Turns out High School and College Kids Are Actually Pretty Happy

NEW YORK, While teen angst and the struggles of
adolescence is what grabs the headlines, it turns out that members of Gen Y
are generally happy, with 67% of 15-22 year rating themselves as happy or very
happy most of the time according to the Bolt. This differential is reduced to 13% for 18-22 year olds (58% vs . HPV DNA was found to be present in a higher
percentage of cancer cases than initially assumed based on prior studies.
"In the long run, the MassARRAY technology might complement the use of the
Pap smear, a traditional screening method for cervical dysplasia," stated Andi
Braun, M.

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This difference is less pronounced as girls get older.

About Bolt Research
Bolt Lab(TM ) has built an opt-in research panel of over 1 million active
members who are eager to participate in surveys.ascentiabiomedical.

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Bolt Releases First Survey on Youth Happiness

15-17 year olds find friendships
moderately more important than 18-22 year olds. Our ongoing and trusted
relationship with our members result in high-quality responses that are open
and honest.

James Clagett , President and CEO of Ascentia, said, "We are pleased
and excited about these early findings in the mouse model which is a
clinically relevant model of the human breast cancer.D.com.

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While being in a relationship was the third
most important contributor to male happiness, being in a relationship ranked
as only the fifth most important factor for happiness among females. Drs. In the U.

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Ascentia 's scientific
team plans to quickly conduct further testing of the lead compound for cancer
treatment in the effort to file it as an Investigational New Drug (IND) with
the FDA. The study
entitled "Sensitive detection of human papilloma virus in cervical, head/ neck
and schistosomiasis-associated bladder malignancies," was carried out by a
multi-center consortium of investigators headed by Professor David Kurnit of
the University of Michigan."
Scientists tested for the presence of HPV in serum and/or peripheral blood
fraction (PBF) of individuals with cervical dysplasia, cervical cancer ,
head/neck cancer or a form of bladder cancer resulting from a parasitic
infection.

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That finding is counter to beliefs in
mainstream culture that females feel the need to be in a relationship while
men prefer to play the field.

About Bolt
Bolt is a media company that brings together 4 million high school and
college kids each month at Bolt. At Bolt, our business is helping young people find each other
and express themselves, and enabling brands to connect with our members. Keith Knutson (Mayo Clinic), an internationally recognized oncology
researcher and consultant and member of Ascentia's Scientific Advisory Board
who will spearhead Ascentia's oncology research, discusses the potential use
of these compounds in the treatment of cancer.
These forward-looking statements are based on current information that is
likely to change and speak only as of the date hereof.

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These adjuvants have been shown
to induce tumor rejection responses in a mouse model of breast cancer , the
neu-transgenic animal. Ascentia is
developing and commercializing new pharmaceutical and biomedical products for
application in a number of areas, including treatment for asthma, arthritis ,
psoriasis and cancer. Using this enhanced
sensitivity, scientists were able to show a higher association between HPV and
many cervical, head/neck and schistosomiasis-associated bladder cancers than
previously realized, it was announced today by SEQUENOM, Inc.

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While the
happiness impact of friendship and money are gender neutral, the importance of
relationships, grades, and sex are gender dependent.org/current.S.sequenom.

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The
potential to use HPV as a marker for tracking these types of cancers has
increased as a result of the sensitivity of the MassARRAY system., Ph.

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com."

About Ascentia Biomedical Corporation
Our focus is SOLUTIONS through RESEARCH and DISCOVERY.

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The least happy? Only 55% of guys 15-17 said they were happy. Many
currently tested molecules and compounds fail to activate tumor rejection
responses despite eliciting potent immunity. For more information on the study, please visit
the publisher's website at http://www .

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35% of females say it is extremely/somewhat important to their
happiness).
Although 56% of respondents have had sexual intercourse, sexually active
young adults are no happier than their non -sexually active peers. Furthermore, other adjuvants that are known to
enhance immunity when used in parallel studies failed to control tumor growth."

These compounds will also be examined for additional indications:
* As a treatment for sepsis, a life-threatening condition caused by
infection
* As a treatment for autoimmune disorders such as arthritis
* As an adjuvant for vaccines used in the prevention of multiple
diseases.
(Logo: http://www. These
forward-looking statements are subject to risks and uncertainties that may
cause actual results to differ materially, including the risks and
uncertainties associated with the development and commercialization of any new
technology, and particularly technology related to or involving diagnostic
tests and treatment or monitoring of diseases such as cancer, and other risks
detailed from time to time in SEQUENOM's SEC filings, including SEQUENOM's
most recently filed Annual Report on Form 10-K for the year ended
December 31, 2004 and most recently filed Quarterly Report on Form 10-Q.

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"This study validates that MassARRAY
technology offers a level of sensitivity and specificity that is unmatched. Clinical studies
have confirmed that almost 15 types of HPV are a causal factor in the
development of cervical cancer, the second most common cancer in women.

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When differences are noted between
groups, these are based on statistically significant differences. The company fuses journalism with
consumer-generated content to catalyze conversations about things young people
want and need to talk about -- music, movies, gaming, dating, activism and
technology.

Ascentia Biomedical Corporation Further Defines Option Agreement With University of Washington for Anti-Cancer Compound

Another important finding was that the inclusion of Ascentia's novel adjuvants
led to a strong recall response to antigens suggesting that the 'immunologic
memory' was induced, an ideal outcome of immunization that can lead to long
lasting protection against tumor.com/cgi-bin/prnh/20040415 /SQNMLOGO)
"The MassARRAY system's ability to reliably analyze trace amounts of
genetic material and yield superior data quality already has been proven in
non-invasive prenatal testing applications ," stated Charles Cantor, Ph. Approximately 30
of the 100 identified HPV types are sexually transmitted .

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Sex
Not surprising, having sex is more important to guys than girls (55% of
males vs. Utilizing novel MassARRAY assays, HPV DNA was detected at the
single molecule level, yielding data far more sensitive than available with
current standard procedures.

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The research provides evidence that
the technique may be useful to monitor therapy as well as to accomplish early
diagnosis as the virus disappears when the dysplasia is removed. Based on
the presence or absence of HPV in serum and/or PBF, it might be possible to
monitor the occurrence and treatment of these types of cancer non-invasively.D, Chief Medical Officer of SEQUENOM. Annual
spending on diagnosis and treatment of cervical disorders is greater than $5
billion. The Company's proprietary MassARRAY system is a
high -performance DNA analysis platform that efficiently and precisely measures
the amount of genetic target material and variations therein.

SEQUENOM(R) and MassARRAY(R) are registered trademarks of SEQUENOM, Inc.

This category contains sites about using surgery or other medical treatment to assign gender to children with ambiguous genitalia.

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19% of females, a 31%
difference.
45%).
A sampling error of +/- 4% (95% confidence level) is assumed for
statistics based on the total sample size.

Dr. Clagett (CEO) and Reife (CSO) will lead the development of the
other compounds for the treatment of sepsis and autoimmune diseases and as
vaccine adjuvants.

About SEQUENOM
SEQUENOM is committed to providing the best genetic analysis products that
translate genomic science into superior solutions for molecular medicine and
biomedical research.

appendix clitoral

Factors Extremely/Somewhat Important to Gen Y Happiness


Overall Males Females

Having good friends 96 % 96 % 96 %
Getting along with parents 84 % 80 % 87 %
Getting good grades 77 % 71 % 85 %
Having a boyfriend /girlfriend 72 % 79 % 65 %
Having money 71 % 69 % 72 %
Having sex 45 % 55 % 35 %

Friendship
Universally, friends are the most important factor contributing to
happiness, with 96% of respondents saying having good friends was somewhat or
extremely important to their happiness.

Parents
Getting along with parents is the next most important factor for both
males and females (84% say somewhat/extremely important).
Dr. Now, the major goal of the
biotechnology industry is to identify the vaccine adjuvants, called 'danger
signals ,' which elicit an immune response that can destroy tumors.com

Certain statements contained herein are "forward looking" statements as
such term is defined in the Private Securities Litigation Reform Act of 1995.

MassARRAY(R) System Offers Significant Improvement in Sensitivity for Detection of Human Papillomavirus

(Nasdaq: SQNM).

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Among the more interesting findings, the study revealed that males are 13%
more likely than females to say that having a boyfriend/girlfriend is
extremely important to their happiness. 50% of
males 15-17 years old say sex is important vs. Initially, a majority of these products will be secured
through direct purchase or through licensing . Ascentia is focused on
therapies for cancer and diseases of inflammation.pnas.newscom.,
Chief Scientific Officer of SEQUENOM. Of
even greater significance, HPV DNA was detected in the blood and/or serum of
women with the common pre-cancerous condition of cervical dysplasia.

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Females value
parental bonds more than males as they get older.
Significantly, researchers found that this may lead to the ability to detect
HPV in the blood and/or serum of women with cervical dysplasia, a common
pre-cancerous condition of the cervix.D., there are
approximately 20 million people currently infected with HPV.

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com Monthly Omnibus study. Although equally important
to males and females 15 -17 years old, it increases in importance for females
18-22 and decreases in importance for males ., Ascentia Biomedical
Corporation (OTC Pink Sheets: ASCE), a leading researcher and developer of
efficacious pharmaceuticals, compounds and other products, announces
additional details on the novel compounds covered in the option agreement with
the University of Washington, Seattle, WA.
Dr.

Except for the historical information contained herein, the matters set
forth in this press release including statements regarding the potential non-
invasive early cancer detection method for cervical, head and neck and certain
bladder cancers, the ability to detect HPV in the blood and/or serum of women
with cervical dysplasia, the usefulness of the method to monitor therapy and
accomplish early diagnosis, the potential to use HPV as a marker for tracking
cancer and monitoring occurrence and treatment of cancer non-invasively, and
the potential for MassARRAY technology to complement the use of the pap smear,
are forward-looking statements within the meaning of the "safe harbor"
provisions of the Private Securities Litigation Reform Act of 1995.

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Founded in 1996, Bolt is headquartered in New York City. As an example of the adjuvant activity of these novel
compounds , animals that were immunized with tumor antigens along with the
novel adjuvants had tumors about 1/4th the size of control animals 50 days
following tumor development.
Because statements include risks and uncertainties, actual results may differ
materially from those expressed or implied and include, but are not limited
to, those discussed in filings by the Company with the Securities and Exchange
Commission. The system is
able to deliver reliable and specific data from complex biological samples and
from genetic target material that is only available in trace amounts. For more
information , please visit http://www.

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BELLEVUE, Wash. As the Company grows and
evolves, more products will be developed internally.

For more information visit the Company's website at:
http://www .

This is essential in molecular medicine where non-invasive biomarkers can be
used for the detection and treatment of cancer associated with HPV.

About HPV
Human papillomavirus (HPV) infection is a common virus known for causing
warts especially on the hands, feet and genitals .

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The
study also found young people are most happy in the "honeymoon period" of a
relationship (78%) compared to those in longer term (6+ months) relationships
(68%) and those who are not in relationships (63%). Knutson said, "It is now well accepted that immunity to tumor antigens
can be elicited with the use of vaccines. - Study Suggests Potential Non-Invasive Early Cancer Detection Method for
Cervical, Head and Neck and Certain Bladder Cancers

SAN DIEGO, As reported today in the
Proceedings of the National Academy of Science, the MassARRAY(R) technique
detecting human papillomavirus (HPV) is 1,000 fold more sensitive than the
current standard method while maintaining specificity.

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