The PillCam (TM) SB
capsule is the only naturally ingested method for direct visualization of the
entire small intestine. The
meeting showcases approximately 5,000 abstracts and hundreds of lectures on
the latest advances in GI research, medicine and technology., Pregnant women present during the
September 11 World Trade Center collapse have passed on markers of Post
Traumatic Stress Disorder (PTSD) to their unborn babies through
transgenerational transmission.
"The findings suggest that mechanisms for transgenerational transmission
of biologic effects of trauma may have to do with very early parent -child
attachments," says Dr. Founded
in 1916, The Endocrine Society is the world's oldest, largest , and most active
organization devoted to research on hormones, and the clinical practice of
endocrinology .

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Given Imaging Announces 85 Capsule Endoscopy Studies to Be Presented at Digestive Disease Week 2005

The company is developing a complete line of
PillCam(TM) video capsules for detecting disorders of the gastrointestinal
tract. Since lower cortisol levels in
relation to maternal PTSD were most apparent in babies born to mothers who
were in their third trimester on 9/11, the data implicate the possibility of
in utero effects as contributors to a putative biological risk factor for
PTSD . Today, The Endocrine Society's
membership consists of over 12,000 scientists, physicians, educators , nurses
and students, in more than 80 countries.

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YOQNEAM, Israel, Given Imaging
(Nasdaq: GIVN ) announced today that 85 abstracts on capsule endoscopy will be
presented at this year's Digestive Disease Week(R) 2005 (DDW(R)) in Chicago
May 14 - 19 at McCormick Place.
Additional capsules for visualization of the stomach and colon are under
development. For more information, visit http:/ /www.com.

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Similar to the PillCam SB
and PillCam ESO, PillCam COLON is a naturally ingested, video capsule that
will leverage the RAPID platform. The study will be published online today in The Journal of
Clinical Endocrinology + Metabolism, one of the four journals produced by The
Endocrine Society .

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The company's technology platform is the Given(R) Diagnostic System,
featuring the PillCam video capsule, a disposable, miniature video camera
contained in a capsule, which is ingested by the patient . Together, these members represent all
basic, applied, and clinical interests in endocrinology. To learn more about the Society, and the
field of endocrinology, visit the Society's web site at
http: //www.

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diagnostics and the number of studies
presented this year confirms PillCam's use as a primary diagnostic tool for an
ever increasing list of indications," said Gavriel D.org for additional
information .

Moreover, approximately one year after birth, the babies of
mothers who had developed PTSD symptoms had significantly lower cortisol
levels compared to that in babies of mothers who developed only minimal
symptoms.

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Given Imaging will host booth number 1024.ddw.

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l. The Endocrine Society
is based in Chevy Chase, Maryland.

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"Since launching the PillCam platform four years ago we have established a
large footprint in the field of G. Robynne Chutkan and Blair Lewis - Monday, May
16th from 8:15am - 9:15am, McCormick Place - E353C

In addition, at DDW Given Imaging will commence the enrollment of sites
for initial clinical trials of PillCam(TM) COLON.givenimaging .

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"

JCE+M is one of four journals published by The Endocrine Society.

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On May 2nd, the Company announced its plans
to submit the product for clearance by the U. Visit the
Digestive Disease Week web site at http://www.

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About Digestive Disease Week
Digestive Disease Week (DDW) is the largest international gathering of
physicians, researchers and academics in the fields of gastroenterology,
hepatology, endoscopy and gastrointestinal surgery. Those forward-
looking statements are not guarantees of future performance and actual results
could differ materially from our current expectations as a result of numerous
factors, including but not limited to the following: changes in regulatory
environment, our success in implementing our sales, marketing and
manufacturing plan, protection and validity of patents and other intellectual
property rights, the impact of currency exchange rates, the effect of
competition by other companies, the outcome of future litigation, the
reimbursement policies for our product from healthcare payors, quarterly
variations in operating results, the possibility of armed conflict or civil or
military unrest in Israel and other risks disclosed in our filings with the
U. CHEVY CHASE, Md. Mothers who experienced symptoms of PTSD in response to 9/11
had lower cortisol levels compared to mothers who did not develop this
condition .

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About Given Imaging
Given Imaging is redefining gastrointestinal diagnosis by developing ,
producing and marketing innovative, patient-friendly products for detecting
gastrointestinal disorders.D.

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org

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(Logo: http://www.com/cgi-bin/prnh/20050405/ENDOLOGO )
Previous studies led researchers to believe that reduced cortisol levels
observed in the adult children of Holocaust survivors could be attributed to
mostly environmental factors, such as the stress of living with a parent who
is depressed or anxious, or the experience of vicarious traumatization based
on hearing stories of how parents suffered, rather than a 'transmitted'
biological trait.

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Speakers include Drs.S.

Babies Show Ripple Effects of Mothers' Stress from 9/11 Trauma

"In the current study, reduced stress hormone levels were
observed in infants, suggesting a larger role for very early environmental,
genetic, or genetic-environmental interactions than previously thought,"
explains Rachel Yehuda, Ph.endo-society.

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Securities Exchange Commission.

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Given Imaging's headquarters, manufacturing and R+D facilities
are located in Yoqneam, Israel; it has direct sales and marketing operations
in the United States, Germany and France, and local offices in Japan, Spain
and Australia. Jointly sponsored by the
American Association for the Study of Liver Diseases (AASLD), the American
Gastroenterological Association (AGA), the American Society for
Gastrointestinal Endoscopy (ASGE) and the Society for Surgery of the
Alimentary Tract (SSAT), DDW takes place May 14 - 19, 2005 in Chicago.S. This decrease in cortisol levels among the infants was similar to
their mothers' hormonal response to PTSD.

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newscom . Endocrinologists are specially trained doctors who diagnose,
treat and conduct basic and clinical research on complex hormonal disorders
such as diabetes, thyroid disease, osteoporosis, obesity, hypertension,
cholesterol and reproductive disorders.

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The PillCam(TM) ESO video capsule, which provides visual
examination of the esophagus, has been cleared for marketing by the FDA.

This press release contains forward-looking statements about Given
Imaging, including projections about our business, our future revenues and our
future profitability, within the meaning of Section 27A of the Securities Act
of 1933 and Section 21E of the Securities Exchange Act of 1934. For example,
statements in the future tense, words such as "anticipates," "estimates,"
"expects," "intends," "plans," "believes ," and words and terms of similar
substance used in connection with any discussion of future operating or
financial performance identify such forward-looking statements.
Scientists at Mount Sinai School of Medicine and the University of
Edinburgh studied the relationship between maternal posttraumatic stress
syndrome disorder (PTSD) symptoms and salivary cortisol levels in 38 women and
their infants .

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Food and Drug Administration
and launch it in Europe in 2006. Yehuda, "and possibly even in utero effects related to
cortisol programming.

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"The data also indicates that
PillCam SB is clearly the gold standard for mucosal imaging of the entire
small bowel and that our newest capsule endoscope , PillCam ESO, presents a
tremendous opportunity for less invasive imaging of the esophagus., principal investigator of the study.

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Meron, president and
chief executive officer of Given Imaging."
Clinical data studies to be presented on capsule endoscopy include:

Celiac Disease

* "Evaluation of capsule Endoscopy in Celiac disease Patients with
Ongoing symptoms on a Gluten-Free Diet- A prospective Blinded European
Multicenter trial" (Presentation 547) - Tuesday, May 17th at 2:30pm -
2:45pm, McCormick Place - E450A

* "Video Capsule Endoscopy for the Diagnosis of Celiac Disease:
Preliminary Results From a Multicenter International Study"
(Presentation 548) - Tuesday, May 17th at 2:45pm - 3:00pm, McCormick
Place - E450A

* "Capsule Endoscopy in Evaluation of Patients with Celiac Disease"
(Abstract M1322) - Monday, May 16th from 8am - 5pm, McCormick Place -
Hall E

Chronic Liver Disease

* "The Clinical Utility of Wireless Capsule Endoscopy in Patients with
Cirrhosis, Varices, and Anemia" (Abstract S1619) - Sunday, May 15th
from 8am - 5pm, McCormick Place - Hall E

Bleeding

* "Capsule Endoscopy for Acute Gastrointestinal Bleeding " (Presentation
SP674) - Tuesday, May 17th at 2:15pm, McCormick Place - E353AB

Small Bowel Tumors

* "Diagnosis and Outcome of Small Bowel Tumors Found by Capsule
Endoscopy: A Three Center Australian Experience" (Abstract M1309) --
Monday, May 16th from 8am - 5pm , McCormick Place - Hall E

* "Diagnostic Value of Video Capsule Endoscopy in Carcinoid Tumors "
(Abstract M1406) -- Monday, May 16th from 8am - 5pm, McCormick Place -
Hall E

* "Intestinal Tumors: Frequently Revealed by An Obscure Digestive
Bleeding (ODB) and More Easily Diagnosed by Capsule Endoscopy (VCE)"
(Abstract M1320) -- Monday, May 16th from 8am - 5pm, McCormick Place -
Hall E

Crohn's

* Videocapsule Endoscopy versus Colonoscopy for the Diagnosis of
PostSurgical Recurrence in Crohn's disease (CD): A pilot study
(Abstract M1307) -- Monday, May 16th from 8am - 5pm, McCormick Place -
Hall E

Additional Capsule Endoscopy Presentations

* "ASGE Poster Grand Rounds on Capsule Endoscopy" (Presentation SP313e). It is currently marketed in the United States and in
more than 60 other countries and has benefited more than 200,000 patients
worldwide. The findings strengthen the evidence for in
utero or early life risk factors for the later development of adult mental or
physical disorders.

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