tissuescience. and
international businesses, including tax obligations and risks, product
liability and intellectual property litigation losses, reimbursement levels
from third-party payors, general industry and market conditions and growth
rates and general domestic and international economic conditions including
interest rate and currency exchange rate fluctuations.
As well as post-menopausal women, SBI estimates that 90 percent of women
in the 75-79 age bracket have symptomatic OA in the hands -- among the 21
million Americans who suffer from the disease in one form or another. The Center offers comprehensive
care for patients with a broad range of musculoskeletal and related
disorders.

injuries wound

It is a durable
implant, highly resistant to breakdown by enzymes in the body.S.
"In one short year, SBI has quickly become identified as the single source
provider of products and services to treat bones and joints from the finger
tips to the shoulder, and from the toes to below the knee.
(Click here for details) advantages of this approach over conventional techniques. Martin,
MD, will narrate the webcast, which will include an overview of pre- and
post-surgical considerations, patient candidacy , and risks and benefits of
arthroscopic rotator cuff repair.or-live.

repetitive pribut

(NYSE: ZMH; SWX: ZMH) today announced that it has launched an innovative
biological patch for the repair of rotator cuff injuries in the shoulder. The ZCR Patch also
offers reduced inflammatory response characteristics within the body due to
TSL's proprietary processing technology."
Zimmer has begun marketing the ZCR Patch within the United States, and
expects to make the product available on a global basis later this year.zimmer., the outcome of the Department of
Justice investigation announced in March 2005 and the pending informal SEC
investigation of Centerpulse accounting, price and product competition , rapid
technological development, demographic changes, dependence on new product
development, the mix of our products and services, supply and prices of raw
materials and products, customer demand for our products and services, control
of costs and expenses, our ability to form and implement alliances ,
international growth, governmental laws and regulations affecting our U.
In addition to its U.lendau@artimplant. Martin added, "Broadcasting this surgery live presents a tremendous
opportunity to introduce this technique to patients and to allow an open
exchange of ideas and opinions from other surgeons. VNR:
http://www.

wounds repetitive

Readers of this document are cautioned not to place undue reliance
on these forward-looking statements, since, while we believe the assumptions
on which the forward -looking statements are based are reasonable, there can be
no assurance that these forward-looking statements will prove to be accurate. and Europe of its biodegradable
Artelon(R) Spacer CMC-I exceeded 500 units used in treating osteoarthritis
(OA) at the base of the thumb. "It is also a relatively simple procedure to teach and perform --
requiring no special instrumentation or unfamiliar techniques ," he added.

About SBI
Small Bone Innovations, Inc.totalsmallbone.
This approach enables surgeons to preserve attachment of the deltoid -- a
large muscle in the shoulder -- and results in faster recovery time with
less inflammation, discomfort, and scarring.

fatalities chondromalacia

Zimmer believes the ZCR Patch offers several potential advantages compared
to current products or treatments. The Company is supported
by the efforts of more than 6,500 employees worldwide.

Visit Zimmer on the worldwide web at http://www.
In its first full year of operation, since its formal introduction at the
2005 American Academy of Orthopaedic Surgeons (AAOS) annual convention, SBI
has been marketing 42 products used to treat arthritis or trauma in small bone
and joint devices. Also, earlier this month, Artimplant received
a European CE mark that will facilitate SBI's marketing of the Artelon (R) DRU
Spacer intended for treatment of OA in the distal radio-ulnar (DRU) joint of
the wrist .S.2 million, in January, 2006 Based on data provided by
Venture Source, this was the largest venture capital investment ever recorded
in the field of orthopedic devices." Patient questions will
also be answered.

injuries rotator

com

Zimmer Safe Harbor Statement
This press release contains forward-looking statements within the safe
harbor provisions of the Private Securities Litigation Reform Act of 1995
based on current expectations, estimates, forecasts and projections about the
orthopaedics industry , management's beliefs and assumptions made by
management. Securities and Exchange Commission. (SBI )
reported that annual sales in the U. Of these, the company said the CMC-I Spacer is a big
seller .
Small Bone Innovations, Inc. Arthroscopic rotator cuff
repair uses a small camera to view and guide repair of the rotator cuff.

consolidates tetanus

WARSAW, Ind."
Zimmer already participates in the shoulder repair market with products
such as Bigliani/Flatow(R) The Complete Shoulder Solution, one of the world's
leading total shoulder replacement systems, and the Anatomical Shoulder(TM)
System."
SBI said it plans to initiate a new series of clinical trials in the U. was founded in 2004 by Viscogliosi Bros. (hand/wrist/elbow arthroplasty and trauma products -- USA); Envision,
Inc. Artelon(R) is a degradable
polyurethane-urea patented biomaterial that acts as a temporary support for
healing tissue. ET, orthopedic surgeons
at Brigham and Women's Hospital (BWH) in Boston will broadcast a live
arthroscopic rotator cuff repair. Higgins, MD, Chief of Sports Medicine and Chief of the Shoulder
Service within the Department of Orthopedic Surgery at Brigham and Women's
Hospital, will perform the procedure.

ukas sportsmed

"
Among those surgeons currently implanting the Spacer, Alejandro Badia, MD,
a leading hand surgeon based in Miami, FL, said: "The use of tissue-sparing
technology holds immense promise. (implant manufacturing -- USA); Actipore(TM) (porous metal technology --
Canada); Artelon (R)(biologically active + biodegradable technology --
Sweden); Xtremi-T, LLC (resorbable trauma technology -- USA); and Fixano,
S. For additional information, please contact: Tord Lendau, CEO,
phone +46 (0)31 746 56 00, +46 (0)708 369 403, email:
tord.
On March 9 at 4:30 p. There's also less pain after the surgery, more rapid
restoration of motion, and easier rehabilitation.

wound ukas

"With nearly 250,000 rotator cuff repairs annually in the United States
alone, this is a substantial market segment that is growing in both primary
and revision procedures," said Zimmer Chairman, President and CEO Ray Elliott. For example, the ZCR Patch's high
resistance to collagenase activity and breakdown in the body promotes
increased repair stability throughout the healing process.
This cautionary statement is applicable to all forward-looking statements
contained in this document.
Laurence D.ram This event is being
simulcast live by the National Library of Medicine's MedlinePlus.

clostridial fractures

, Zimmer Holdings, Inc.
Marketed by TSL as Permacol(R), it also has been available in the United
Kingdom for rotator cuff repairs and was previously cleared in the United
States for urological treatments , hernia repairs and plastic and
reconstructive surgery of the head and face (sold under various brand names).
Nicholson said. "It has only taken 12 to 15 minutes to trim and suture in the
graft after rotator cuff repair, so it does not add any significant OR time. The Company floated in November 2001 and is listed on the
Alternative Investment Market (LSE: TSL). The Spacer has been
our only biologics offering but it has taken off like a rocket," Anthony G.

cuff injuries

For more information, please visit
the web site at http://www. These statements are not guarantees of future
performance and involve risks , uncertainties and assumptions that could cause
actual outcomes and results to differ materially .

Biodegrable CMC Spacers for Basal Thumb OA Drive Growth at Small Bone Innovations Inc.

Surgeons in U.

Bites, stinges, athletic injuries, back, dislocation, burns, contusions, frostbite, heat stroke , motion sickness, shock, spinal cord injuries, sprains, wound infections and related conditions.

fractures sportsmed

Greg
Nicholson at the Rush University Medical Center at Rush-Presbyterian-St.

S.com .

PRESS RELEASE REMINDER: OR-Live.com Presents: BWH Orthopedic Surgeons Demonstrate New Minimally Invasive Approach to Rotator Cuff Repair -- An Innovative Proce

Scott D.or-live.

consolidates stings

Zimmer Launches Biological Rotator Cuff Repair Product

The condition particularly affects as many as
one-in-four post-menopausal mothers, according to the company.
The Spacer technology was developed by Artimplant AB of Sweden
(STO: ARTI-B) and sold worldwide by SBI under an exclusive marketing license. Procedures capable of restoring function are
a compelling alternative to drug therapy or more aggressive surgical
procedures .
VB's acquisitions and technology licenses include: Avanta Orthopaedics,
Inc. (SBI) completed a Series B financing, raising
a record total of $42.

sprains sobering

"With the ZCR Patch, we will be able to address the unique needs of
orthopaedic surgeons who require a material to reinforce their rotator cuff
surgical repairs but with several important new advantages.
Viscogliosi, SBI's Chairman and CEO noted. Pain relief and
functional results of arthroscopic rotator cuff repair are equivalent to
open repair with an important difference -- there's no risk of the serious
complication of deltoid muscle detachment .

cuff wounds

In November
2002, the Food and Drug Administration cleared the technology for use in the
United States for treatment of rotator cuff injuries of the shoulder.S.
For more information visit: http://www.se or visit: http://www.com/BrighamandWomens/1374 to learn more.

sickness rotator

The two companies signed a multi-year, exclusive
distribution agreement in 2003.

About Tissue Science Laboratories
Founded in 1995, with headquarters in Aldershot, Hampshire, TSL is a
medical technology company specialising in tissue repair and replacement with
a proprietary sheet product, derived from porcine dermis, called Permacol(R). (broad line of small bone + joint implants -- France). Patients also generally
experience better range-of-motion and accelerated rehabilitation.

sportsmed cuff

S. SBI also noted that 25 percent of athletic injuries occur in the
hand and wrist.A.

About Artimplant AB
Artimplant is a public company based in Vastra Frolunda, Sweden and is
listed on the Stockholm Exchange, O-list .m.

A tear of the rotator cuff is a common injury that often leads to pain and
sometimes weakness in the shoulder and upper arm.gov

sunburn puncture

The
underlying technology was developed by Tissue Science Laboratories plc (TSL)
of the United Kingdom and is being marketed by Zimmer as the Zimmer(R)
Collagen Repair (ZCR) Patch.
Luke's Hospital in Chicago. Zimmer
disclaims any intention or obligation to update or revise any forward-looking
statements, whether as a result of new information, future events or
otherwise.
to explore the full potential of the Artelon(R) technology within the bounds
of its existing licensing agreement with Artimplant AB.

dislocation rotator

In addition, the ZCR Patch offers
ease of use because the product is flexible and strong, can be stored at room
temperature instead of requiring refrigeration and can be used without the
need for rehydration by the surgeon. For a further list and
description of such risks and uncertainties, see the disclosure materials
filed by Zimmer with the U.S.,
LLC, (VB), the New York-based merchant banking firm that specializes in the
musculoskeletal /orthopedic sector.

repetitive fatalities

About Zimmer
Founded in 1927 and headquartered in Warsaw, Indiana, Zimmer is the
worldwide #1 pure-play orthopaedic leader in designing, developing ,
manufacturing and marketing reconstructive and spinal implants, trauma and
related orthopaedic surgical products.

fatalities sickness

In all, the implant technology has been used in more than 100,000 procedures
worldwide .
The first ZCR Patch procedure was performed in April 2005, by Dr.
Zimmer's 2004 sales were approximately $3 billion. These risks and
uncertainties include, but are not limited to, our ability to successfully
integrate Centerpulse AG and Implex Corp.
According to the company, only heart disease causes more chronic disability
than does OA.artimplant.com/rams/brw-1374-mkw-q.

chondromalacia wounds

The ZCR Patch is a chemically crosslinked, acellular sheet of
collagen/elastin that is derived from porcine dermis. Forward-looking statements may be identified by the use of
forward-looking terms such as "may," "will," "expects," "believes,"
"anticipates," "plans," "estimates," "projects," "targets, " "forecasts," and
"seeks" or the negative of such terms or other variations on such terms or
comparable terminology. and European markets, Artimplant has recently
received government approvals that will enable SBI to market the Artelon(R)
Spacer in Canada and Australia. VB created SBI as the first company to
focus purely on small bone + joint science. By integrating established
companies and professionals in the field, SBI today offers a broad, clinically
proven portfolio of products and technology to treat trauma and diseases in
small bones + joints. The webcast is intended to educate
physicians and patients about the latest surgical approach for rotator cuff
repair and provide an overview of the many advantages of this approach over
conventional techniques.

clostridial wound

"I believe the implantation technique is reproducible and effective," Dr. and Europe treating more basal thumb OA cases using
Artelon(R) technology

CHICAGO, Small Bone Innovations, Inc.
Michael Simpson, SBI's President and COO, said: "To complement the
Artelon(R) Spacer, we are adding several other Artelon(R) designs for
repairing or replacing the CMC joint -- all under our original license -- to
complete a portfolio of biodegradable implants for the thumb. Orthopedic surgeon Scott D. Martin, MD, said, "Arthroscopic rotator cuff repair is minimally
invasive and decreases operation time compared to other rotator cuff
procedures.

Visit http://www.

tetanus chondromalacia

TSL has launched successfully different formulations of the product and built
a development pipeline that addresses the large and fast growing surgical
implant market.
SBI has similar licenses to develop and sell Artelon(R) fiber-based products
for use in the hand, wrist, fingers and feet.com ."

Dr.

stings strains

Zimmer has operations in more than 24
countries around the world and sells products in more than 100 countries.com .S.

"The success of the Artelon(R) Spacer, according to many of the 100-plus
surgeons using the technology, is its ability to relieve pain and restore
function through improving pinch strength without needing to harvest tissue
from the patient's body -- unlike other basal thumb procedures ," Viscogliosi
said.

Arthroscopic rotator cuff repair is one of many new options available at
the BWH Orthopedic and Arthritis Center.