CanadianPharmacy doing business at http://www. http://www.
(NYSE: KG) announced today positive results from a clinical study evaluating
the effect of co-administration of intranasal PT-141 and Viagra in patients
with erectile dysfunction (ED).

Current
literature indicates that about 40% of all patients who receive an initial
prescription for a PDE-5 inhibitor do not renew the prescription due chiefly
to adverse side effects, drug interaction issues, and/or the lack of an
acceptable level of response.

About Erectile Dysfunction (ED)
ED is defined as the consistent inability to attain and maintain an
erection sufficient for sexual intercourse. to jointly develop and
commercialize PT-141. For further information, visit the Palatin web
site at http://www.

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announced today the companies are
filing parallel lawsuits against two international pharmacy spam rings
operating websites that sell illegal "generic" versions of Pfizer's erectile
dysfunction (ED) medication.
Consumers can visit http://www.com
2. http://www. http://www. It is estimated that 50% of all men over the age of 40
suffer from ED.com

About King Pharmaceuticals
King, headquartered in Bristol, Tennessee, is a vertically integrated
branded pharmaceutical company.

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Working together, the companies'
investigators uncovered a highly sophisticated spam ring with several groups
of affiliates all advertising websites associated with CanadianPharmacy. Once the
consumers' online orders are received on computers in New York, they are sent
to a call center headquartered in Canada, and then on to India for processing .S. Microsoft's lawsuits allege that the
pharmacy spammers sent email with deceptive and misleading information in
violation of the federal CAN-SPAM Act and other federal and state laws. Virtual RX
3.

About Viagra
Viagra(R) (sildenafil citrate) is a prescription medication indicated for
the treatment of ED.
The duration of erectile activity measured after co-administration of each
combination of PT-141 was significantly enhanced compared to that observed
with the relevant dose of Viagra alone. About 150 million men worldwide and 30 million American men
suffer from ED . Securities and Exchange Commission.

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S. "Pfizer is joining with Microsoft on these actions as part of our
shared pledge to reduce the sale of these products and to fight the senders of
unsolicited email that overwhelm people's inboxes. Leading businesses are
teaming up, pooling resources and sharing investigative information to stop
this illegal activity at the source," said Brad Smith, Senior Vice President
and General Counsel, Microsoft.com
6.org

Overview of Microsoft 's Legal Action
Microsoft filed two suits against the spammers promoting CanadianPharmacy
and E-Pharmacy Direct, in conjunction with Pfizer's suits against the
operators of these online pharmacies . Microsoft will
issue subpoenas to ISPs and other companies to identify and locate the
spammers . Co-administration of PT-141 and Viagra did not result in
any serious or significant adverse events .

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Viagra(R) (sildenafil citrate) is estimated to account for up to one out
of four spam messages. The
complaints also allege that the defendants are selling and importing non-FDA
approved sildenafil citrate in violation of U.cheapviagrastore. Viagra is available only from health care providers and
should always be used in accordance with its approved labeling.
Although the current ED market is primarily served by PDE-5 inhibitors
which target the vascular system, a substantial unmet medical need for
alternative sexual dysfunction therapies exists. Some important factors which may cause results to
differ materially from such forward-looking statements include dependence on
the companies' abilities to carry out their respective business plans;
dependence on the successful development and commercial acceptance of PT-141;
dependence on the companies' abilities to fund development of PT-141;
dependence on whether a commercial product results from PT-141 development
activities; dependence on the companies' abilities to establish and
successfully complete clinical trials necessary for approval of PT-141 as a
treatment for sexual dysfunction; dependence on the companies' abilities to
successfully collaborate in the development and commercialization of PT-141;
dependence on the availability and cost of raw materials; dependence on the
unpredictability of the duration and results of the U. Food and Drug
Administration's ("FDA") review of Investigational New Drug Applications
("IND"), New Drug Applications ("NDA"), and supplemental New Drug
Applications , ("sNDA") and/or the review of other regulatory agencies
worldwide; dependence on compliance with FDA and other government regulations
that relate to King's and Palatin's respective businesses; dependence on
King's and Palatin's abilities to successfully manufacture PT-141; and
dependence on changes in general economic and business conditions; changes in
current pricing levels; changes in federal and state laws and regulations;
changes in competition; unexpected changes in technologies and technological
advances; and manufacturing capacity constraints.

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NEW YORK, Pfizer, the maker of Viagra(R)
(sildenafil citrate) and Microsoft Corp.viagra.3
[range: 1. Palatin's patented drug discovery platform , MIDAS(TM),
streamlines the drug design process with an efficient approach to identifying
lead compounds from proteins.

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"As the maker of Viagra, the market leader in erectile dysfunction, Pfizer
is committed to protecting the public from health and other risks associated
with the illegal sale of fake and unapproved generic products claiming to be
Viagra," said Jeff Kindler, Executive Vice President and General Counsel at
Pfizer.
The orders are filled with illegal, unregulated and unapproved products.myepharmacydirect.J.
Palatin Technologies, Inc.

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Pfizer also filed ten other domain name actions.
In conjunction with Pfizer's suits against CanadianPharmacy and E -Pharmacy
Direct, Microsoft filed civil actions against the spammers advertising for
those websites . The
illegal generic drugs are then shipped from India to the United States and
delivered by an airfreight forwarding company based in the United States. These illegal drugs may be
contaminated , stored improperly, outdated, may not work as claimed, contain
potentially dangerous ingredients or may have no effect at all.com to learn more about how to
safely purchase ED products from legitimate online pharmacies.
Additionally, ten Uniform Domain Name Dispute Resolution Policy (UDRP)
actions were filed against heavily trafficked sites to seize domain names
allegedly using Pfizer's Viagra trademark in an unauthorized manner. All
allege that the respondents are using the Viagra mark in bad faith to promote
the sale of products that have not been approved by the U.sameasviagra. EzyDrugStore . The company offers a wide range of products and services designed
to empower people through great software -- any time, any place and on any
device. Viagra is
contraindicated in patients who use nitrates in any form at any time.
Patients should discuss their general health status with their doctors to
ensure that they are healthy enough to engage in sexual activity. In these patients , physicians should prescribe
Viagra with caution. (Amex: PTN) and King Pharmaceuticals, Inc.
Dr.S.

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Many of these
websites are registered with the true names and addresses of persons
unassociated with the websites or spam rings, and who were unaware that their
identities are being used in conjunction with these activities. This clinical effect was statistically significant in 3
of the 4 comparisons .

Forward-looking Statements
This release contains forward-looking statements within the meaning of
Section 27A of the Securities Act of 1933, Section 21E of the Securities
Exchange Act of 1934 and as that term is defined in the Private Securities
Litigation Reform Act of 1995.

These forward-looking statements reflect
managements' current views of future events and operations , including, but not
limited to, statements pertaining to the potential development and
commercialization of PT-141. The
companies do not undertake to publicly update or revise any of their forward-
looking statements even if experience or future changes show that the
indicated results or events will not be realized.

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com.cndpharmacy.com
3., and BRISTOL, Tenn. Additionally, the results of this study support the proposed
mechanism of action for PT-141. (Amex: PTN) is a biopharmaceutical company
focused on discovering and developing melanocortin (MC)-based therapeutics.
The Company is currently conducting clinical trials with its lead drug
candidate, PT-141, an MC receptor agonist, for the treatment of male and
female sexual dysfunction.

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Pfizer and Microsoft Target Sellers of Illegal Viagra and International Spam Rings

law, including the Federal
Food, Drug and Cosmetic Act. E-Pharmacy Direct doing business at http://www.

Microsoft filed three additional suits against spammers promoting the
following online pharmacies:

1.
Please see full prescribing information for Viagra (25 mg, 50 mg, 100 mg)
tablets at http://www. On average, the co-administration of
PT -141 and Viagra increased erectile activity duration by a factor of 5."

About PT-141
PT-141 is the first compound in a new drug class called melanocortin
receptor agonists under development to treat sexual dysfunction. For example, PDE-5
inhibitors are contraindicated in patients taking nitrates, primarily for the
treatment of cardiovascular disease.

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The defendants
allegedly use illegal and deceptive e-mail techniques that violate the federal
CAN-SPAM Act of 2003 and other state and federal laws.

Overview of Pfizer's Legal Action
The two lawsuits allege unlawful conduct involving trademark infringement
and dilution and unfair competition under both federal and state law as well
as deceptive trade practices in violation of New York state law.com

The identities of the individuals controlling the sites are unknown and
are therefore referred to in the complaints as "John Does.about-viagra-kamagra.com
5. http://www.freeviagraclub.viagra -123. DiscountRX
2.9 - 8. We
anticipate that the nasal formulation of PT-141 currently under development
will be as convenient as oral treatments and more patient-friendly than
invasive treatments for ED, such as injections and trans-urethral pellets. Based on early clinical data, we believe
that PT-141 should not be contraindicated in patients taking nitrates. The condition is correlated with
increasing age, cardiovascular disease, hypertension, diabetes, hyperlipidemia
and smoking.

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FDA.com
9. http://www. If patients
experience pain, nausea, or any other discomfort during sex, or an erection
that lasts longer than four hours, they should seek medical help.
Patients with recent serious cardiovascular events, hypotension or
uncontrolled hypertension or retinitis pigmentosa did not participate in pre-
approval clinical trials.5 mg or
10 mg). In addition, certain prescription drugs and psychogenic issues
may contribute to ED.palatin.

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The two companies have filed a total of 17 new actions against defendants
involved in the sale and advertising of potentially dangerous medications . Purchasing illegal generic "Viagra" can pose safety and financial risks
to consumers.
Because of the deceptive techniques employed by the defendants to mask their
true identities, Microsoft's suits name "John Doe" defendants.

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The
spam directs recipients to one of dozens of identical websites .

Pfizer Inc is filing lawsuits against the following two entities:

1. http: //www.shopviagra. http://www. King, an S+P 500 Index company, seeks to
capitalize on opportunities in the pharmaceutical industry through the
development, including through in-licensing arrangements and acquisitions, of
novel branded prescription pharmaceutical products in attractive markets and
the strategic acquisition of branded products that can benefit from focused
promotion and marketing and product life-cycle management.

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" Subpoenas
directed to various ISPs and other companies will help ascertain their true
identities.S.bioviagra.viagra-price-guide. The use of Viagra offers no protection against sexually
transmitted diseases, including human immunodeficiency virus (HIV).

Pfizer Inc discovers, develops, manufactures and markets leading
prescription medications for humans and animals and many of the world's best-
known consumer products.

Palatin Technologies and King Pharmaceuticals Report Positive Data from Clinical Trial Evaluating Co-administration of PT -141 and Viagra(R)

Doses of either 50 mg or 100 mg Viagra
were administered to thirty-two ED patients with or without PT-141 (7. It
also appears to result in a rapid onset of action. Other important factors
that may cause actual results to differ materially from the forward-looking
statements are discussed in the "Risk Factors" section and other sections of
King's Form 10-K for the year ended December 31, 2004 and Form 10-Q for the
second quarter ended September 30, 2004, and Palatin's Form 10-K for the year
ended June 30, 2004 and Form 10-Q for the first quarter ended September 30,
2004 , which are on file with the U.

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Pfizer has filed civil actions against two websites that allegedly promote and
sell products that are unapproved by the U. Consumers
place orders for drugs advertised as Viagra(R) (sildenafil citrate) or illegal
"generic" Viagra on one of several websites advertised by spam.half-price-viagra.com

About Microsoft
Founded in 1975, Microsoft (Nasdaq "MSFT") is the worldwide leader in
software, services and Internet technologies for personal and business
computing.com

,
Palatin Technologies, Inc.

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In addition, Microsoft filed three suits against spammers who
advertise other online pharmacies known under a variety of names, such as
"Discount RX," "Virtual RX," and "EzyDrugStore.com
4.net
10. Viagra has
been approved by regulatory authorities in more than 123 countries around the
world and is among the most widely prescribed medications, with more than 130
million prescriptions written for 23 million men worldwide . The co-administration of PT-
141 and Viagra may constitute an important treatment alternative for ED
patients in whom higher doses of a single therapy are not effective or are not
well-tolerated .

About Palatin Technologies, Inc.

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com

2.freegenericviagra.com
8. Less commonly, bluish vision,
blurred vision or sensitivity to light may briefly occur. CRANBURY, N .3]. In August 2004, Palatin entered into a strategic
collaboration agreement with King Pharmaceuticals , Inc.

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" Together, these pharmacy
spam rings have allegedly sent hundreds of millions of e-mail messages to
Microsoft's MSN Hotmail customers within the past year alone. Tracing the
order process, investigators determined that the website encompasses an
allegedly illegal pharmaceutical supply chain that spans the globe. NeutroSpec is
marketed and distributed by Palatin's strategic collaboration partner,
Mallinckrodt Imaging, a business unit of Tyco Healthcare.

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"
"The collaboration between Pfizer and Microsoft is another wake-up call to
those who abuse the Internet for illegal purposes. "At Microsoft we are combating this problem
every way we can, including legal action, to ensure our consumers are
protected from fraud."
Pfizer and Microsoft first investigated CanadianPharmacy, a website
advertised by high volume spamming. http://www. http://www. Clinical data indicates that PT-141 may be
effective in treating a broad range of patients suffering from ED.
NeutroSpec(TM), the Company's proprietary radiolabeled monoclonal antibody
product for imaging and diagnosing infections, has been approved by the FDA as
an imaging agent for the diagnosis of equivocal appendicitis.S.

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Food and Drug Administration
(FDA). These products may be manufactured in unregulated factories or
back rooms that do not adhere to the same rigorous standards for
pharmaceutical manufacturing required by the FDA.

1. http://www.

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The legal actions are the result of a seven-month
investigation during which the two industry leaders collaborated to track down
the illegal drug distributors operating these websites as well as the spammers
advertising them. The observations in this
clinical study are consistent with the co-administration of PT-141 and Viagra
producing an additive effect for the ED patient. This new
chemical entity is being evaluated in Phase 2 clinical trials studying the
efficacy and safety profile of varying doses of this novel compound in men
experiencing erectile dysfunction ("ED") and women experiencing female sexual
dysfunction ("FSD").

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viagra.
The purpose of this study was to evaluate the potential additive effect of
treating ED patients with both PT-141, which initiates erections via a central
nervous system mechanism of action, and Viagra, a peripheral vasodilator
indicated for erectile dysfunction. Each patient's erectile activity was monitored for 6 hours using a
RigiScan(TM) device in the absence of visual sexual stimulation. Importantly, the co-administration of PT-141 with up to 100 mg of
Viagra did not indicate any safety concerns. The mechanism of action of PT-141 may offer important
benefits over currently available products for the treatment of ED because it
appears to act on the pathway that controls sexual function without acting
directly on the vascular system.

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Many of these spam messages link to illegal websites
that promote "Viagra " and then send the consumer an illegal version of the
drug.com
7.
The most common side effects of Viagra(R) (sildenafil citrate) are
headache, facial flushing and upset stomach.
Discovered and developed by Pfizer, Viagra is the breakthrough oral
treatment for erectile dysfunction that is found to be effective and well
tolerated in more than 130 completed and ongoing clinical studies. Carl Spana, President and Chief Executive Officer of Palatin, stated,
"This study is part of our program to evaluate all potential indications for
PT-141.