Lowe's Makes Significant Voluntary Green Power Purchase

MOORESVILLE, N. Lowe's purchases the green power in the form of electricity generated
from biogas, solar, and wind resources from six different providers. That is comparable to removing nearly 2,000
cars from the road for one year or planting more than 3,000 acres of trees per
year.

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Partners in
the program switch to green power for a portion of their electricity needs in
return for EPA technical assistance and recognition . The Green Power
Partnership currently has more than 600 Partners, including Fortune 500
companies , states, federal agencies, trade associations, and universities.

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About the U.htm.2 billion , Lowe's Companies, Inc. is a
FORTUNE(R) 50 company that serves approximately 12 million customers a week at
more than 1,225 home improvement stores in 49 states.

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In the
event such risks or uncertainties materialize, Shire's results could be
materially affected.
(Logo: http://www.

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com. These renewable energy sources are
cleaner than traditional sources of electricity that produce carbon dioxide
(CO2), a greenhouse gas linked to global climate change. "Lowe's is leading by example and setting a standard for
environmental leadership for its peer institutions.

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18, 2006."
"The EPA applauds Lowe's for being among the largest retail purchasers of
green power," said Blaine Collision , program director of the EPA's Green Power
Partnership.

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, Lowe's announced today that it
has been named to the U. Green power
purchases support the development of new, renewable energy capacity.

About Lowe's
With fiscal year 2005 sales of $43.

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Shire Pharmaceuticals Group plc: Notification of Closing

Such forward-looking statements involve a number
of risks and uncertainties and are subject to change at any time.
"As one of the nation's largest green power retail purchasers, we are
proud to help drive demand toward more responsible energy generation," said
Michael Chenard, Lowe's director of environmental affairs. "When combined
with our efficient store design, Lowe's is helping conserve natural resources
and eliminate the production of greenhouse gases.

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The list highlights Green Power Partnership
retailers that have made the largest annual voluntary green power purchases
through Jan.
The U.gov/greenpower/.

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Shire has operations in the
world's key pharmaceutical markets (US, Canada , UK, France, Italy, Spain and
Germany) as well as a specialist drug delivery unit in the US.

EPA Recognizes Lowe's as One of Top Green Power Purchasers

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For more information, visit Lowes.

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shire.
For more information on EPA's Top 10 retail Partners list, visit:
http://www., the 60-year old company is the second-largest home improvement retailer
in the world.

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EPA's Green Power Partnership
The Green Power Partnership is a voluntary EPA program that seeks to
increase the use of green power among leading U. organizations.epa.

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newscom. EPA estimates that Lowe's green power purchase is equivalent to
preventing more than 22 million pounds of carbon dioxide (CO2), a greenhouse
gas linked to global warming.gov/greenpower/partners/top10retail. For a full listing of the
more than 600 EPA Green Power Partners and information about buying green
power, see the Partnership's Web site at http://www.

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The risks and uncertainties include, but are not limited
to, risks associated with the inherent uncertainty of pharmaceutical
research, product development, manufacturing and commercialization, the
impact of competitive products, including, but not limited to, the impact of
those on Shire's Attention Deficit and Hyperactivity Disorder (ADHD)
franchise, patents, including but not limited to, legal challenges relating
to Shire's ADHD franchise, government regulation and approval, including but
not limited to Health Canada's suspension of ADDERALL XR(R) sales in Canada
and the expected product approval dates of MTS (METHYPATCH) (ADHD), SPD503
(ADHD), SPD465 (ADHD ), SPD476 (ulcerative colitis), SPD480 (ulcerative
colitis) and NRP104 (ADHD), including its scheduling classification by the
Drug Enforcement Agency in the United States, Shire's ability to secure new
products for commercialization and/or development and other risks and
uncertainties detailed from time to time in Shire's filings with the
Securities and Exchange Commission, including its Annual Report on Form 10-K
for the year to December 31, 2004. Environmental Protection Agency's (EPA) list of Top
10 Retail Green Power Partners.C.

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"SAFE HARBOR" STATEMENT UNDER THE PRIVATE SECURITIES LITIGATION REFORM
ACT OF 1995
Statements included herein that are not historical facts are
forward-looking statements.com/cgi-bin/prnh/20031205/LOWLOGO)
Green power is electricity produced from renewable generation sources such
as biogas, solar and wind turbines.

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Lowe's was recognized for its voluntary purchase of green power for use at
stores and warehouses in North and South Carolina , New Mexico, Tennessee and
Texas. Based in Mooresville,
N.

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has successfully closed.

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Lowe's
remains the largest purchaser of green power in the Tennessee Valley Authority
(TVA) service area as well as North Carolina.

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BASINGSTOKE, England and PHILADELPHIA, Pennsylvania, Shire Pharmaceuticals Group plc (LSE: SHP, NASDAQ:
SHPGY, TSX: SHQ) today announced that the acquisition of Transkaryotic
Therapies Inc.
Notes to Editors
Shire Pharmaceuticals Group plc
Shire Pharmaceuticals Group plc (Shire) is a global specialty
pharmaceutical company with a strategic focus on meeting the needs of the
specialist physician and currently focuses on developing projects and
marketing products in the areas of central nervous system (CNS),
gastrointestinal (GI), and renal diseases .S.

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For further information on Shire, please visit the Company's website:
http://www.C.epa .