It also offloads many routine, repetitive tasks from the
statisticians who can now focus on more rewarding analysis work.
The company maintains U. The improved heat map
visualization in DecisionSite 8. Over 25 ,000 users in close to 1,000
organizations around the world use Spotfire DecisionSite to drive
confident decision-making by quickly and easily spotting trends,
outliers and unanticipated relationships in critical business data.
"Many of our biotech and pharmaceutical customers who rely
entirely on SAS software will now have better access to the
cutting-edge graphical and statistical analysis methods available in
S-PLUS, from within a SAS environment," says Hopkins.
And, simple and affordable perpetual licensing policies help lower
the total cost of ownership. For more information, visit
info@insightful. You should not unduly rely on these forward-looking
statements which apply only as of the date of this release.

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DecisionSite 8.1, users can re-use stored
procedures for advanced query and for database write back. More information is available at:
http://www. These presentations , titled
"Developing, Testing, and Deploying Spotfire Guides by Biologists"
(featuring Maryann Whitley Ph.

Insightful Announces S-PLUS Clinical Pack for SAS Software Users

, president of PharmaStat , a
drug development and consulting services company specializing in
biostatistics, clinical programming , and data management.

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----

DecisionSite Computation Services Bring Leading Statistics
Packages into one Interactive, Visual Analysis Environment for Experts
and Non-Experts

Spotfire, Inc . This allows organizations to take better advantage of the
significant investment they have made in these computational and
modeling tools by packaging them in a business context and sharing
their value with other users across the organization.
"Traditionally, statistical analysis tools have been restricted to
use by experts," said Christopher Ahlberg, Ph.1 features greater flexibility and higher
performance in accessing data from a wide range of research
applications and data sources, allowing researchers from various parts
of the organization to take advantage of DecisionSite's powerful
visual data analysis for any and very large data sets. Now, scientists can view and
interactively manipulate hundreds of curves at once, and determine
compound behaviors at a glance. The resulting column
names from pivoting categorical columns into multiple ones are
configurable on a system level and editable on the information link
level.
On March 17th, Spotfire will host a Web cast for developers
outlining this new functionality and other new features in
DecisionSite 8. Now,
users are offered a free software tool that can import and merge
instrument data and experimental parameters directly into DecisionSite
8."
"The S-PLUS Clinical Pack is a great facilitator for interaction
between groups of SAS software users and S-PLUS programmers and
statisticians," says Alan Hopkins, Ph.D.

Setup and training from Insightful professional services.

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1 supports dynamic
curve fitting in individual or trellised scatter plots using linear,
polynomial, power, logarithmic, exponential, and basic IC50 curves as
part of its standard product offered to all customers under
maintenance. When
communicating insights from a dataset with many columns, such as
experimental results from micro arrays, it is important to get a high
level view of many different columns.1.cfm

Overcoming Data Analysis Bottlenecks

Spotfire launched its Instrumentation Partner Program in the
summer of 2004 aimed at helping researchers overcome data analysis
bottlenecks by enabling users of DecisionSite to directly access the
high volumes of instrumentation data for immediate analysis.

About Spotfire

Spotfire, Inc.com

S-PLUS graphical analyses augment
the "tables and listings" produced using SAS software, allowing
statisticians, clinicians, marketing, and other associates to more
quickly and comprehensively review clinical study results.

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1 is faster, and
supports analyzing very large data sets.

ABOUT INSIGHTFUL

Insightful Corporation (Nasdaq:IFUL) provides enterprises with
scalable data analysis solutions that drive better decisions faster by
revealing patterns , trends, and relationships.

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Currently, eight of the top 10 pharmaceutical companies employ
Spotfire 's DecisionSite analytic applications across their entire
spectrum of research operations.D.1, the latest version of Spotfire's visual data
analytics platform.

An End-to-End Life Sciences Research and Development Analysis
Environment

DecisionSite is now the analytics platform standard for eight of
the world's top 10 pharmaceutical research companies, and continues to
gain traction with leading life sciences organizations based on its
breadth of applications and ease of use. Providing direct access to the high volumes of
instrumentation data clears a major research hurdle for drug discovery
organizations. Statisticians and clinical
programmers can use the S-PLUS Clinical Pack to create modern S-PLUS
statistical and graphical analyses rapidly from within SAS software,
without any specialized training.
Designed to tightly integrate with Microsoft(R) Office, RTF and Web
technologies , the S-PLUS Clinical Pack can enhance communication and
facilitate report automation.
Comprehensive session, data, and job information is detailed
in the integrated SAS and S -PLUS log and output files, in
accordance with regulatory audit trail requirements.

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As
part of this ongoing effort, Spotfire is developing additional
integrations with the leading informatics data processing packages. (http://www. As the pharmaceutical industry faces increasing
pressure in areas such as drug safety, Spotfire DecisionSite has
emerged as a product that addresses all key business processes in life
sciences. Interactive curves are easy to set up and dynamically
respond and update as users filter their experimental data., and
European headquarters in Goteborg, Sweden . "Breaking down
technology barriers between these two excellent analytical systems is
in the best interest of good statistical practice. assessing recruitment sub-populations (such as
severity balance), outlier identification, lab measurement
summaries, and sub-group analysis.

A collection of macros for calling the functions in the S-PLUS
Graphics Library and managing the SAS environment from an
S-PLUS graphics perspective.

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spotfire. An example of an action can be for the end
users to tag bad-quality data directly in the database.spotfire. The S-PLUS Clinical Pack is set up through
stand-alone desktop, concurrent user, or server-based implementations,
typically in the context of structured development and production
environments. The macros provide a simple
harness for calls to the S-PLUS functions, and allow graphics
and analytics summaries to be output to prescribed locations
and/or incorporated within SAS ODS reports. Inaccurate assumptions
and known and unknown risks and uncertainties can affect the accuracy
of forward-looking statements.

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, a market leader in interactive, visual analytic
applications for business decision-making , has further opened
DecisionSite, its easy-to-use visual analytics application, to enable
decision makers at life science organizations to deploy statistical
tools written in SAS, Insightful S-PLUS , and R Open Source directly
within the DecisionSite application. provides interactive, visual data analytics
applications and services that empower enterprises and their end-users
to improve operational performance and gain an information advantage
over the competition. headquarters in Somerville, Mass .spotfire.

Business Editors/Technology Writers/Health Writers

SEATTLE----

New Clinical Data Analysis and Reporting Solution Provides
Rich Graphics, Modern Analytics in Validated Enterprise Environments

Insightful Corporation (Nasdaq:IFUL), a leading provider of
software solutions for analysis of numeric and text data, announced
today the release of an S-PLUS(R) Clinical Pack for SAS(R) software
users. The company has
been delivering industry-leading, high-ROI solutions to thousands of
companies in financial services, life sciences, biotechnology,
telecommunications , manufacturing, plus government and research
institutions.

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The open Computation Services
framework within DecisionSite will be used by Spotfire and partners to
build additional integrations with other pervasive life sciences
applications from SciTegic(TM), Inforsense(TM), MatLab(TM) and even
Excel (TM).

Spotfire Extends Leadership in Analytics for Life Sciences

"Using this innovative solution , we have better access to the
cutting-edge graphical and statistical analysis methods of S-PLUS,
from within the SAS environment," Foit says. Insightful consulting services provide
specialized expertise and proven processes for the design,
development, and deployment of customized solutions . Actual results could differ materially
from those expressed or implied by the forward-looking statements for
a number of reasons, including, without limitation, the risks
associated with errors or defects in our software and the risks
associated with market demand and customer acceptance of our products .

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1 offers
pharmaceutical and biopharmaceutical users an end-to-end analysis
environment for fast and effective analysis throughout the drug
discovery process.
Stored Procedures - In DecisionSite 8.
The company maintains U. (R) indicates USA registration.
Forward-looking statements are based on the judgment and opinions of
management at the time the statements are made.

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DecisionSite Posters allows researchers to share results - from
gene expression dendograms to drug safety signal detection - in one
online application that now supports heat maps, bar charts, pie
charts, trellising and text search.

Note to Investors - Forward Looking Statements

This press release contains forward-looking statements, including
statements about capabilities of our S-PLUS Clinical Pack and other
software and our ability to meet the needs of our customers.

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1 Product Release

Spotfire (R), Inc.
For those researchers looking to easily share results, Spotfire is
introducing new functionality in a significant upgrade to
DecisionSite's Web-based analysis and communication product:
DecisionSite Posters.
"As a company focused on pioneering new approaches for the
understanding and treatment of complex diseases, the ability to
understand the intricate relationships in data is a necessity ," said
Bill Ladd, Vice President of Discovery Systems at Genstruct, Inc., Leader of Expression Profiling
Informatics for Wyeth) and "Developing DecisionSite Guides and Tools
for a Dynamic User Environment " (featuring Christopher Savage,
Associate Systems Analyst, Merck) are complimentary at:
http: //www.1, resulting in better quality assurance and control for
researchers. "With this solution, we
are better able to synthesize and deliver client information essential
for decision-making at critical development milestones.

Scripts for combing the log and output files so that entire
analyses on specific projects can be automated and/or
triggered by changes in data sources or environments, and
debugging based on automated keyword and error condition
checking of the log/output files.

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As a result, Spotfire has made Computational Services an integral part
of the DecisionSite platform, allowing customers to utilize the power
of their preferred commercial or in-house statistics packages in
Spotfire's easy-to-use, interactive, visual analysis environment.spotfire. The upgrade puts more of DecisionSite's
interactive capabilities on the Web, allowing for wider sharing of
analysis results across researchers throughout the drug discovery
chain, including those users who do not use DecisionSite on a daily
basis. DecisionSite 8. Resulting column names are
easily configured to meet naming conventions. A whole new
work bench has been added to allow mapping of stored procedures for
data retrieval or for Action links that perform database actions
without retrieving data.com/solutions/life_sciences/ds81.

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In order for
researchers, statisticians and analysts to have real business impact,
the powerful capability of these tools must be deployed in an
application environment comprehensible to a broader number of business
users. Additional information can
be found at: http://www.spotfire.
"Combining S-PLUS and SAS software creates a powerful environment
for data management, exploratory analyses, statistical modeling, and
reporting ," says Darcy Foit, Information Services, manager, at New
York-based Cognigen Corporation, a provider of clinical data analysis
solutions and services in the pharmaceutical industry. product or service names are
registered trademarks or trademarks of SAS Institute Inc.

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com), a market leader in
visual analytics for business decision-making, has further extended
its leadership in the life sciences market with the closing of two
multi-million dollar enterprise license agreements with top 10
pharmaceutical companies, and the introduction of Spotfire
DecisionSite(TM) 8.1
offers the following improvements to its Information Services to
provide more flexibility in the data that can be accessed and the
performance and formatting in which it is delivered to the end-users.cfm

Best Practices Delivered by Major Pharma Leaders

As evidence of Spotfire's continuing momentum in life sciences,
the company recently completed Webcasts featuring top developers and
system architects from leading pharmaceutical companies, Wyeth and
Merck. Presenters discuss how they have integrated interactive, visual
data analytics from Spotfire into their research platforms, and
discuss the "how's and why's" of their implementation and the
resulting benefits to their companies.
The S-PLUS Clinical Pack is designed to incorporate the rich
graphics and modern analytics of S-PLUS within the SAS environment and
to enable life sciences companies to leverage the expertise of S-PLUS
statisticians across the enterprise . in the USA
and other countries.

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These statistical tools are often a source of real
competitive advantage but this knowledge is usable by only a select
few experts capable of running the statistical software."

Improvements to Information Services

In order to provide the best possible end-user analysis
environment, data access must be easy and fast.D. Additional information can
be found at: http://www.

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Spotfire Enables Life Science Organizations to Deploy Sophisticated Statistics across the Entire Research and Development Process

While Spotfire continues to expand its customer base to serve more
industries, the interactivity, ease-of-use and flexibility of
DecisionSite remain very popular with life science customers."

About Spotfire

Spotfire, Inc.
Insightful products include S-PLUS(R), Insightful Miner(TM),
S-PLUS(R) Server and InFact(R).

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That is our vision and that is how we are evolving
DecisionSite.----

Analytics Platform of Choice for Leading Pharmaceutical Companies
Gains Momentum with New Enterprise License Agreements and New
Capabilities in 8. When scientists are
looking at millions of compounds in a high-throughput screening
process, the ability to weed out bad compounds quickly is essential.
Microsoft is either a registered trademark or trademark of
Microsoft Corporation in the United States and/or other countries.

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"We
believe that every decision-maker in the organization can benefit from
fact-based decision-making , including the use of powerful statistics
packages. "The
new improvements in Spotfire 8.com/solutions /life_sciences/ds81.

The S-PLUS Clinical Pack includes:

S-PLUS Graphics Libraries comprising S-PLUS scripts that work
smoothly on SAS objects from within SAS software sessions.
S-PLUS and SAS output and (verbose) log files may be
integrated within directories or files for convenient access.com
SAS and all other SAS Institute Inc.

socr xpro

Across problem areas such as gene expression analysis, compound
library design, clinical analysis and even in marketing response
modeling and sales force deployment, pharmaceutical companies'
investment in data and tools has outpaced the researchers' and
analysts' ability to employ them quickly and effectively as part of a
business process.
While a variety of statistical functions are built into
DecisionSite and DecisionSite Statistics, many customers want to take
advantage of their own statistical models when doing complex analysis.
DecisionSite's unique Guided Analytics applications make it
possible for expert analysts to package and deploy statistical models
for the large majority of users who lack the statistics training
required to apply statistics to their business problems. With Guided
Analytics , the expert can capture a statistical algorithm within a
Guide - a series of step-by-step, scripted procedures - which allows
the use of sophisticated analysis by many more decision makers in an
organization .
DecisionSite 8. The
library includes the popular Trellis graphics that are
well-suited to a variety of aspects of clinical trial data
analysis, e.g.

S-PLUS offers enhanced procedures for batch processing
including verbose logging and creating output files and
methods for controlling these files and their components.
More detailed information regarding these and other factors that could
affect actual results is set forth in our filings with the Securities
and Exchange Commission, including our most recent Quarterly Report on
Form 10 -Q.

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S. The new version enables wider use of DecisionSite
across the R+D organization through faster , more flexible data access;
enhanced data analysis features, expanded results-sharing
capabilities , and improved security and administration.

S-PLUS XML libraries for input/output of XML.

robustness univariate

, CEO of Spotfire.
New visualizations allow for better data analysis for those users
who want to employ curve fitting and heat maps.
The new built-in interactive curve fitting provides users with
improved predictive analysis capabilities with an interactivity never
before seen in IC50 curve fitting. DecisionSite 8.
Pivoting - Pivoting data in DecisionSite 8.S. headquarters in Somerville, Mass. This
service allows organizations to extend and customize the
S-PLUS graphics libraries and the macro collection to their
particular needs, so that repetitive and/or important graphics
and analytics can be included in the framework for rapid
access by the group of SAS software programmers. We
undertake no obligation to update publicly any forward-looking
statements to reflect new information, events, or circumstances after
the date of this release or to reflect the occurrence of anticipated
events.

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Business Editors/Technology Editors

SOMERVILLE , Mass. Over 25,000 users in close to 1,000
organizations around the world use Spotfire DecisionSite to drive
confident decision-making by quickly and easily spotting trends,
outliers and unanticipated relationships in critical business data., and
European headquarters in Goteborg, Sweden.com

Business Editors

SOMERVILLE, Mass."
The S-PLUS Clinical Pack includes powerful S-PLUS graphical and
statistical analysis tools designed for easy access from inside the
SAS software environment. The company is a
leading supplier of software and services for statistical data
analysis , data mining and knowledge access enabling clients to gain
intelligence from numeric and text data .

anova multilog

1 provides overviews and the ability
to spot trends from many variables.1, such as interactive curve fitting
and improved heat maps, will allow us to make better data driven
decisions. provides interactive , visual data analytics
applications and services that empower enterprises and their end-users
to improve operational performance and gain an information advantage
over the competition.
Now SAS software users can access a comprehensive selection of
modern graphical and analytic methods to quickly and comprehensively
review clinical study results, identify potential safety issues, and
report results of clinical studies around their project teams. Some XSL style
sheets for converting between CDISC XML and S-PLUS XML are
available with the S-PLUS Clinical Pack, enabling CDISC I/O
from the S-PLUS environment.
Headquartered in Seattle, Insightful has offices in New York City,
North Carolina, France, Switzerland, and the United Kingdom, with
distributors around the world.

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Insightful Announces S-PLUS Clinical Pack for SAS Software Users

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Spotfire Extends Leadership in Analytics for Life Sciences

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variance recurrence

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Spotfire Enables Life Science Organizations to Deploy Sophisticated Statistics across the Entire Research and Development Process

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robustness univariate

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