"Maple is a cornerstone for my daily research and
to have an easy-to-use, Maple -based toolbox for projects such as
non-convex optimization and objective functions is ideal. Toolboxes target key application areas in engineering,
science and technical application development. and Alan R.

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com

ADVISORY/Young Scientists Display Research Projects at 2005 Massachusetts Science Fair

colloquium past

Maplesoft products embody the
most advanced and integrated technology for both numeric and symbolic
solution of complex problems. "We have some
of the finest speakers in their fields and attendees will be able to hear the
latest developments in the drug, device and diagnostic areas from a variety of
perspectives -- business, scientific and financial. Fair open to the public Saturday, May 7;
noon to 3:30 pm. MSSF, Inc.

cambridge calendars

Grace + Co.

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Maplesoft's Global Optimization Toolbox Penetrates Key Markets; Powerful Solution Brings Industrial-Class Optimization to Academic Commercial and Research App

Frequently, engineers and
researchers are forced to settle for solutions that are "good enough "
at the expense of extra time, money, and resources, because the best
solution has not been found ."
"The Global Optimization Toolbox has given me a new way to handle
the complex and difficult optimization problems in my operations
research projects," said Professor Mahmut Parlar, chair, Management
Science/Information Systems, DeGroote School of Business, McMaster
University, Canada."
"MichBio Expo 2005 will be both a great network and educational event,"
said Randal Charlton, CEO of Asterand and Chairman of MichBio.

foundations blc

Admission free.

WHERE: Johnson Athletic Center , MIT Campus, Cambridge, Mass.

algorithms newton

Designed to work seamlessly with the core Maple product suite, these
high-performance products deploy best-of-breed technology to deliver
maximum benefit from the world's most powerful technical software
platform. For more information,
visit http://www.

About Maplesoft

Maplesoft is a world leader in mathematical and analytical
software. Panel topics include: "Intellectual Property - Issues and
Impact on Drug Development," "Development of Medical Device Companies," "New
Business Growth and Development of Life Science Industry Companies ," "Applying
Michigan Automotive Industry Technology to the Life Sciences Industry," "The
Current State Of Fundraising and Life Science Entrepreneurial Activities in
Michigan," "Future Trends in the Pharmaceutical Industry: Outsourcing and In-
licensing to Feed the Development Pipeline" and the expo will close with the
dynamic discussion of "Stem Cell Research: Science, Bioethics and the
Political Debate in Michigan.

CAMBRIDGE, Mass.

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The
afternoon keynote features State of Michigan Senator, Valde Garcia. Prizes and scholarships to be awarded on
Saturday afternoon, May 7, beginning at 3:30 pm in Kresge Auditorium,
MIT.

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In addition to US-based organizations such as Fairchild
Semiconductor, Kentucky State University and Los Alamos National
Laboratory, the Global Optimization Toolbox is being used by
organizations in Japan, Korea, Germany, Italy and France, among
others.maplesoft. Over two million users at thousands of
organizations benefit from advanced Maple technology. Maplesoft's
commercial customer base includes Boeing, Bosch, Canon and NASA.

ANN ARBOR, Mich. See agenda details on the event at
http://www.5 million worth
of awards over the past 5 years, and is now in its seventh year of
allowing students to enter projects in the team division., Merck Research
Laboratories- Boston, and a number other Massachusetts companies,
professional organizations and individual donors. Visit
www.

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Released in June 2004, the Global Optimization
Toolbox extends the power of Maple(TM) 9. The finalists to the Pfizer Research Contract Competition will
also be presented on September 29th, contending contract and secured funding
with Pfizer. Guidelines and applications for the meetings and competition are
available at the website.. R.

science algorithms

"Full global
optimization is critical and Maple's optimization add-on is the only
software I have tried that even comes close to solving these
problems.
MichBio hosts the MichBio Expo 2005 with sponsorship from Pfizer Global
Research and Development, Michigan Economic Development Corporation, Asterand ,
Esperion, Van Andel Institute, Henry Ford Health System, Michigan State
University, University of Michigan, and Wayne State University., Genzyme Corporation, Novartis, INTEL Massachusetts,
Boston Scientific, W.

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MichBio Expo 2005 Announces Agenda

Education Editors/Science Editors
ADVISORY .

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Additionally, virtually every major university and research institute
in the world, including MIT, Stanford, Oxford and Waterloo, has
adopted Maple products to enhance their education and research
activities.michbio.

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Laurent
Bernardin, Maplesoft's Chief Scientist. For more information, visit www.
Awards Ceremony at 3:30 pm in Kresge Auditorium, MIT,
Cambridge, Mass.

conferences science

In engineering, constraints
may arise from technical issues. In business, constraints are related
to many factors, including cost, time and staff.5, the standard among
interactive mathematical software; MapleNet, a comprehensive
mathematical infrastructure for the Web; and Maple T.A.org/expo .

Meetings, conferences and symposia related to mathematical logic.

january session

Business Editors/High-Tech Editors

WATERLOO, Canada----Maplesoft(TM),
the leading provider of high-performance software tools for
engineering, science and mathematics, today announced the success of
its Global Optimization Toolbox in the academic, commercial and
research markets. "Using the Global Optimization
Toolbox , users can formulate optimization models easily inside the
powerful Maple numeric and symbolic system , and then use world-class
Maple numeric solvers to return the best answer, fast.
Panel Presentations -- The event includes panel presentations that will
provide attendees with an overview of cutting edge technologies in pharma and
medical devices.

july cambridge

5, the standard among
interactive math software , enabling a wide range of professionals to
obtain the mathematically optimized solution to complex modeling
problems.com/products/toolboxes or call
1-800-267-6583 ext 411 (US and Canada).

Principal
sponsors of the 2005 fair include EMC2 Corp.

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Keynotes + Panel sessions announced; Pfizer Research Competition and
Business Development Meetings round out the day's events .
Keynote Addresses -- The MichBio Expo 2005 kicks off with keynotes from
Lothar Krinke, PhD the Senior Director of BioSciences Technology Development
at Medtronic, Inc."
Other events that day include a full exhibition hall, showcasing more than
fifty of the area's most exciting life science leaders in finance, research,
and government.

About the Massachusetts Science Fair

The Massachusetts State Science Fair was founded by the American
Academy of Arts and Sciences and the Massachusetts Secondary Science
Educators in 1949, and has since hosted more than 17,000 students
throughout the Commonwealth.com

newton past

"The Global Optimization Toolbox meets the needs of industry
professionals by providing the tools they need to solve a wide range
of complex modeling problems, ranging from advanced engineering design
applications to econometrics and finance , management science, medical
research and biotechnology, and scientific modeling," said Dr.

mathematical calendars

"
"Maple's optimization add-on has permitted me to lock in on
optimal parameters in problems involving six parameters on a system
with three orders of magnitude for each dimension," said Ron Lenk,
systems applications engineering manager at Tyco Electronics and
author of Practical Design of Power Supplies . Its suite of products includes Maple 9. Saltiel, PhD, Research Professor and the
Director of the Life Sciences Institute at the University of Michigan. The fair has awarded $1. is
incorporated in Massachusetts as a not-for-profit corporation and is
Federal tax-exempt organization under Federal law 501 (c) (3).

july january

Optimization is the science of finding solutions that satisfy
complicated constraints and objectives.----Students from high
schools throughout the Commonwealth will exhibit their research
projects and compete for more than $300,000 in prizes and scholarships
at the 56th annual Massachusetts Science Fair, May 6 + 7, 2005 at
Johnson Athletic Center, MIT Campus, Cambridge, Mass.

logic isaac

maplesoft.
Early registration is available until August 29 at $100 for MichBio
members and $150 for non-members . Project judging
takes place Friday, May 6., The Cabot Corporation,
Biogen Idec, Inc.

science conferences

The goal of global
optimization is to find the absolute best answer for models that have
a number of possible solutions, a process that can be extremely
difficult without the best tools. The Global
Optimization Toolbox is a very valuable resource for anyone who deals
with nonlinear optimization problems in operations research,
engineering, economics or other applied sciences."
The Global Optimization Toolbox is part of the Maple Professional
Toolbox series of add-on products that greatly extend the scope and
functionality of Maplesoft products in specialized application areas., a system for
automated grading of mathematics tests. Its standards-compliant algorithms are
renowned for its speed, accuracy and reliability.

WHAT: 2005 Massachusetts Science Fair

WHEN: May 6 + 7, 2005.

cambridge esslli

In addition,
Maplesoft leads the market with innovations that make the management
of technical knowledge - whether in industry, or in a classroom - more
effective and efficient., The 5th annual MichBio Expo
announced its conference agenda for the nationally attended event scheduled
for Thursday , September 29th, at COBO Center in Detroit, Michigan.

session newton

Business Development Meetings are where MichBio members have
the opportunity to meet one-on-one for 25 minutes in a private setting with
development and procurement executives from national pharma and medical device
companies., Teradyne, Inc.scifair .