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Medtronic , Inc.medtronic.

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About Medtronic, Inc.

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org.

Medtronic Receives Humanitarian Use Device Designation for Treatment of Obsessive Compulsive Disorder

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With the increase of environmental disasters in the world such as
hurricanes, earthquakes, the Iraq war, and September 11, psychiatric
researchers have noted an increase in Post-traumatic Stress Disorder (PTSD)
after individuals experienced any severely distressing or traumatic event. Its web site is www.

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NEW YORK , What do Barbara Streisand, Donny
Osmond, Carly Simon, and 17 million Americans have in common? They have all
suffered from an anxiety disorder, one of America's most common mental
illnesses . Those who have suffered for more than
five years with chronic, treatment-resistant OCD, and who are
candidates for anterior capsulotomy, fall within the HUD designation
for DBS."

About Activa(R) Therapy

Approximately 30,000 implants of Medtronic's Activa Therapy have
been conducted worldwide for the three most common movement disorders:
Parkinson's disease, essential tremor, and dystonia (also available
under an HDE).

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To help individuals learn about anxiety disorders, their
symptoms, and effective treatments, mental health professionals are available
for this screening as part of a free national outreach program. "That's the sad news; the good news is these
illnesses can quickly and effectively be treated. for the Intercept(TM) Epilepsy Control System, the company's
brain stimulation therapy that may reduce seizure rates in patients
with epilepsy.

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"Anxiety disorders bring tremendous suffering and pain to millions of
Americans each year," says Mary Guardino , founder of the National Anxiety
Disorders Screening Project."

For additional information , or to find a screening site in your area,
please call toll free, 1-888-442-2022, or visit our Web site at
http://www.
Medtronic is currently conducting a pivotal clinical trial in the
U.html

About Humanitarian Use Devices (HUDs) and Humanitarian Device
Exemptions (HDEs)

The FDA defines HUDs as devices used in the treatment of rare
medical conditions (less than 4000 per year in the US).com

Any statements made about the company's anticipated regulatory
approvals are forward-looking statements subject to risks and
uncertainties such as those described in Medtronic 's Annual Report on
Form 10-K for the year ended April 30, 2004.

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"Our work in OCD, and research in depression demonstrate our
commitment to the psychiatric field, and to patients with very few
treatment options.S.
More information regarding Medtronic's Activa Therapy, including
approved indications and safety information is available at
http://www.

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Individuals who suffer from an anxiety disorder experience a
variety of symptoms that can include spontaneous panic attacks, endlessly
checking and rechecking their actions, persistent and uncontrollable worry,
and anxiety in social situations .

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Business Editors/Health Editors

MINNEAPOLIS----

Leader in Brain Stimulation Therapy Seeks to Help Patients Suffering
from Debilitating Psychiatric Conditions

Medtronic, Inc.

com/activa/physician/activa.

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prnewswire.

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Mary Guardino
http://profnet.3 million adult Americans.

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Press Contact: Jeanine Christiana May 2005
Facility Name: Freedom From Fear
Phone: 718-351-1717

Available Topic Expert(s): For information on the listed expert (s), click
appropriate link."
According to the National Institute of Mental Health, OCD affects
about 3., headquartered in Minneapolis, is the world's
leading medical technology company, providing lifelong solutions for
people with chronic disease.

struggles disorder

"Improving access to our leading DBS therapy is another way in
which Medtronic hopes to better patients' overall health," said
Tremmel.

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The program
includes viewing a video, completing a screening questionnaire, meeting a
doctor or mental health professional to review the questionnaire, and
receiving information about various anxiety disorders and mental illnesses.com/ud_public.
This special FDA designation may make the use of Medtronic 's
leading DBS therapy possible among patients with this disorder under a
Humanitarian Device Exemption (HDE).
"Obsessive compulsive disorder is not rare, but some people with
severe OCD never find adequate relief from its debilitating and
disruptive symptoms with existing treatment options," said Jon
Tremmel, president, Medtronic Neurological. "These patients deserve a
better quality of life , which is one of the main reasons why we are
pursuing this much needed therapy.

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Free Help Available for Anxiety Sufferers on National Anxiety Disorders Screening Day May 4 2005

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Anxiety disorders include: Panic Disorder,
Generalized Anxiety Disorder (GAD), Social Phobia, and Obsessive Compulsive
Disorder (OCD). Participating in the
screening day on May 4, 2005, is the first step in finding help. The company expects to file an
HDE application for the condition later this year. After an HUD
designation is made, the company has the opportunity to submit data
supporting safety and probable benefit for the affected population. If
the FDA then determines the device meets these criteria , it will grant
an HDE, allowing for qualified distribution and use of the device for
the specific indication.

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Untreated anxiety disorders often can lead to substance abuse, depression,
and even suicide.

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Standard treatments such as
pharmacotherapy and Cognitive Behavioral Therapy (CBT) fail to work
for a subset of these patients. Actual results may differ
materially from anticipated results.

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medtronic.

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(NYSE:MDT) today announced that the United States
Food and Drug Administration (FDA) has designated Activa(R) Deep Brain
Stimulation (DBS) Therapy as a Humanitarian Use Device (HUD) for the
treatment of chronic, treatment-resistant obsessive compulsive
disorder (OCD) as an alternative to anterior capsulotomy, a form of
destructive, irreversible neurosurgery.

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