"
"Collaborations
and CSR programs were initiated with the FDA for
Salmonella and E.D."
"We continue to expect
deployment of BDS units to be completed in all 282
USPS processing centers by the end of this year
.
The Company moved expeditiously to notify customers and has not received any
indication of adverse
patient events.e.
elephantiasis rickettsial
Previous
guidance was for gross margin on product sales to be in the range of 45
% to
49%.0 million to
$14.26
per share.com, through August 4, 2006.
CONTACTS:
At the Company:
John L.aasld.rickettsial encephalitis
Product sales for the quarter ended June 30, 2005
increased 93% to
approximately $20. The decline in gross
margin on product sales for the six months
ended June 30, 2005 as compared to
the corresponding prior year period was due primarily to the amortization
of
up front license fees and higher ongoing royalty costs associated with the
Company's patent
license agreements entered into with Applera Corporation and
F. pestis, F.
After the live
webcast, the call will remain available on Cepheid's
website, http://www.
The World Guide
to Pharmaceutical Industry CD-ROM product is based on CD-
ROM technology which includes smart database
structure, find and sort options,
internet and email interactivity.esophagus danlos
3 million for the
corresponding
prior year period while total revenues for the six months ended
June 30, 2005 increased 121% to approximately
$41. pestis, F.
Conference Call Information
Cepheid's CEO, John Bishop, and Senior
V. The
replay will be available after 6:30 pm (Eastern).
"This Workshop will build upon
the work of
the Foundation's previous scientific conferences and the significant recent
advances
in the understanding of AAT Deficiency.
(Logo: http://www. To reflect changes we have
included
a separate list of companies who have either filed for bankruptcy,
undergone M+A etc. Hence, the
3rd
Edition of World Guide to Pharmaceutical Industry brings important information
closer to you
from one source.encephalitis pontine
, Cepheid (Nasdaq: CPHD)
today announced financial results for the quarter and six
months ended June
30, 2005.0 million from approximately
$17. These releases bring the total number
of ASR's currently available
from the Company to 10.D. Bishop John R., D.researchandmarkets
.endocarditis erythema
Bishop
stated:
"Work is continuing on our BCR/ABL ASR product for use on the GeneXpert
(R)
system and we continue to expect to initiate product shipments in the second
half of this year
. The key issue has been to insure optimization of
the test sensitivity in the GeneXpert system and
to simultaneously make
available a product with the same level of sensitivity for our existing
SmartCycler
customers.
tularensis, Smallpox, Burkolderia, Brucella, Ebola, Marburg, CCHF and VEE."
"We
also recently had our first Customer Corrective Action Notice
involving a software bug associated
with our SmartCycler Diagnostic software.33 per share based on actual weighted average
shares outstanding
of 42. A replay of the conference
call will be available at 800-405-2236 (domestic) or 303-590-3000
(international) through August 11, 2005; the conference ID is 11034949.09) $(0.17) $(0.D
.
The objectives of the conference are to understand the molecular biology
of protein folding
, the role of the protein degradation system, and the
consequences of misfolding of specific proteins
seen in several clinical
disorders.
The Alpha-1 Foundation is dedicated to providing the
leadership and
resources that will result in increased research, improved health, worldwide
detection
and a cure for Alpha-1 Antitrypsin Deficiency (Alpha-1). Whether you are a CEO, business
developer
, in/out licensing officer, venture capitalist, consultant etc.danlos elephantiasis
The increase in product
sales for
the quarter and six months ended June 30, 2005 as compared to the
corresponding prior year periods
was primarily due to a 371% and 459% increase
in reagent and disposable sales, respectively. Gross
margin on product sales for
the full year 2005 is expected to be in the range of 43% to 45%. In this
regard, we
recently received an Authorization Letter from Northrop Grumman for the
purchase of
2. We do not expect this customer
corrective action to have any material financial impact to the
Company."
"We reaffirm that we expect our 2005 product sales to be in the range of
$80.0 million
or $0.
All forward-looking statements and reasons why results might differ
included in this
release are made as of the date of this press release, based
on information currently available to
Cepheid, and Cepheid assumes no
obligation to update any such forward-looking statement or reasons
why results
might differ.20)
Shares used in computing
basic and diluted net
loss per share 42,465 41,713 42,355 40,211
CEPHEID
CONDENSED CONSOLIDATED BALANCE SHEETS
(in thousands)
June
30, December 31,
2005 2004
(unaudited) (1)
ASSETS
Current assets:
Cash and cash equivalents $18,448 $23
,189
Marketable securities 34,000 34,250
Accounts receivable
12,570 14,584
Inventory
8,298 6,544
Prepaid expenses and other current assets 1,314 402
Total current assets 74,630 78,969
Property and equipment
, net 12,042 9,756
Restricted cash
688 688
Intangible assets, net 29,708 30,902
Total assets $117,068 $120,315
LIABILITIES
AND SHAREHOLDERS' EQUITY
Current liabilities:
Accounts payable
$12,930 $ 8,074
Accrued compensation 2,594 2
,836
Accrued royalties 2,414 2,113
Accrued other
liabilities 4,103 4,517
Current portion of deferred revenue
2,853 3,847
Current portion of license fee payable 10,683 10
,476
Current portion of equipment financing 2,061 1,889
Total current
liabilities 37,638 33,752
Long term portion of deferred revenue
5,238 6,190
Long term portion of licensing fees payable 6,700
8,561
Equipment financing, less current portion 2,358 1,604
Line of credit
4,000 4,000
Deferred rent
654 599
Commitments
Shareholders' equity:
Preferred stock
-- --
Common stock
153,935 152,136
Additional paid-in capital 7,519 7,517
Accumulated other comprehensive loss 26 (137)
Accumulated deficit
(101,000) (93,907)
Total shareholders' equity
60,480 65,609
Total liabilities and shareholders' equity $117,068 $120,315
(1) The balance sheet at December 31, 2004 has been derived from the
Company
's audited financial Statements, which are included in the
Company's 2004 Annual Report on
Form 10-K filed with the Securities
and Exchange Commission.fevers esophagus
5 million for the
corresponding
prior year period while product sales for the six months ended
June 30, 2005 increased 128% to approximately
$39.1 million for the corresponding prior year period.
Total revenues for the quarter ended June
30, 2005 increased 89% to
approximately $21.17 per
share, respectively, compared to a net loss
of approximately $3.20 per share, respectively, for the
corresponding prior year periods.
"The Company is continuing to show progress in developing the individual
segments of our overall
business plan. This was achieved using our patented testing system
that includes our closed cartridge
, with integrated automated sample
processing.
2005 Outlook
Commenting on Cepheid
's outlook for the remainder of 2005, Mr."
"Research also continues on a GeneXpert version of
MRSA and a second
generation MRSA test for the SmartCycler system. The call will be simultaneously
broadcast over the Internet.com for more
information.
The AASLD is a leading organization
of scientists and healthcare
professionals committed to preventing and curing liver disease.org
)
Contact: Marlene Erven
+1-305-567-9888, ext.
World Guide to Pharmaceutical
Industry was created for professionals
within the industry and for those with particular interest
of the
pharmaceutical industry, i.infectiosum endocarditis
Persing is
a noted authority in the field of infectious diseases
and he brings a unique
combination of practical clinical experience along with a familiarity of
industry
research and development models, which should immediately benefit the
team and our programs in the
Clinical, Biothreat and Industrial markets,"
stated John Bishop, Cepheid's CEO. Development of our
initial FDA product for detection of
Group B Strep (GBS) continues on the GeneXpert system along
with a second
generation version of GBS on the SmartCycler(R) system. Our product for the detection
of Enterovirus is also
expected to enter clinical trials this year. Interested participants and investors
may access
the teleconference call by dialing 800-366-7417 (domestic) or 303-262-2141
(international
)., the 2004 Nobel Prize
Winner in Chemistry, will be a featured presenter," says John Walsh, President
and CEO of the Alpha-1 Foundation.ollier danlos
The increase in total revenue for
both the quarter and six
months ended June 30, 2005 as compared to the
corresponding prior year period was due primarily to
the increase in product
sales.4 million for the quarter and
six months ended June 30, 2005 was
primarily derived from the amortization of
up-front license fees in connection with the Company's
collaboration with
bioMerieux. However,
given the near-term impact on our manufacturing gross
margins, we are
increasing our expected 2005 net loss to be in the range of $12.5 million as of June
30, 2005.liverfoundation.encopresis filariasis
0 million from $18.7 million, or
$0. In addition, a new general use PCR
master mix product
was released for use in both our ASR and Industrial markets. At this time over
800 BDS units have been installed. tularensis, Smallpox, Burkolderia,
and Brucella; a 10 agent array
cartridge including anthrax, Y. We
expect to make significant progress in resolving these issues
by the end of
this year.0 million to $84.P.
This press release contains forward-looking
statements that are not purely
historical regarding Cepheid's or its management's intentions, beliefs
,
expectations and strategies for the future, including those relating to future
product releases
, product performance, future revenues, future margins, future
net losses and the status of the USPS
BDS program. 211
abscess encopresis
7 million and $1. The gross margin percentage on product sales for the quarter
ended
June 30, 2005 was consistent at 42% when compared to the corresponding prior
year period
and decreased to 43% for the six months ended June 30, 2005 as
compared to 47% for the corresponding
prior year period.
Net loss for the quarter and six months ended June 30, 2005 was
approximately
$3. Previous guidance was
an expected 2005 net loss of $9. Our net loss projections do not include
any stock compensation
expense associated with SFAS 123R for which mandatory implementation has been
delayed until January 1, 2006 by the Securities and Exchange Commission."
As of June 30
, 2005, the Company had $52.org )
The American Liver Foundation is the nation's leading nonprofit
organization promoting liver health and disease prevention. Companies are described by all their
targeted
therapeutic areas (see list below), short profile, contact information
(address, phone
, fax), web address and email.prune elephantiasis
09 per share and $7. This result is equivalent to a specificity of
greater
than 99. pestis and F.09) $(0. Other sponsors include the National Institutes of Health --
National
Institute of Diabetes and Digestive and Kidney Diseases, and Office
of Rare Diseases -- and American
Liver Foundation.
"We are pleased that Aaron Ciechanover, M.Sc.org . This brings the total number
of corporate profiles
covered in this product to more than 2,700 from 54 different nations (see list
of nations presented below). Companies
can be further researched on from inside the application
by linking search
queries directly to search engines like Google and PubMed.rickettsial prune
1 million, or $0. We
expect to
simultaneously introduce both products in early 2006 in Europe with subsequent
release
in the United States.filariasis abscess
Gross Margin Dollars on product sales (total product sales less cost of
product sales) for the quarter and six months ended June 30, 2005 increased by
94% and 112%, respectively
as compared to the corresponding prior year
periods. Three ASR's were released during the
second
quarter covering gene expression and bacterial targets.com. Web participants
are encouraged to go
to the web site at least 15 minutes prior to the start of
the call to register, download, and install
any necessary audio software.sluis@cepheid.com
At Financial Relations Board:
Tim Grace Tricia Ross
Media Contact Investor
/Analyst Information
312-640-6667 617-520-7064
tross@financialrelationsboard
. Participants will discuss the current concepts of the molecular
mechanisms responsible for liver
injury in patients with Alpha-1 Antitrypsin
Deficiency.com/cgi-bin/prnh/20040820/RESEARCH )
This exciting world intelligence CD-ROM on pharmaceutical industry has
become better, stronger
and more intelligent in its 3rd Edition.myelinolysis multiforme
coli, Enterococcus, Vibrio, Bacteroides and
the Public Health
Research Institute (PHRI) for Methicillin Resistant Staph
aureus (MRSA) and VRE. Both tests are expected
to be
simultaneously released in 2006. tularensis and
Smallpox; 4 agent viral cartridge including
Ebola, Marburg, Crimean-Congo
hemorrhagic fever (CCHF) and Venezuelan equine encephalitis (VEE);
6 agent
cartridge including anthrax, Y. Early indications are that the Cepheid
tests, utilizing
our licensed Scorpions technology, will be found to be
superior to the competitor products."
"While we continue to make significant progress in product development, we
are also addressing
issues associated with automated high volume production
which have negatively impacted our manufacturing
gross profit margins.0 million, based on anticipated sales for the USPS
program and sales expected
from other existing and new products.4 million in unrestricted cash
and marketable securities.com
CEPHEID
CONDENSED CONSOLIDATED STATEMENTS
OF OPERATIONS
(Unaudited)
(in thousands
, except per share data)
Three Months Ended Six Months Ended
June 30, June 30,
2005 2004 2005 2004
Revenues:
Instrument sales
$7,262 $7,720 $13,621 $ 12,584
Reagent and disposable
sales
12,942 2,749 25,334 4,533
Total Product Sales 20,204
10,469 38,955 17,117
Contract revenues 743 807 1,390
1,420
Grant and government
sponsored research
revenues
437 9 605 9
Total revenues 21,384 11,285
40,950 18,546
Operating costs and
expenses:
Cost of product sales
11,743 6,113 22,017 9,131
Collaboration profit
sharing
3,602 607 7,208 1,032
Research and development 4,538
3,864 9,044 7,494
Selling, general and
administrative
5,036 4,434 9,591 7,501
Expense for patent
related matter
-- -- -- 1,264
Total costs and
operating expenses
24,919 15,018 47,860 26,422
Loss from operations (3,535) (3,733
) (6,910) (7,876)
Other income
(expenses), net (100) 22
(183) 18
Net loss $(3,635) $(3,711) $(7,093) $ (7,858
)
Basic and diluted net
loss per share $(0.danlos eosinophilia
However, we will be realizing
less gross profit dollars on product
sales than we had previously expected in the near term. Sluis
CEO, Cepheid CFO, Cepheid
408-541-4191
408-541-4191
john. David Perlmutter and Bruce Trapnell. This conference will highlight studies
and future research
opportunities which may help to define molecular approaches underway to
develop
effective therapies to treat the liver manifestations of disorders
involving protein misfolding.
( http://www.newscom. All companies are provided with links, which
connect you directly to the
company webpage for further research.epidural ollier
Cepheid Reports Second Quarter 2005 Results
Total Revenues
Increase by 89% Driven by 93% Increase in Product Sales
Gross Margin Dollars on Product
Sales Increase by 94%
SUNNYVALE, Calif. Two additional
ASR's for bacterial targets were
released subsequent to the close of the
quarter.9999%. Coli and
Enterococcus against other competitors
. and CFO, John Sluis will host
a conference call today at 4:30 pm (Eastern) to discuss Cepheid's
financial
results, business highlights and outlook. Founded in 1996, the company
is commercializing
its technology and products worldwide for research,
medical, and industrial applications requiring
assessment of the human genome,
infectious disease and biothreat agents.cepheid.
-- Jump
start competitive intelligence operations
-- Excellent starting point for world wide benchmarking
-- Compare portfolio and therapy focus with your peers
-- Speed up pro-active in-/outlicensing
strategy work
-- Track companies over time using search engines
-- Show investors/board
/management that you are right on top of industry
development
For more information
visit
http://www.pontine eosinophilia
As we have previously
discussed, we expect to continue to supply GeneXpert anthrax
test cartridges
to the USPS for use in the installed base of BDS units.0 million or $0.cepheid.,
Director, Pediatric Liver Care Center, Cincinnati Children's
Hospital Medical Center. ( http://www
.Research and Markets: Introducing The World Guide to Pharmaceutical Industry 2005
myelinolysis filariasis
Dr. We
have
also announced our development plans for an expanded biothreat product
menu, which is expected to
include the following cartridge configurations in
sequential order: 3 agent cartridge including anthrax
, Y.
tularensis; 4 agent cartridge including anthrax, Y.21 to $0., is a leading
developer, manufacturer
and marketer of fully integrated systems that enable
genetic assessment when and where it is needed
. Because such statements
deal with future events, they are subject to various risks and uncertainties
,
and actual results could differ materially from the company's current
expectations.Scientific
Meeting on Alpha-1 Antitrypsin Deficiency and Other Liver Diseases Caused by Aggregated Proteins
D.alphaone.com/reports/c15309
Laura Wood
Senior Manager
Research and Markets
press@researchandmarkets.eosinophilia sturge
5 million
for the corresponding prior year period. coli O157:H7
/STEC, the University of North Carolina for
recreational water testing of E., Ph.28 to $0. There will
also be a live webcast of the call on the Investor
Relations section of Cepheid's web site at http:
//www.cepheid.prune fevers
6 million, or $0.09 per share and $7. pestis, F. In response to market
demand, we are
expanding what was previously the Life Science market to a
broader Industrial market, which will
encompass Food, Agricultural and
Environmental testing in addition to research use generally associated
with
the Life Science market. As a part of this program, we recently participated
in a head-to
-head third party evaluation of water tests for E.
About Cepheid
Cepheid (Nasdaq: CPHD
), based in Sunnyvale, Calif. Factors that could cause actual results to differ materially
include
risks and uncertainties such as those relating to: the scope and
timing of actual USPS funding and
deployment of the BDS; the occurrence of
delays with respect to the BDS, the rate of environmental
testing using the
BDS conducted by the USPS, which will affect the amount of consumable products
sold, and whether the BDS performs to specifications; development and
manufacturing problems,
including with respect to the GeneXpert system and
reagents; the need for additional licenses for
new tests and other products
and the terms of such licenses; our ability to complete clinical trials
successfully in a timely manner for products to be marketed in clinical
markets; our ability to
successfully commercialize our stand-alone GeneXpert
system; lengthy sales cycles in certain markets;
the performance and market
acceptance of new products; sufficient customer demand in the Industrial
markets; our reliance on distributors to market, sell and support our
products; the occurrence
of unforeseen expenditures, acquisitions or other
transactions; our success in increasing direct
sales; the impact of
competitive products and pricing; our ability to manage geographically-
dispersed
operations; and underlying market conditions worldwide.
Balistreri, M. Dr Balistreri is conference
co-director with
Drs.com/reports/c15309 ) has announced the addition
of World Guide to Pharmaceutical
Industry 2005, 3rd ED to their offering.encephalitis hemorrhagic
4 million compared to approximately $11."
"The biothreat
program with the United States Postal Service (USPS)
continues to move forward with installation
of Biohazard Detection Systems
(BDS). These water testing products are expected
to be released
for environmental recreational water testing before the end of
2005. See http://www.
"This
is a novel gathering of scientists and clinicians in related areas
to focus on the important emerging
topic of the molecular pathogenesis and
therapeutic approaches to the hepatotoxicity associated with
the inherited
metabolic disorder Alpha-1 Antitrypsin Deficiency," says William F." For a full agenda
and
information, visit: http://www. DUBLIN, Ireland, Research and Markets
(http://www. you
will find World Guide to Pharmaceutical Industry useful to locate M+A
candidates, customers, collaboration
partners, competitors etc.com
Fax: +353 1 4100 980
filariasis tremor
Contract revenue of $0.9 million
, or $0. In addition, a
significant testing milestone has been passed with over 1,000,000 tests now
having been run with no false positives while simultaneously maintaining a
very high level of
sensitivity."
"Subsequent to the close of the quarter, we made a significant addition to
the
management team with the appointment of David Persing M.,
currently a member of the Company's Board
of Directors, to the position of
Executive Vice President, Chief Medical and Technical Officer.3
million anthrax cartridges to be delivered over a 14 month
period commencing in August of 2005 and
running through September of 2006."
"Our market focus will continue to be in the Clinical Genetic
Assessment
market, along with the Biothreat and Industrial markets.researchandmarkets. The 3rd
Edition
of World Guide to Pharmaceutical Industry has not only been updated
but it has also been strengthened
with over 400 new young biopharmaceutical
companies world wide. investors, trade organizations, and
associated
industry to that of pharmaceutical industry.
Therapeutic Areas Covered:
-- Addiction
-- Autoimmune/Inflammation
-- Biomaterial/Skin/Wound/ Blood products
-- Cancer
-- Cardiovascular
-- Dermatology
-- Gastroenterology
-- Genetic diseases
-- Growth hormone therapy
-- Hormone replacement therapy
-- Infectious diseases
-- Metabolic diseases
-- Neurological disorders
-- Odontology
-- Ophthalmic
-- Pain
-- Reproductive
-- Respiratory diseases
-- Urogenital Diseases
This report offers the following:
-- Find competitors
, collaborations partners, M+A candidates etc.erythema eosinophilia
2 million from approximately $10. Hoffman-La Roche Ltd
in the second and third quarter of 2004 as well as one
time favorable pricing achieved in the first
quarter of 2004 which did not
occur in the six months ended June 30, 2005.0 million to $11. Readers
should also refer to the section entitled "Risk Factors" in Cepheid's Annual
Report on Form 10
-K for 2004 and in its most recent quarterly report on Form
10-Q, each filed with the Securities and
Exchange Commission. Experts From Around the World to Convene in Atlanta
MIAMI
, The Alpha-1 Foundation, in conjunction with
the American Association for the Study of Liver Diseases
(AASLD) has organized
a Basic Research Single Topic Conference on Alpha-1 Antitrypsin Deficiency
and
Other Liver Diseases Caused by Aggregated Proteins on January 26-28, in
Atlanta, GA. Alpha
-1 is
a genetic disorder that can cause liver and lung disease in children and
adults.ollier endocarditis
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