today announced the award of an 18-month Small Business Innovation Research
(SBIR)-Advanced Technology grant from the National Institute of Allergy and
Infectious Diseases (NIAID) of the National Institutes of Health (NIH) for the
testing of a novel vaccine ultimately directed against Human Immunodeficiency
Virus (HIV), the causative agent for Acquired Immunodeficiency Disease
Syndrome (AIDS) in humans . The studies are being conducted in collaboration
with Drs.

About Juvaris:
Juvaris BioTherapeutics was created in 2003 to develop an
immunotherapeutic product platform for the treatment of infectious diseases
and cancers using lipid-DNA complexes. Moreover, substantial immune responses have been
induced following oral and intranasal administration. This platform provides
the opportunity to develop many disease-specific immunotherapy products, for
which there are significant unmet medical needs.

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The JuvaVax(TM) vaccine is capable of
activating substantial antibody and cellular immune responses, particularly
cytotoxic T lymphocyte (CTL) activity, considered important for protection and
treatment of virus infections. Juvaris
appreciates the opportunity to demonstrate the power of its immunostimulation
technology through this grant and collaboration.

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The winning
educators will be given the professional experience of a lifetime. WorldStrides has provided a variety of
educational travel programs to more than two million elementary,
middle, and high school students since its inception in 1967. Cationic lipids are formulated with
non-coding DNA (plasmid) to create JuvImmune(TM), a lipid-DNA complex, which
as a single product will have utility in multiple cancer and infectious
disease applications.
On January 9, 2006, the Company announced the award of a two-year Small
Business Technology Transfer (STTR) grant from the NIAID for the development
of an Influenza A virus vaccine.

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"
Extraordinary teachers change a student's perception of the world.
The Company encourages investment and partnering inquiries, including this
project, and can be reached at its website @ http://www.

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C.

Company Contact:
Martin D.

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com/scienceaward and complete the online form. For more information about WorldStrides,
please visit www. The vaccine will initially be tested by the
CNPRC group in Rhesus macaque non-human primates to determine immune response
activation . "Juvaris is excited to collaborate
with the CNPRC in the evaluation of this vaccine approach in non-human
primates.

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Business Editors/Education Editors

CHARLOTTESVILLE, Va. Kristina Abel and Chris Miller at the California National Primate
Research Center (CNPRC), University of California , Davis.
This NIH-funded project involves the use of Juvaris' proprietary
JuvaVax(TM) vaccine platform containing an inactivated Simian Immunodeficiency
Virus (SIV) as a model for HIV.

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"We are pleased to be working on the development of a potential HIV/AIDS
vaccine candidate with the support of NIAID," said Martin D. Immunological responses elicited by the lipid-DNA
complexes have been successfully demonstrated in both prophylactic and
therapeutic settings in a variety of mammals including rodents, rabbits, cats,
dogs and non-human primates. Cleary
Juvaris BioTherapeutics , Inc.

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WorldStrides is the largest and most trusted student educational
travel company in the country.9 million new HIV infections and 3. Life expectancy has been severely impacted by AIDS
in sub-Saharan African countries, and is now beginning to impact India, China,
Russia, and Eastern Europe .

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4 million (~1 million, US) are currently living with the infection.

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----Portland
area teachers are encouraged to nominate outstanding science educators
that are currently instructing 7th and 8th grade science courses for a
new award from WorldStrides, an educational travel school., Orlando, Florida , Salt Lake City, Utah, New York, and
Williamsburg, Virginia.worldstrides.

Juvaris Announces Receiving NIH Grant Award for HIV Vaccine Development

Subsequent studies will evaluate vaccine-generated protection in
the SIV-infection monkey model, which is similar to HIV infection in humans.

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Nominations are being accepted now through May 6, 2005. As many
as 200,000 students in a given year have traveled with WorldStrides to
destinations throughout the United States and the world.
Demonstrated efficacy in this model will provide the basis for subsequent
HIV/AIDS vaccine development.
Approximately 4.

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When combined with disease-specific antigens, the technology creates
JuvaVax(TM) vaccines capable of activating substantial antibody- and
cell-mediated immune responses, particularly induction of cytotoxic T
lymphocytes (CTL).
925.

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Educators will snorkel with
manatees, experience a delicate ecosystem at Egmont Key, and Crystal
Springs Preserve, and study sharks with scientists at the Mote Marine
Lab, a world-leading shark research center. WorldStrides is headquartered in Charlottesville ,
Virginia, and has satellite offices in Reno, Nevada, Newport Beach,
California, San Jose, California , Marlton, New Jersey, Washington,
D.

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The JuvImmune(TM) product has been shown to be at least
50 -times more potent at triggering innate immune activation and interferon
release than current immune stimulants.

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marsupials mammalogy

Cleary,
Co-Founder, Chairman and CEO of Juvaris.

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WorldStrides Recognizes Portland Science Teachers with Science Teaching Award

com

PLEASANTON, Calif. We believe the various attributes of the JuvaVax(TM) platform
strongly support the requirements for an effective HIV vaccine .com.399.6200
mdcleary@juvaris.

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Winners will also receive the
Making a World of Difference all-expenses-paid trip to Florida to
experience what they teach everyday. Statistics from the World Health Organization-UNAIDS joint program on
the epidemic estimated in December 2004 that worldwide , more than 60 million
adults and children have been infected with HIV, 28 million have died of AIDS ,
and 39.juvaris.

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"
The need for a vaccine to prevent HIV infection and AIDS worldwide is
urgent .com

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Nominations
are being accepted for the Making a World of Difference Science
Teaching Award from the Portland area where five winners will be
formally recognized on May 16, 2005. "It is an honor to meet the educators that
dedicate their lives to enriching the knowledge of others . The
WorldStrides mission is "Enriching Students' Lives" by extending
education into the worldwide classroom and providing the best
opportunity for learning through seeing, experiencing, and
interacting .1 million AIDS-related
deaths occurred in 2004.

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"We are excited to recognize and reward exceptional science
teachers for their role in shaping students' futures," said Jim Hall,
CEO of WorldStrides .

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To nominate a science educator, visit
www.worldstrides., Juvaris BioTherapeutics, Inc.