defibrillator. and other countries relating to the five cardiac ion channel genes
examined by the FAMILION(TM) Test.

More information regarding the FAMILION(TM) Test can be found at
http: //www.
Brugada Syndrome is very similar to LQTS, however, the characteristic ECG
finding is different.
Left untreated, this condition has a serious impact on the long-term health of
sufferers . Oringher joined Feldman Oringher Dettelbach Mesick Schoenfeld
Otolaryngology in 1991 and is dedicated to providing patients with safe,
efficacious treatments for snoring and sleep disorders.

Find links to sites offering products that assist in treating Temporomandibular Joint Syndrome (TMJ).

neck screening

Most of the deaths can be
prevented with early diagnosis and treatment of LQTS. Genaissance disclaims any obligation to update any
forward-looking statement.

The contest winner will be treated by a dental professional trained on
OrthoClear's revolutionary clear aligner system.
Entries must be submitted through OrthoClear's website, at
http://www.
The contest is open to individuals 18 years of age or older at time of
entry.

alarm screening

The Genaissance test helps clarify the diagnosis in
these patients by examining five cardiac ion channel genes for a mutation that
is likely to cause LQTS or Brugada Syndrome.com. The stiffening helps to prevent or lessen blockages of the
airway -- effectively treating snoring and/or sleep apnea.
469-643-6395

treating syndrome

"The FAMILION(TM) Test has had a successful launch as evidenced by its
steady growth, particularly in the second half of 2004 when Genaissance booked
over $200,000 of test revenue.
LQTS is a condition that impairs the electrical system of the heart. is developing innovative products based
on its proprietary pharmacogenomic technology and has a revenue-generating
business in DNA and pharmacogenomic products and services.
"Many complaints of daytime fatigue can be attributed to snoring and sleep
apnea," noted Dr.
Oringher's peers perennially vote him among WASHINGTONIAN Magazine's TOP
DOCTORS. Patients may choose
from three convenient locations: Chevy Chase and Germantown, Maryland and
Washington, DC.S.

pain musculoskeletal

NEW HAVEN, Conn.
Medicare and a significant number of major insurance companies now provide
coverage for the Genaissance test.D.S.
Please visit http: //www.

screening headaches

"This genetic test for cardiac ion channel mutations may remove
uncertainty for the patients, their families, and their physicians with
respect to establishing a diagnosis and can guide the physician in determining
the best treatment options," says Michael Ackerman, M. For some people , these symptoms only occur when
they are stressed or taking certain medications. If not
corrected , ventricular fibrillation can cause death.
For more information on Genaissance, visit our website at:
http://www.
Sleep apnea is defined as an interruption of breathing during sleep. With Pillar I'm able to
offer patients a one-time, in-office procedure that offers relief from the
effects of OSA and snoring. So patients can eat, brush, and floss
during treatment as they normally would ," said Keith Wolf, Director of
Marketing for OrthoClear.

foam syndrome

The Pillar inserts
are less than one inch long and made from a woven soft polyester material that
has been used for many years in implantable medical products. To learn more about Dr.com.

OrthoClear to Give Away One Beautiful Smile With Launch of 'Free Orthodontic Treatment' Contest

About OrthoClear:
OrthoClear is the world 's leading provider of next generation invisible
aligner treatment.

grinds musculoskeletal

At the current rate of receipt of four or more
test samples each week, along with the reimbursement obtained from a large
number of insurance providers, we believe that FAMILION(TM) revenues will
continue to grow significantly and contribute to our revenue goals for 2005,"
stated Kevin Rakin, President and CEO of Genaissance .
Genaissance has a patent estate of more than 50 issued and pending patents
in the U. People with LQTS have
hearts that look and sound normal but may have abnormal electrical activity
when examined with an ECG. Some people with LQTS have a normal ECG at rest
but experience abnormal responses under certain conditions.

This press release contains forward-looking statements, including
statements about the expected growth and development of Genaissance's
business, such as Genaissance 's ability to detect associations between
clinical outcomes and genetic variation, the ability to assess how genetic
variation can affect drug response, efforts to build a drug candidate
pipeline , the timing and outcome of its genetic testing programs, the timing
of its ability to enter into drug development collaborations with
pharmaceutical companies, the ability of Genaissance to apply its
technologies to the development, marketing and prescribing of drugs and
Genaissance's ability to detect associations between clinical outcomes and
genetic variation. He appears regularly on television and radio as an
expert on the topics of snoring, sleep, sleep apnea and sinusitis.
"Straight teeth are such an important part of a person's smile and overall
appearance. OrthoClear allows patients to straighten their teeth using
a series of clear, plastic, removable aligners.

alarm pain

For example,
these people may have an unusual response when they are startled, experience
emotional stress or engage in vigorous physical activities. Syncope (fainting) is the most common symptom. The Company's product development strategy is focused
on drug candidates with promising clinical profiles and finding genetic
markers to identify a responsive patient population.

DC Doctors Make Dream of a Good Night's Sleep a Reality With New Procedure

e-n-t.com.com for complete details and official rules.

Contact:
Tricia Hummel Seifert
OrthoClear, Inc.

purchased treat

Significant intellectual property
facilitating the FAMILION(TM) Test has been provided by the Mayo Clinic, and
Dr.
Symptoms of LQTS may include fainting, seizures, abnormal, very fast
heartbeats and even death. This strategy enables
Genaissance to leverage existing clinical data and, thus, reduce the costs and
risks associated with traditional drug development and increase the
probability of clinical success and commercialization .
The Pillar Implant procedure is designed to stiffen the soft palate in
order to aid air flow and prevent the obstruction. SAN FRANCISCO, OrthoClear, the maker of the "Next
Generation in Invisible Orthodontics," is looking to award one lucky person
free orthodontic treatment. The contest ends June 15, 2006 and the winner will be
announced on or around July 15, 2006.

temporomandibular foam

LQTS can be an
inherited or an acquired disorder. The forward-looking
statements contained herein represent the judgment of Genaissance as of the
date of this release. This new treatment offers patients a
simple, one -time, in-office alternative to surgery or life-long mask therapy. Most patients report that the
procedure is virtually painless and that they are able to resume normal
activities and diet the same day. The Pillar Implant procedure is the only
implantable treatment approved by the Food and Drug Administration (FDA) for
mild to moderate OSA.

grinding pillow

D. These relatives
often have ambiguous findings on an ECG, while the results of the FAMILION(TM)
Test can answer whether or not they carry the familial mutation.

Ackerman is a paid consultant and member of Genaissance Pharmaceuticals'
scientific advisory board . Such statements are subject to certain factors, risks and
uncertainties that may cause actual results , events and performance to differ
materially from those referred to in such statements, including , but not
limited to, the extent to which genetic markers (haplotypes) are predictive of
clinical outcomes and drug efficacy and safety, the attraction of new business
and strategic partners, the adoption of our technologies by the pharmaceutical
industry, the acceptance of our cardiac tests by health care providers, the
timing and success of clinical trials, competition from pharmaceutical ,
biotechnology and diagnostics companies, the strength of our intellectual
property rights and those risks identified in our Quarterly Report on Form 10-
Q for the quarter ended September 30, 2004, filed with the Securities and
Exchange Commission on November 15, 2004, and in other filings we make with
the Securities and Exchange Commission from time to time. Oringher. During the procedure , the
physician places three inserts in the patient's soft palate, causing the
palate to stiffen . Not only are OrthoClear plastic aligners
virtually clear, but they're removable.orthoclear.

treating temporomandibular

The diagnosis of LQTS and other channelopathies by an electrocardiogram
(ECG) is often difficult and may be missed, which leaves a patient at risk for
sudden cardiac death.

Sudden Cardiac Death
Long QT and Brugada Syndromes, two types of cardiac channelopathies, are
disorders that are typically discovered in the first four decades of life and
can be fatal if not diagnosed and treated appropriately. Pillar(R) Implant Procedure Provides Low-Risk Treatment
for Snoring and Sleep Apnea - in One Office Visit

WASHINGTON, The practice of Feldman Oringher
Dettelbach Mesick Schoenfeld Otolaryngology, PC is pleased to announce it is
now accepting patients for a breakthrough treatment for snoring and sleep
apnea, the Pillar(R) Implant procedure .
Dr.

facial grinds

, Genaissance
Pharmaceuticals, Inc.genaissance. I sought a different
treatment and found a safe and effective way to address sleep apnea and
snoring problems with the Pillar Implant procedure."
The best-known symptoms of sleep apnea are snoring and daytime fatigue. He also consistently ranks very high among leading DC metro area
physicians in the Washington Consumers' CHECKBOOK, an unbiased non-profit
consumer ratings service. Each aligner is worn for 3
weeks , and can be removed to eat, brush, and floss, allowing patients to
maintain optimal oral health during treatment.

temporomandibular tmj

For many people it's the first thing they notice about others. The odds of winning are determined by the number of entries received.

claim alarm

tmj treating

"But most OSA patients are reluctant to wear a
CPAP mask at night or to undergo major surgery.
What makes OrthoClear so exciting is that it has given thousands of people the
opportunity to straighten their teeth, with minimal inconvenience or effect on
their lifestyle during treatment.