The study also looked at the assumed association between autoimmune
diseases such as lupus, diabetes, rheumatoid arthritis and Addison 's disease
and autism in the children of mothers with those conditions. Asthma and allergies in
expectant mothers were associated with 50% increase in risk of autism in their
children."

About Numax
Numax is a humanized MAb currently being developed to potentially prevent
serious lower respiratory tract disease caused by RSV in pediatric patients at
high risk of RSV disease.

Additional Synagis Information
Synagis is marketed for the prevention of serious lower respiratory tract
disease caused by RSV in pediatric patients at high risk of RSV disease, which
is prominent in the Northern Hemisphere during the winter months. Synagis was approved in 1998 by the U. For more information, visit
the company's website at http://www.com.

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This new
agreement provides MedImmune with a larger portion of the economics from our
RSV franchise outside of the U., and longer term , provides us with the
opportunity to participate directly in the commercialization of Numax outside
the United States. Food and Drug
Administration (FDA), in 1999, by the European Medicines Evaluation Agency,
and in 2002, by the Japanese Ministry of Health, Labor and Welfare.

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, Asthma or allergies in an
expectant mother may increase the likelihood that her child will exhibit
symptoms of autism , according to a Kaiser Permanente study featured in the
Archives of Pediatrics and Adolescent Medicine 's February issue.
Nationwide, Kaiser Permanente includes approximately 138,000 technical,
administrative and clerical employees and caregivers, and more than
11,000 physicians representing all specialties .


, MedImmune, Inc. For full prescribing information for Synagis, see the company's
website at http://www.

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The study looked at more than 88,000 children born within the Kaiser
Permanente population of Northern California between January 1995 and June
1999. Croen and her associates at Kaiser Permanente, the Department of
Health Services in Oakland, CA, and the University of California at Davis
found no association between autoimmune diseases in pregnant women and an
increased risk of autism in their children, with the exception of psoriasis,
which was associated with a doubling of risk.medimmune. There can be no assurance that such development efforts will
succeed, that Numax will receive required regulatory clearance or that, even
if such regulatory clearance is received , there will be any significant market
for Numax or that Numax will ultimately achieve commercial success.


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Even with the increase in
risk, Dr. From that group, 420 children between 3 and 7 years old were identified
with diagnoses of autism. Founded in
1945, it is a not-for -profit, group practice prepayment program with
headquarters in Oakland, California., Kaiser
Foundation Hospitals and their subsidiaries, and the for-profit Permanente
Medical Groups. The Numax
comparative Phase 3 trial is designed to assess if the increased potency seen
in preclinical studies can be translated into better efficacy against lower
respiratory tract illness in high-risk children and to assess the effect of
Numax on upper respiratory tract disease, such as otitis media.S.medimmune.

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"What we did
find was a two-fold increase in autism among children of asthmatic mothers or
women with allergies, particularly if their symptoms were medically diagnosed
in the second trimester of pregnancy . - MedImmune Has Co-Promotion Rights for Numax
in Seven Ex-U.com.

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2 million members in 9 states and the District of Columbia.

MedImmune Expands Ex-U.S. Distribution Agreement with Abbott for Monoclonal Antibodies Against RSV

Markets -

GAITHERSBURG, Md . With approximately 2,000 employees
worldwide, MedImmune is headquartered in Maryland.

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Those children were compared with a control group,
children without a diagnosis of autism spectrum disorders. Kaiser Permanente serves the health care
needs of 8.

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Kaiser Permanente has research offices in California , Oregon, Hawaii,
Georgia, Colorado, Maryland, and Ohio.," said Holger Liepmann, senior vice president , International Operations,
Abbott.

Information, support and advice concerning conditions and diseases in children, ranging in age from newborn to twenty-one years old.

enuresis jaundice

distribution
agreement with Abbott for monoclonal antibodies (MAb) against respiratory
syncytial virus (RSV).
"Abbott has been our exclusive distributor of Synagis outside of the U. "Expanding our relationship with Abbott to include Numax enables
us to build on the success they are already having with Synagis.

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This announcement contains, in addition to historical information, certain
forward-looking statements that involve risks and uncertainties.

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Croen cautions that the risk of autism is still small, less than 1%
even in children of women with asthma during pregnancy.
Dr.
(Nasdaq: MEDI) announced today that it has amended its ex-U.

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"
This association between a mother's asthma and allergies and a child 's
autism has not been reported in the medical literature previously, says Dr.S. Such
statements reflect management's current views and are based on certain
assumptions.

foetal bedwetting


"With the exception of psoriasis, we did not find an association between
autoimmune diseases in mothers and autism," says study author Lisa A.S.S. Additionally, Abbott will continue to distribute and market
Synagis (R) (palivizumab), MedImmune's first-generation anti-RSV MAb. is likely to be dependent
in large part to commercialization efforts that are not within MedImmune's
direct control.

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and, since its launch in 1999, the product has experienced significant
growth," said David M.S. Children born prematurely as well as
those with chronic lung disease or congenital heart disease are at highest
risk of severe disease and hospitalization due to RSV.

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S. label for Synagis for use in young children with
hemodynamically significant congenital heart disease at risk of RSV disease.

bedwetting tonsil

Today
it encompasses the not-for-profit Kaiser Foundation Health Plan, Inc. "Furthermore, this agreement demonstrates Abbott's continued long -
term commitment to bringing advanced RSV prevention options to physicians and
patients. Synagis is a
humanized MAb given through a simple intramuscular injection once a month
during the RSV season.

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To date, Synagis has been approved in 62 countries, including the United
States.

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Mother 's Asthma or Allergies May Increase Risk of Autism in Her Children

Kaiser Permanente Research Shows Autoimmune Diseases Once Considered Risk
Factors Are Not Associated With Autism in Children

OAKLAND, Calif.
Croen, and requires replication in further studies.S."
"We're pleased to build on the success we've realized with Synagis and
this agreement expands and extends Abbott's RSV franchise outside of the
U.

oncall abnormality

Results of research conducted by
Kaiser Permanente physicians and investigators have been published in the
Journal of the American Medical Association , the New England Journal of
Medicine, the Permanente Journal, the American Journal of Public Health ,
Pediatrics, and other clinical journals. As a
part of the amendment, MedImmune has the option to co-promote Numax with
Abbott in up to seven countries outside of the United States. As previously
stated, MedImmune intends to market and sell Numax on its own in the United
States. Mott, chief executive officer and president of
MedImmune.
Approximately one-half of all infants are infected with RSV during the first
year of life, and nearly all children have been infected at least once by the
time they reach their second birthday.

About MedImmune
MedImmune strives to provide better medicines to patients, new medical
options for physicians, rewarding careers to employees, and increased value to
shareholders. Dedicated to advancing science and medicine to help people live
better lives, the company is focused on the areas of infectious diseases,
cancer and inflammatory diseases.S.

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About RSV
RSV is the most common respiratory infection in infancy or childhood.

sids enuresis

Croen,
PhD, of Kaiser Permanente's Division of Research in Oakland, CA. In 2003,
the FDA expanded the U.S.

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Kaiser Permanente is America's leading integrated health plan . In November 2004, MedImmune initiated a pivotal
worldwide Phase 3 study comparing the safety and efficacy of Numax in reducing
RSV disease in high-risk infants to that of Synagis, the current standard of
care for reducing RSV hospitalizations in this population. In particular, in addition to risks related to product
development, regulatory approval, manufacturing and commercialization
discussed in MedImmune's filings with the U.

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Under the amended agreement, Abbott will distribute
and market Numax(TM), MedImmune's investigational second-generation anti-RSV
MAb currently in Phase 3 development , upon approval outside of the United
States. Securities and Exchange
Commission, the success of Numax outside of the U.

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