Microbia's Precision Engineering(TM) business
unit generates cash to fund the therapeutics effort by improving
biomanufacturing efficiencies for leading pharmaceutical and chemical
manufacturers. Formal continuing education credits are available for psychologists,
social workers , marriage and family therapists, and mental health counselors.

SAMHSA, is a public health agency within the Department of Health and
Human Services.

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Microbia expects to
initiate Phase II studies in IBS-C patients later this year.

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, Vice President of Research and
Development at Microbia . Microbia has raised $99 million in private equity financing and
is located in Cambridge, Massachusetts .

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, Microbia, Inc. Preclinical studies
demonstrated that MD-1100 promotes gastrointestinal transit and secretion and
reduces gastrointestinal hypersensitivity -- activities believed to be
important for treating the pain and constipation associated with IBS-C.

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Left untreated, distress can have a serious impact on patients' overall
quality of life and even contribute to raising healthcare costs. Project Recovery
expects to provide group and individual therapy, anger management, supportive
housing , and training.

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MD-1100, an orally delivered compound, is a potent agonist of guanylate
cyclase -C, a receptor on the surface of intestinal cells. WASHINGTON, The Substance Abuse and Mental Health
Services Administration (SAMHSA) today announced an $11 million award to the
State of Florida to meet the needs of those suffering long-term trauma as the
result of the hurricanes of 2004.

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In the second
half of 2005, Microbia expects to initiate a Phase II study for MD-1100 for
the treatment of IBS-C and a Phase I study for MD-0727, the company's lead
therapeutic for dyslipidemia. The funds will be used to serve the
27 most highly impacted Florida counties through Project Recovery, a state
initiative, completely funded by the federal government, that will establish
multidisciplinary treatment teams in the affected areas.

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"SAMHSA has been helping Florida since the first hurricane struck the
state," SAMHSA Administrator Charles Curie said.

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During the first year of this program, 500 NASW members will receive these
hours free of charge.
The Florida Department of Children and Families submitted its application
for this current grant on March 22 , 2005.

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-- Phase IB Multi-Dose Study Initiated --

CAMBRIDGE, Mass." Matthew Loscalzo MSW of
the Moores Cancer Center at UCSD lent his expertise as a consulting author on
three of the lectures.

For further information on this and other APOS programs, please contact
APOS Headquarters, 2365 Hunters Way, Charlottesville, VA 22911, 434.5 million in immediate emergency aid
funds through the FEMA Crisis Counseling and Training Assistance Program.

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"We're encouraged that MD-1100 has performed as expected based on our
preclinical data," said Mark Currie, Ph.
617-621-8304
sbrady@microbia.
Each presentation has also been accredited by the University of South
Florida.

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APOS is also pleased to announce an exciting, new partnership with the
National Association of Social Workers (NASW) to offer continuing education
social work contact hours to NASW members for the first three presentations. The teams will work
with displaced people, individuals with continued stress, and special
populations such as immigrants, migrant workers and older persons .

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Health care costs associated with IBS exceed $25 billion annually., According to an extensive
Johns Hopkins study, almost half of all cancer patients suffer from symptoms
of distress during their illness significant enough to warrant psychological
care.
This program is jointly sponsored by the University of South Florida and
APOS, with support from the Individual Cancer Assistance Network (ICAN), a
philanthropic program of the Bristol Myers-Squibb Company designed to build
community -based cancer counseling capacity to serve patients and their
families.

Support Groups for Social Anxiety Disorder (Social Phobia) (the fear of being humiliated or embarrassed in front of other people).

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Of the
three IBS subgroups -- constipation-predominant (IBS-C), diarrhea-predominant
(IBS-D), and alternating (IBS-A) -- 30% to 40% of patients suffer from IBS-C.

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Contact:
Susan Brady
Corporate Communications
Microbia, Inc.

SAMHSA Awards $11 Million Mental Health Grants to Florida for Continued Services for those Affected by Hurricanes

This award builds on current SAMHSA
initiatives that have provided over $5.

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today announced
that it has completed a Phase IA study for MD-1100, a compound under
development for the treatment of constipation-predominant irritable bowel
syndrome (IBS-C) and other gastrointestinal disorders. The objectives of Phase IB are to assess the
safety, pharmacokinetics and pharmacodynamics of MD-1100.

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The Microbia drug
discovery team designed MD-1100 to specifically target the site of action on
the intestinal epithelium, avoiding general systemic exposure and thereby
resulting in potential safety advantages for patients.

About Irritable Bowel Syndrome
One out of six adults in developed countries suffers from irritable bowel
syndrome (IBS), a chronic condition marked by abdominal pain and disturbed
bowel function.
Therapies traditionally used to treat the symptoms of IBS have been generally
ineffectual or poorly tolerated. CHARLOTTESVILLE, Va." Michael Weitzner MD, Helios Pain +
Psychiatry Center , follows with "Palliative and Supportive Care" and Jennifer
Strickland PharmD addresses "Cancer Pain Management. NASW is proud to offer this program to its members to
increase awareness of the complexities surrounding the care for patients with
cancer. The current program will address the more serious
problems that emerge over time. The agency is responsible for improving the accountability,
capacity and effectiveness of the nation's substance abuse prevention,
addictions, treatment and mental health service delivery system.

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In addition, treatment with MD-1100 showed
pharmacodynamic effects that had been anticipated by preclinical studies
investigating the compound's activity.

About Microbia
Microbia (http://www.com) is an entrepreneurial pharmaceutical
company dedicated to the science and art of great drugmaking.

APOS Launches Cancer 101 A New Online Curriculum

5350 ,
info@apos-society.

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microbia. "The earlier aid was
designed to assist the general population in recovering from the psychological
effects of a disaster."
The program will provide direct mental health services and link
individuals and families with other community services. Substance abuse and mental health screening and
treatment services will be provided.

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Cherie Andrews RN and Paul Jacobsen PhD of the Moffitt Cancer Center
present "Cancer Overview: Parts I and II. It can take several months for symptoms of
post-traumatic stress disorder, clinical depression and substance abuse to
appear, and for people to recognize they need additional help.

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Microbia Successfully Completes Phase IA Trial of MD-1100 for IBS-C and Other GI Disorders

MD-
1100 may have additional therapeutic benefit in other disorders such as
gastroesophageal reflux disease (GERD), chronic constipation , and dyspepsia.org.

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IBS accounts for 12% of adult visits to primary care
physicians and is the most common disorder diagnosed by gastroenterologists. To help meet
this problem, the American Psychosocial Oncology Society (APOS) has developed
a free online education program, Cancer 101 for Mental Health Professionals,
to give these professionals insight into the cancer experience: its treatment,
common symptoms and side effects.

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In this study of 30
healthy volunteers, MD-1100 was shown to be safe and well tolerated, with no
detectable systemic absorption.
The ongoing Phase IB trial for MD -1100 consists of a seven-day, multi-dose
study with 60 healthy volunteers.293.