org . The understanding of how subtle genetic
variations contribute to disease risk, prognosis and drug response will lead
to new and more effective drugs, predictive diagnosis, and the ability to
better tailor therapies to individual patients.
All other trademarks and registered trademarks are the property of their
respective owners.

Support groups related to specific health diseases or disorders.

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In the majority of cases, the
cause is unknown. Leventhal, MD as Senior
Director of Medical Affairs, and Leslie Bunce, MD as Director of
Medical Affairs. He
was a career officer with the U. SNP selection in the
candidate genes utilized both a HapMap-based tagging-SNP approach and
amino-acid changing SNPs to maximize the informativeness of the panel.

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"I
wasn't going to let it. She then joined a global
CRO where she directed a wide variety of drug safety, medical writing
and medical monitoring activities for pharmaceutical and biotech
clients., ParAllele
BioScience, Inc. For the first time researchers can use a single assay to
conduct affordable, large-scale genetic studies in two important areas:
identifying the genes responsible for autoimmune diseases such as lupus,
multiple sclerosis and rheumatoid arthritis , and collecting information on
individual susceptibility to infectious disease or patient response to
immunization.
The Immune-Inflammation Panel is available this quarter through
ParAllele 's genotyping services and as a MegAllele(TM) Human
Immune-Inflammation Genotyping Kit, sold by Affymetrix .

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Epilepsy Foundation Salutes Steelers' Alan Faneca On Super Bowl Sunday


Faneca was diagnosed with epilepsy at age 15.C.
INC Research has offices in North America and Western, Eastern and
Central Europe. today announced collaborations with the University of
Southern California (USC) as well as the Baylor College of Medicine, to
perform large-scale genetic association studies of autoimmune and infectious
diseases respectively. "Both (Services and
Kits) can be cost-effectively combined with other standard or custom panels to
target population-specific or disease-specific genes that are not already
included in the off-the-shelf panel," said Clark Mason, PhD, Senior Director
Product Marketing, ParAllele.

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You can be yourself and
be open about it and move on and do what you're able to do.
In their new roles, both Drs.

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The company's investors include Abingworth Management , Index Ventures, Mohr
Davidow Ventures, and Versant Ventures.parallelebio.

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Now, at almost 30, the
five-time All-Pro player is widely regarded by football legends and experts as
one of the best offensive guards in the NFL. It is equal in prevalence to
cerebral palsy, multiple sclerosis and Parkinson's disease combined.epilepsyfoundation.
"We are enthusiastic about using ParAllele's Immune-Inflammation panel to
discover genetic markers for childhood onset Lupus. The Kit was developed in partnership with
Affymetrix to run on the, soon to be released, Affymetrix GCS 3000
MegAllele (TM) System.

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Why? It's because he
has become an inspiration to almost 3 million Americans living with epilepsy. "My parents instilled in me the importance of
telling people," he explained. - Immune-Inflammation panel enables the most comprehensive studies of
autoimmune and infectious diseases -

SOUTH SAN FRANCISCO, Calif.

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Seizures are caused by brief,
spontaneous disturbances in the brain's electrical activity. The episodes can
be traced to genetic abnormalities , head trauma, infectious diseases that
spread to the brain, and other conditions. For more information visit www.


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"

The Epilepsy Foundation, a national non-profit with affiliated
organizations throughout the United States, has led the fight against epilepsy
since 1968.
A former research physician who is board certified in neurology,
Dr. The new panel
will cover about 8,000 SNPs from over 1,000 candidate genes related to the
genetics of immunity and inflammation and is suitable for studies in multiple
ethnic populations.
ParAllele BioScience, Inc. is accelerating healthcare breakthroughs by
providing comprehensive genetic discovery solutions to the life science
research , pharmaceutical and diagnostic sectors.

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I was going to do everything normally. "Thanks to Faneca, people living with
epilepsy are finally seeing why epilepsy isn't a barrier to success. For additional information, please visit
http://www. We are excited about combining the Immune-Inflammation
panel with 1,500 of our custom SNPs to assay nearly 10,000 total SNPs.

About ParAllele BioScience , Inc.

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, The Pittsburgh Steelers are going to
the Super Bowl and - to many people with epilepsy and their families - all
eyes will be on Pittsburgh All-Pro Guard Alan Faneca.
Epilepsy is marked by recurring seizures. He served for over 13 years as Director of the Division
of Demyelinating Atrophic and Dementing Disorders, National Institute
of Neurological Disorders and Stroke (NINDS) within the NIH. Leventhal acted as a top consultant to pharmaceutical
and biotechnology companies and academic institutions developing
neurological compounds. They augment the
therapeutic experience and industry knowledge of our current clinical
team, in addition to bringing a tremendous depth of knowledge in the
area of government science policy and ethical considerations in
clinical research. This
will greatly increase the statistical power and gene coverage in our human
respiratory pathogen (flu) study," said John W. Headquartered in South San
Francisco, California, ParAllele BioScience was founded by a team of leading
researchers from the Stanford Genome Technology Center and Uppsala University .com.

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Dr.

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LANDOVER, Md.com


The company's products and
services utilize a multiplexed approach that leverages novel biochemical
processes rather than complex instrumentation to discover and analyze minute
variations in the human genome.

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Incorporating over 5
million genotypes, this will be the largest scale childhood onset Lupus trial
of its kind," said Dr. Jacob is a
leading expert in Lupus and has collected a large cohort of carefully
annotated samples from patients affected by this disease, and their family
members.

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INC Research Adds to Therapeutically Specialized Medical Affairs Team

incresearch. Chaim Oscar Jacob, MD, PhD, Associate Professor at the
University of Southern California Keck School of Medicine.

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"I honestly didn't let [epilepsy affect me]," Faneca said . Most
recently, Dr."
INC Research, through its dedicated INC Oncology(R) and INC CNS(R)
divisions , manages all aspects of global clinical development programs
for pharmaceutical and biotechnology companies developing treatments
targeting cancer and central nervous system disorders. Its
INC DataSpectrum(TM) division provides a full range of data
management, statistical analysis and medical writing services to
support global drug development requirements for any therapeutic area.

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Interviewed recently in EpilepsyUSA, Faneca discussed growing up with
epilepsy and how he was never going to let it keep him from playing the game
he loved. Public Health Service for over 32
years , serving in multiple director level positions within top U.S.
The MegAllele(TM) Immune-Inflammation panel will also enable a better
understanding of why patients respond differently to treatment for infection
by external pathogens. "We are pleased to extend our collaboration with
ParAllele to study the genetic basis of the variability in a patient's immune
response to vaccines.

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Epilepsy is the third most common neurological disorder in the United
States after Alzheimer's disease and stroke."
Faneca also discussed in the interview why he is so open about his
epilepsy, and where he garners his strength to speak freely about this
unfairly stigmatized condition. You don 't have to feel
inferior to your friends if that's how you're feeling.

Business Editors/Biotech Writers/Health Editors
BIOWIRE2K

RALEIGH, N.----INC Research(R), a
global contract research organization (CRO) specialized in central
nervous system (CNS), oncology and pediatric clinical research ,
announced today the appointment of Carl M. After completing a four-year combined clinical and
research Hematology fellowship at Strong Memorial Hospital in
Rochester, New York, she became an Assistant Professor at the
University of Rochester School of Medicine, where she attended on the
Hematology and Vascular Medicine services and performed basic research
as an NIH sponsored principal investigator .

ParAllele BioScience Collaborates With Both USC and Baylor on Large-Scale Association Studies of Lupus and Respiratory Pathogens

For more information about ParAllele,
please visit the company's website at: http://www.

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S. In addition,
INC Pediatrics(TM) offers specialized drug development services for
products to treat neonatal, pediatric and adolescent illnesses.

denville sarcoma

"
"We're big fans of Alan Faneca ," explained Tony Coelho, chair of the
Epilepsy Foundation.
government health agencies. His background includes roles at the Food
and Drug Administration as Deputy Director, Bureau of Drugs and
several divisional director positions at the National Institute of
Health (NIH). Bunce received her board certification in internal medicine
and hematology.
John Potthoff, PhD, President of Clinical Development for INC
Research states, "We are very pleased Drs. Belmont, MD, PhD, Director of
the Cardiovascular Clinic at Baylor College of Medicine.

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"It's very difficult for many people - especially celebrities - to admit
to living with this unfairly stigmatized condition, let alone a five-time All-
Pro football player," Coelho continued. Most recently, she served as a medical consultant on an
independent review board. This expertise allows us to further evolve the
exceptional level of support we can provide our customers in the
complex areas of CNS and oncology research. The collaboration with USC focuses on discovering the genes
associated with Lupus. The second collaboration, with Baylor , is one of the
first to measure the genetic basis of patient response to the flu vaccine.

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NOTE: ParAllele and MegAllele are trademarks of ParAllele BioScience,
Inc.

sarcoid autoimmune

"If you have a seizure and your family's not
around, people need to know what's going on with you. By being open, you
don 't have to feel like you're hiding something.
Dr. Leventhal and Bunce have
joined the INC Research Medical Affairs team.
Gene selection for this product was performed by scientists at ParAllele
in collaboration with researchers at USC and Baylor.

dysplasia sarcoid


Epilepsy is not a single entity but a family of more than 40 syndromes that
affect 50 million people worldwide. "We're tremendous fans of his , not only because of his
on-the-field heroics, but mostly because of his courage to speak candidly
about his own experience with epilepsy. The Foundation's goals are to ensure that people with seizures
are able to participate in all life experiences; and to prevent, control and
cure epilepsy through research, education, advocacy and services, so not
another moment is lost to seizures. Leventhal and Bunce will be pivotal
members of the INC Research Medical Affairs Team, providing
specialized therapeutic expertise and medical consultation in the
development and administration of CNS, oncology and pediatric clinical
trials. Leventhal has had a distinguished career as a biomedical research
executive spanning the academic, government and private sectors. These collaborations will utilize ParAllele's
application-specific SNP genotyping panel that is being commercialized as part
of an existing development partnership with Affymetrix, Inc.

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