LineaGen Announces Promotion of Michael Paul Ph.D. to President and COO

Prior to joining LineaGen,
Michael worked for the start-up company Huntsman Biotechnology Corporation as
V.D. Dr.

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The disease is spread by many species of
mosquitoes, which carry the virus from reservoirs to humans. In addition, the company collaborates with major pharmaceutical
companies and biotechnology companies that give it access to complementary
technologies or greater resources. LineaGen provides
industry partners with breakthrough genetic research programs that leverage an
extensive biosample repository coupled with detailed clinical data and decades
of medical and genetic information from both population-based studies and
studies on multigenerational families. LineaGen's key asset is its ability to
provide commercial access to research using the Utah Population Database and
Utah Genetic Reference Project .

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Subjects will
be monitored for safety and immune responses against the encoded WNV proteins.LineaGen .

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The
development time and safety advantages of our technology may be critically
important for emerging diseases, which often spread rapidly and are
potentially life-threatening. Potential applications of the company's DNA
delivery technology include DNA vaccines for infectious diseases or cancer, in
which the expressed protein is an immunogen; cancer immunotherapeutics, in
which the expressed protein is an immune system stimulant; and cardiovascular
therapies, in which the expressed protein is an angiogenic growth factor. Prescott, M."
Michael S.

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D. Paul serves on the board of
the Utah Life Science Association and AnzenBio. Paul
received his B. degree in
Biochemistry and Molecular Biology from the University of Utah.

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To develop a human vaccine using
this approach , however, could require many years of further development and
testing to provide sufficient proof of safety and effectiveness. Forward-looking statements include statements about the
advantages of using Vical's DNA delivery technology in the development of
vaccines against WNV or other infectious diseases, the makeup, development,
uses and beneficial effects of such vaccines, and the option to exclusive
commercialization rights to the WNV vaccine, as well as the company's focus,
collaborative partners, product candidates, and developmental status. This history of success has been expanded to disease areas
including autoimmune and inflammatory disorders, respiratory disease,
metabolic disorders, central nervous system disorders, and age-related
conditions.

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Leveraging the inherent advantages of our DNA delivery technology, we have
rapidly constructed vaccines and advanced them to human testing. Risks
and uncertainties include whether vaccines for WNV or other infectious
diseases will be developed and approved, whether use of Vical's technology in
such vaccines will provide protective immune responses to such diseases and
will result in products that are safer, simpler and faster to manufacture than
traditional vaccines, whether any product candidates will be shown to be safe
and efficacious in clinical trials, the timing of clinical trials, whether
Vical or its collaborative partners will seek or gain approval to market any
product candidates, the dependence of the company on its collaborative
partners, and additional risks set forth in the company's filings with the
Securities and Exchange Commission., Business Development and for the publicly traded biopharmaceutical
company NPS Pharmaceuticals, Inc.
Headquartered in Salt Lake City, Utah, LineaGen draws on a proven process
for genetic discovery at the University of Utah that has led to the discovery
of multiple disease -causing genes in cancer, heart disease, and neurological
disorders.

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A similar vaccine construct was shown in independent tests at the U. But
approximately one out of every 150 infected people develops serious disease
symptoms of the central nervous system, such as headache, high fever, tremors ,
convulsions, numbness, vision loss, coma, and paralysis lasting several days
to several weeks , potentially with some permanent neurological damage. The company
disclaims, however, any intent or obligation to update these forward-looking
statements. SALT LAKE CITY, Utah, LineaGen Research Corporation
today announced that Michael S. Paul will continue to hold the position of Chief Operating
Officer. Paul also interned at the University of Utah Technology Transfer
Office where he participated in the marketing of University inventions to the
pharmaceutical and biotechnology industry.

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SAN DIEGO, Vical Incorporated
(Nasdaq: VICL) announced today that initial human testing of an
investigational vaccine targeting West Nile virus (WNV) has begun at the
National Institutes of Health's (NIH) Clinical Center in Bethesda, MD. Vical manufactured
research and clinical supplies of the vaccine, and has an option to exclusive
commercialization rights. Most infected
people have no disease symptoms , and some have only mild symptoms. On the Net: http://www.

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These strategic partnerships provide the
company with mutually beneficial opportunities to expand its product pipeline
and serve significant unmet medical needs.

This press release contains forward-looking statements subject to risks
and uncertainties that could cause actual results to differ materially from
those projected.

Contacts: Investors: Media:
Alan R.

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Centers
for Disease Control and Prevention to protect horses from WNV after a single
injection.

About Vical
Vical researches and develops biopharmaceutical products based on its
patented DNA delivery technologies for the prevention and treatment of serious
or life-threatening diseases.vical. Prescott said, "Michael embodies an exceptional combination of
personal and professional excellence in both science and business, and I am
extremely pleased to announce his promotion to President.

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com.
Dr. In
these roles, he led multidisciplinary product development teams, formulated
strategic development alternatives for management, and was responsible for the
strategic management of corporate intellectual property.

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The trial will enroll 15 healthy adult volunteers, who will each
receive three injections at approximately four-week intervals. Engbring Susan Neath
Vical Incorporated Atkins + Associates
(858) 646-1127 (858) 527-3486
Website: http://www. Paul, Ph. Stephen M.D.

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, who previously held the titles of
President and Chief Executive Officer, will continue to serve as LineaGen's
CEO .org

For LineaGen:
Michael Paul
President and COO
(801) 585-0619

Media Contact:
Kari Lampka
MacDougall Biomedical Communications
508-647 -0209
klampka@macbiocom.

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S. The
company has retained all rights to its internally developed product
candidates. He has contributed
significantly to LineaGen's development and success since inception and has
recently played an instrumental role in securing agreements with some of the
most influential and respected businesses in our industry, including IBM and
Amgen. Paul, Ph.

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The
vaccine , based on Vical's proprietary DNA delivery technology, was
co-developed at the National Institute of Allergy and Infectious Diseases'
(NIAID) Vaccine Research Center (VRC) and at Vical.

About West Nile Virus
West Nile virus has been an increasing seasonal threat in the United
States over the past several years, causing growing numbers of cases in birds,
horses, and humans each summer.A.

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Vical's President and Chief Executive Officer, Vijay B.
Conventional vaccines , using whole killed West Nile virus, are available
for horses and for some species of birds. These forward-looking statements
represent the company's judgment as of the date of this release.vical . Dr. Dr.

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"
The WNV vaccine encodes two key surface proteins of the West Nile virus. joined LineaGen in 2002 as Chief Operating Officer
and Vice President for Corporate Development. He is a Governor Appointee to
the Steering Committee of the Utah Technology Industry Commission and is
active in the Utah chapter of the Licensing Executive Society. in Biology from Colby College and his Ph.

About LineaGen
LineaGen Research Corporation is a biotechnology research and licensing
company that utilizes a powerful population genetics discovery platform to
identify and validate biomarkers , coordinate clinical trials, and identify
health-promoting and disease-causing genetic factors.

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Samant , said, "We
are pleased with the continued progress under our collaboration with the NIH,
with four vaccine programs that have now advanced to human clinical testing. Most
West Nile virus deaths are caused by encephalitis, a severe swelling of the
brain, or meningitis, a severe swelling of the membrane surrounding the brain
and spinal cord.D. has been promoted to President of
the company .

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West Nile Virus DNA Vaccine Enters Human Trial

P. as Director, Strategic Development. Dr.

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Additional information on Vical is
available at http://www.

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Dr.com

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Paul is
registered to practice before the United States Patent and Trademark Office.