For more information visit: http://www.
"The E2open MCD solution meets the requirements for companies to
comprehensively, yet cost-effectively address the eco-compliance challenge,"
said Richard Kubin, E2open vice president of PLM solutions and chair of the
National Electronics Manufacturing Initiative (NEMI) project on Materials
Composition Data Exchange.

Colorectal Cancer Rates among African Americans Continue to Rise

"In addition, it is compatible to our
overall architecture.

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Over 6,000 companies worldwide currently use
E2open for greater supply chain visibility and control through accurate,
timely and cost-effective access to information. Heinz
Derenbach , head of technology and development in central division
information processing at Bosch.

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"Not meeting these two directives
could cost companies millions. However when it is
detected early, the survival rate for colorectal cancer in African Americans
is 84 percent, according to the American Cancer Society . For this reason, Bosch made the decision to switch
from a divisional PDM structure to a global PLM structure, providing
the Group with a significant increase in synergy due to closer
collaboration and cooperation across all divisions--and faster
integration of strategically important suppliers into the product
development process. The risks and uncertainties that may affect
forward-looking statements include, among others: poor product sales,
long sales cycles, difficulty developing new products, difficulty in
relationships with vendors and partners, higher risk in international
operations , difficulty assimilating future acquisitions, difficulty
managing rapid growth, and increased competition .

maternal substances


Industry analysts have begun to alert companies to the MCD challenge. Like
Y2K preparations and Sarbanes-Oxley requirements, the broad business impact
and pending deadlines for eco-compliance present challenges to both business
and IT executives at each level of the supply chain.
E2open (http://www. In order for products to be developed on-time and on-budget,
these various disciplines must work together on an enterprise product
data view that is automatically updated with the latest
information--no matter where these designers and system engineers are
based in the world. Increasing the re-use
of information, parts and components will reduce costs and help the
company realize further improvements in product quality.matrixone.

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com) is the leading provider of software-as-a-service
to manage inter-company processes such as inventory management, order
management, demand/supply synchronization and multi-tier visibility,
integrating trading partners across multiple tiers of distributed global
supply and demand networks. To request a copy of the video please
contact Thomas Jefferson University Hospital at 1-800-JEFF-NOW. All other trademarks and service marks
are the property of their respective owners.

hazardous encompassing


We provide flexible solutions that unleash the creative power of
global value chains to inspire innovations and speed them to market.

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New Educational Video Fills the Gap for Needed Patient Outreach;
March is Colorectal Cancer Awareness Month

PHILADELPHIA, Despite advances in research and
treatment that continue to help many people live beyond a colorectal cancer
diagnosis, African Americans are more likely to die from the disease than any
other racial or ethnic group.
Parallel to that project, the MatrixOne PLM platform will be
introduced as a team data manager application allowing the integration
of component data from ECAD applications for improved electronic
design data management.

Forward-looking statements in this release are subject to risks
and uncertainties that could cause our actual results to differ
materially from those anticipated.

Various types of publications related to public health and safety.

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Specifically designed to manage the complexities surrounding new
environmental compliance initiatives, the E2open MCD Solution provides
integrated data collection capabilities along with reporting and business
intelligence tools to allow companies to efficiently manage the compliance of
their products, thereby limiting liabilities and maintaining uninterrupted
access to key product markets while reducing the cost of compliance across the
supply chain. E2open will host a Web seminar on January 27 to discuss this
important issue. In particular, companies must gather MCD data and
manage non-compliant elements across 100 percent of their supply chain. Knowing this, Edith P.
African-Americans are more likely to be diagnosed with colorectal cancer
in its more advanced stages when there are fewer treatment options available,
and they are less likely to live five or more years after being diagnosed than
other populations, according to the Cancer Research and Prevention Foundation. (NASDAQ: MONE), a leading provider of
collaborative product lifecycle management (PLM ) solutions for the
value chain(TM), today announced that the Bosch Group, one of Europe's
leading industrial and electronic corporations, has selected The
MatrixOne(R) PLM platform to be implemented across its global
operations to drive collaboration and speed product development. The WEEE
(Waste of Electrical and Electronic Equipment) directive will come
into effect in August 2005 and the RoHS (Restriction of the Use of
Certain Hazardous Substances in Electrical and Electronic Equipment)
will be in effect in July 2006.

About Bosch

The German Bosch Group is one of Europe's leading industrial
corporations, achieving a global turnover of EUR 36.
MatrixOne's customers include global leaders in the aerospace and
defense, automotive, consumer products, high technology, life
sciences, machinery, and the process industries, including Agilent
Technologies, General Electric , Honda, Johnson Controls, Philips,
Procter + Gamble, Siemens, and Toshiba.E.


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Later this year she
will lead a continuing medical education program designed to educate
physicians who treat African-Americans.

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D. But research suggests that regular
exercise, eating a diet rich in fruits and vegetables, moderate alcohol
consumption, and not smoking may help prevent cancer and other diseases in
general. In
particular, she has been very active in raising cancer awareness within the
African -American community and was the force behind another educational film
about breast cancer among African -American women.
The Special Population Network was created to build relationships between
large research institutions and community-based programs and to find ways of
addressing important questions about the burden of cancer in minority
communities.
Funding and production of "The Colon Cancer Puzzle: Putting all the Right
Pieces Together to Beat It" was made possible by an unrestricted educational
grant from Genentech BioOncology.


Bosch Selects MatrixOne PLM to Drive Collaboration and Speed Product Development


In addition, by optimizing its work processes and re-using
existing information, the Bosch Group will gain a competitive
advantage as they speed up product development and shorten
time-to-market--all while reducing costs.

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The
solution manages data collection from all suppliers, encompassing all related
part numbers. A privately-held company,
E2open's largest customers include Hitachi (HIT), IBM (IBM), LG Electronics,
Matsushita Electric Industrial (MC) (Panasonic), Seagate Technology (STX),
Solectron (SLR), and Wistron., an
oncologist at Thomas Jefferson University, became the force behind an
educational film, The Colon Cancer Puzzle: Putting all the Right Pieces
Together to Beat It, now available to physicians and healthcare professionals
to educate their African-American patients and the community at-large about
colorectal cancer and the importance of early detection.
The most effective risk reduction tool for colorectal cancer is undergoing
routine colorectal screening tests.

Business Editors/Technology Editors

WESTFORD , Mass. Moreover, Bosch has an
additional goal for their implementation of the MatrixOne PLM
platform --to integrate the three worlds of mechanics, electronics and
software.
"After careful consideration , we decided on MatrixOne because of
its high level of flexibility and adaptability," said Dr.

MatrixOne and the MatrixOne logo are registered trademarks and "a
leading provider of collaborative product lifecycle management (PLM)
solutions for the value chain" and Materials Compliance Central are
trademarks of MatrixOne, Inc.

hazardous reflects

E2open is the industry's
only solution to combine inter-company process management functionality, event
management tools, performance management capabilities and an open B2B
integration platform delivered in an on demand model, resulting in lower total
cost of ownership and shorter deployment cycles.

atsdr encompassing

Further, it provides tools to meet the required documentation should
a company need to establish proof of compliance and it is flexible to rapidly
and affordably accommodate changes to eco-compliance standards.
These new EU regulations effect Europe's automotive and electronic
industries in particular, as they are aimed at reducing the use of
hazardous materials and promoting the recycling of materials.

About MatrixOne

MatrixOne, Inc. filings.

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Like all E2open solutions, the E2open MCD Solution is delivered in a
software-as-a-service model to lower costs and complexity, including all of
the hardware, software, hosting services and ongoing management capabilities.
Despite advances in treatments, incidence rates for African Americans are
increasing: In recent years, colorectal cancer incidence has increased 46
percent among African -American men and 10 percent among African-American
women. MatrixOne
(http://www.

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New E2open Solution Enables Cost Effective Eco-Compliance for WEEE and RoHS Across Global Supply Chains

com/MCD/MCDMain .htm.----

Global Rollout of the MatrixOne PLM Platform to Integrate all
Existing Company Systems while Improving Information Re-use
Across the Company

MatrixOne, Inc.

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In highly competitive global markets, innovations based on new
approaches in product development and production are pivotal for a
company's success.
With 232,000 employees and more than 50 per cent outside Germany, the
Group is active in three divisions: Automotive Technology , Industrial
Technology and Consumer Goods and Building Technology.

toxic encompassing


Rapidly approaching legislation such as the European Union's (EU) Waste
Electrical and Electronic Equipment (WEEE -- deadline, August 2005) and
Restriction of Hazardous Substances (RoHS -- deadline, July 2006) require OEM
producers to understand the composition of their products and maintain access
to technical records on the levels of controlled or hazardous materials that
may be present prior to shipment of a finished good into any EU country. Today,
few companies are able to adequately track material composition to address MCD
requirements and are at risk of being fined and having their products
impounded resulting in decreased sales, lost market share and potentially
negative press coverage.
"Any company doing business in the European Union (EU) has less than seven
months to begin complying with the Waste Electrical and Electronic Equipment
(WEEE) directive and less than eighteen months to come into compliance with
the Restriction of Hazardous Substances (RoHS) directive," said Eric Karofsky
in the AMR Research Alert, January 14, 2005."
Throughout her career, Mitchell has been committed to educating African
Americans about colorectal cancer with projects such as The Colon Cancer
Puzzle: Putting all the Right Pieces Together to Beat It.
There may also be genetic factors that contribute to the higher incidence
rate of the disease among the African-American population."

Project Stages

As a first phase, the MatrixOne PLM platform will be installed in
two divisions and used as an information system on a global level.
Bosch also plans to create an e-sourcing platform for project
purchasing, based on the MatrixOne PLM Platform.com/) is headquartered in Westford,
Massachusetts with locations throughout North America, Europe, and
Asia/Pacific.

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It helps to manage and track material composition data,
requests and change notices and includes MCD data collection forms based on
the emerging RosettaNet Automated Enablement (RAE) program, along with
capabilities for tracking business exceptions such as part non-conformance and
supplier non-response. "The solution enables companies to efficiently
collect consistent and high quality MCD data from all of their trading
partners , regardless of their integration or communication capabilities
-- this has proven to be the most difficult and costly issue in addressing the
problem.e2open.
Mitchell has authored and co -authored more than 100 articles, book
chapters, and abstracts on cancer treatment, prevention and cancer control. To comply with these laws,
manufacturers must implement specific processes in order to collect,
organize, analyze and report data on all materials and substances used
in new products .

newsfeeds cohort

They must be taken seriously and be an
executive-level priority. The E2open MCD
Solution is architected for rapid deployment and can easily integrate with a
company's existing internal systems of record , such as an ERP system. "If members of
the community are educated, they can recognize when they are at risk and ask
the right questions regarding prevention, screening and treatment. Over
time, thousands of Bosch employees worldwide will be linked to the
MatrixOne PLM platform and Bosch's existing product data management
(PDM) systems will be integrated into the MatrixOne system. For
this purpose , data from existing PDM installations in different Bosch
divisions will be made available in MatrixOne PLM. (NASDAQ: MONE) is a recognized leader in
delivering collaborative Product Lifecycle Management (PLM) solutions.

cohort apha

"

About E2open Inc.
"It is essential that physicians talk to their patients, particularly
their African-American patients, about colorectal cancer," said Mitchell,
clinical professor of medicine, division of Medical Oncology, Jefferson
Medical College of Thomas Jefferson University in Philadelphia.
Mitchell also is the principal investigator of the Special Populations
Network for Cancer Control at the Thomas Jefferson University in Philadelphia.

communicable atsdr

Such statements may relate, among
other things, to our plans, objectives and expected financial and
operating results.

hazardous immunization

, E2open announced today the
E2open Material Composition Declaration (MCD) Solution for collecting,
maintaining and reporting data about the contents of electronics products for
compliance with emerging environmental and hazardous materials rules and
regulations.

epidemiologic tabloid

Material Composition Declaration Solution Provides Automated Data Collection
and Management to Address Pending European Union Regulations

REDWOOD CITY, Calif."
To meet the needs of companies facing these new eco-regulations, the
E2open MCD Solution includes data collection and integration, application
software , data warehousing, trading partner on-boarding, report generation,
performance management, decision support and issue resolution tools for
managing MCD compliance both internally and with partners . Mitchell, M.
In addition, MatrixOne's new Materials Compliance Central(TM)
application will be implemented, thus ensuring that the new laws
regarding obligatory reports on materials and pollutants are observed. The company was
founded in 1886 by Robert Bosch, when he opened his "Workshop for
Precision Mechanics and Electrical Engineering" in Stuttgart.

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With
the new regulations, ignorance regarding the composition of any component or
material in the product, regardless of where in the supply chain it originated
-- either with EMS providers, component suppliers or distributors -- will not
excuse companies or be a defense to non-compliance.
Research indicates several reasons for this: Environmental factors, access to
diagnostic testing and healthcare, cultural factors that may delay diagnosis
or affect treatment choices, biological features of the disease, and lack of
physician communication . For more about the
risks and uncertainties of our business, see our periodic and other
S.C.

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e2open .4 billion in 2003.

maternal tuberculosis

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