001) (1)
-- Q-LES-Q SF mean percentage change scores at final assessment (LOCF)
were significantly greater in both SEROQUEL treatment groups (20.(3) Both men and women are equally at risk for this illness, which
most often emerges in adolescence or young adulthood and recurs throughout
life.
The FDA proposed boxed warning also notes that these drugs are not approved
for treatment of elderly patients with dementia-related psychosis. Harrison G. Gough's talk was met with resounding enthusiasm from the large
audience.
CPP, Inc. To learn more about
CPP and its assessments , visit http://www.

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Quality of life is of critical
importance for patients with bipolar disorder because they often experience
relationship and work problems," said Jean Endicott, Ph. Patients starting treatment with
atypical antipsychotics who have or are at risk for diabetes should undergo
fasting blood glucose testing at the beginning of and during treatment. Mark Snyder, Professor of Psychology at the University of Minnesota
and Chair of the SPSP Awards Committee, said, "This award was intended to look
back and celebrate a lifetime of achievement and contributions to personality
research.
The Association for Research in Personality, which was holding meetings in
New Orleans in conjunction with SPSP, presented a special symposium in honor
of Dr.

About Harrison G.org.

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Without appropriate treatment, patients usually suffer for a lifetime with
periods of wellness and functioning punctuated by severe episodes of
illness.
Dr. Its hundreds of offerings have been used by millions
worldwide for 48 years in such applications as leadership development ,
coaching, team building, retention, and career management.

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SEROQUEL is
currently under investigation for use in the treatment of bipolar depression., U."

ABOUT BIPOLAR DISORDER
Bipolar I disorder consists of recurring episodes of mania with or without
depression. Rochester, Minn. degree in 1949. In 1956 he co-
founded Consulting Psychologists Press, now CPP, Inc.

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"The depressive phase of bipolar disorder, which patients experience
approximately three times as often as the manic phase, is associated with
significant impairment in quality of life.D. Medical Director for
SEROQUEL .

ABOUT ASTRAZENECA
AstraZeneca is a major international healthcare business engaged in the
research, development, manufacture and marketing of prescription
pharmaceuticals and the supply of healthcare services.

About the Society for Personality and Social Psychology
Since its founding in 1974, the Society for Personality and Social
Psychology (SPSP) has become the world's largest organization of social and
personality psychologists.

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"
The BOLDER study , an eight-week, double-blind, placebo-controlled trial,
assessed SEROQUEL 300 mg/day and 600 mg/day versus placebo for the treatment
of depression in 542 patients with bipolar I and II disorders.
Myers-Briggs Type Indicator, Myers-Briggs, and MBTI are registered
trademarks of the Myers-Briggs Type Indicator Trust.

'Transgenderism' is an umbrella term covering persons who do not fit societal expectations of sex or gender.

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001) (1)
-- The most common adverse events in the trial included dry mouth ,
sedation or somnolence, dizziness and constipation (1)

"Improved quality of life is key in helping patients manage bipolar
disorder symptoms," said Wayne Macfadden, M. Patients should be
periodically reassessed to determine the need for continued treatment. A randomized, double -blind, placebo-controlled trial of
quetiapine in the treatment of bipolar I or II depression . Gough was honored for a lifetime of commitment and
achievement in the field. He responded, "I am
profoundly grateful for this honor, and I am humbled by the knowledge that so
many members of the Society -- colleagues and former students -- contributed
to the work that is honored. Gough is the author of a number of personality assessment instruments,
including the California Psychological Inventory(TM) (CPI(TM)), the Adjective
Check List, and the Personnel Reaction Blank."
In accepting the award, Dr.cpp.

About CPP, Inc.

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, is a leading provider of innovative assessments and training
tools administered by professionals to meet individual and organizational
development needs. In addition to the
California Psychological Inventory(TM) (CPI(TM)) 434, CPI 260(TM), and the
Adjective Check List, CPP's research-validated products include the Myers-
Briggs Type Indicator(R) (MBTI(R )), Strong Interest Inventory(R), Fundamental
Interpersonal Relations Orientation -- Behavior(TM) (FIRO-B(R)), Thomas-
Kilmann Conflict Mode Instrument (TKI), and Parker Team Player Survey
assessments .com.

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The Q-LES-Q SF is a common measurement tool used to assess quality of life in
patients experiencing depression.9 in
the 600 mg/day group and 19.
Precautions include the risk of seizures , orthostatic hypotension and
cataract development.seroquel. AstraZeneca is listed in the Dow Jones Sustainability Index
(Global) as well as the FTSE4Good Index.; from 1956-1996 he
served on the CPP, Inc.com.

For More Information Contact
John Neely
Hawthorne Associates
Phone: 978-745-4878
Fax: 978-745-2553
john@hawthorneassociates.

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(3) In the long term, patients with bipolar I disorder
experience depressive symptoms three times longer than manic symptoms. (formerly Consulting
Psychologists Press), Dr. The CPI is a measure of positive, life-enhancing
attributes of personality, such as social responsibility, tolerance, and
leadership.

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Hyperglycemia , in some cases extreme and associated with ketoacidosis,
hyperosmolar coma or death, has been reported in patients treated with
atypical antipsychotics, including SEROQUEL.6 billion healthcare business with more than 12,000
employees. Five speakers from American and British
universities participated in this symposium.

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3 in the 300 mg/day group) than in the
placebo group (11.5) (p is less than or equal to 0.
The most commonly observed adverse events associated with the use of
SEROQUEL in clinical trials were somnolence, dry mouth, dizziness,
constipation, asthenia, abdominal pain , postural hypotension, pharyngitis,
SGPT increase, dyspepsia, and weight gain.com.com

(1) Endicott J, Rajagopalan K, Macfadden W, et al. Efficacy of quetiapine
in improving quality of life in patients with bipolar depression.

, The Society for
Personality and Social Psychology (SPSP), the world's largest organization of
social and personality psychologists, has awarded Dr.
Dr. That's what we intended, but Harrison had something more in mind. Gough described four major studies in which
current information for length of life, good health, happiness, and
occupational attainment was related to CPI data gathered 40 or more years
earlier. Present were former students who, he observed, are nearing their own
retirement. Board of Directors. The goal of the society is to further the
generation and dissemination of research through scholarly journals,
conferences , and close consultation with other professional organizations.
Phone: 800-624-1765, x 179
Fax: 650-623-9271
mfox@cpp.

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, professor of
Clinical Psychology in the Department of Psychiatry at Columbia University and
Chief of the Department of Research Assessment and Training at the New York
State Psychiatric Institute. Best known of these is the CPI,
first published in 1956.

Transgendered persons include: transsexuals, cross-dressers, drag-queens, butch lesbians, intersexuals, and others .

Academic perspectives on transgenderism come from many disciplines such as psychology, history, sociology , anthropology, gender studies, queer studies, and law.

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Since its publication in 1956, two
major revisions have been published, in 1986 and 1994, and a new, modified
version for use in organizations for workforce development was published in
2002. Gough, Ph. To
find out more about the society, visit http: //www.

About the California Psychological Inventory
The California Psychological Inventory (CPI) is a measure of positive,
self-actualizing aspects of personality, which is widely used by psychologists
to help organizations find and develop successful employees, develop leaders,
create efficient organizations, and promote teamwork.com

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(1)
SEROQUEL is approved for the treatment of acute manic episodes associated
with bipolar I disorder and for the treatment of schizophrenia .

CPP's Dr. Harrison Gough Receives Award from Society for Personality and Social Psychology: Gough Recognized for Distinguished Contributions in Personality Psy

Gough The
Jack Block Award, given annually for distinguished contributions in
personality psychology. Gough in 2002. In addition, Davies-Black(R ) Publishing, CPP's book division,
offers cutting-edge business and career management titles.

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, AstraZeneca (NYSE: AZN)
today announced additional findings at the annual meeting of the American
Psychiatric Association (APA) from the BOLDER (BipOLar DEpRession) trial, a
large-scale study that examined SEROQUEL as a treatment for depressive
episodes in patients with bipolar I and II disorders. Results from this trial
showed SEROQUEL (600 mg/day and 300 mg/day) significantly improved quality of
life measures on the Quality of Life Enjoyment and Satisfaction Questionnaire
(Q-LES-Q SF).D.
For full Prescribing Information for SEROQUEL, please visit the Web site
http://www. It is one of the
world's leading pharmaceutical companies with healthcare sales of over $21.
(2) Calabrese JR, Keck PE, Macfadden W, et al, for the BOLDER Study
Group.

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Bipolar II disorder consists of recurring episodes of hypomania
and depression.
AstraZeneca received notice on April 11 , 2005, of the US Food and Drug
Administration (FDA) request that the product labeling for all atypical
antipsychotics, including SEROQUEL, be updated to include a boxed warning
noting the increased risk of mortality in elderly patients with dementia-
related psychosis taking these drugs, compared to patients taking placebo. A rare condition referred to as neuroleptic malignant
syndrome has been reported with this class of medications, including SEROQUEL. October
28, 2004 Manuscript . A comprehensive CPI bibliography containing more than 2,000 entries was
compiled by Dr. Gough's lifetime of work.

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Co-founder of CPP, Inc. The award was presented during the Society's annual
conference in New Orleans, Louisiana, January 20-22, 2005. It is used for a wide variety of assessments, including managerial
performance, honesty, and self-realization.cpp.

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Data Further Examines SEROQUEL(R) (quetiapine fumarate) Treatment for Bipolar Depression

"The results of this analysis are exciting, and reinforce the
importance of additional investigation of SEROQUEL in managing depressive
symptoms associated with bipolar disorder.
Patients who develop symptoms of hyperglycemia should also undergo fasting
blood glucose testing.4
billion and leading positions in sales of gastrointestinal, cardiovascular ,
respiratory, oncology and neuroscience products.
For more information about AstraZeneca, please visit
http://www. Mayo Clinic on Depression.: Mayo
Clinic Health Information, 2001 . In
addition to looking back, in his award address he treated us to a fascinating
glimpse at the work that still lies ahead of him.D.
He retired in 1986 as a Professor of Psychology, Emeritus.

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"
Dr. Research materials for these analyses were drawn from several
prominent projects, including the Intergenerational Study at the Institute of
Human Development, University of California, Berkeley , and the Mills College
Life-Span project. Strong Interest
Inventory, FIRO-B, and Davies-Black are registered trademarks and Fundamental
Interpersonal Relations Orientation -- Behavior, California Psychological
Inventory, CPI, and CPI 260 are trademarks of CPP, Inc.

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Data showed:
-- Significant improvement was noted at the first post-baseline Q-LES-Q
SF assessment (week 4) in both SEROQUEL groups versus placebo (p is
less than or equal to 0.S.(3)

IMPORTANT SAFETY INFORMATION
SEROQUEL is indicated for the treatment of acute manic episodes associated
with bipolar I disorder, as either monotherapy or adjunct therapy with lithium
or divalproex , and the treatment of schizophrenia.
Prescribing should be consistent with the need to minimize the risk of
tardive dyskinesia.
After four years of military service in World War II (1942 -1946), Dr.com

Mike Fox
CPP, Inc.

gender transgenderism

- Study Showed Significant Improvement in Quality of Life Measures -

WILMINGTON, Del. "These data from the BOLDER trial are important
because they recognize that quality of life is a key dimension of treatment in
bipolar disorder. Data presented
today analyzed quality of life in these patients using the Quality of Life
Enjoyment and Satisfaction Questionnaire (Q-LES-Q SF), a 16 item, self-report
survey that measures differences in the degree of enjoyment and satisfaction
among groups of patients, as well as changes over time in a single patient.spsp.

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In the United States,
AstraZeneca is a $9.astrazeneca-us.
Gough entered the graduate program in clinical psychology at the University of
Minnesota, where he received a Ph. He then accepted a
position in the Department of Psychology, University of California, Berkeley. To find out more about
the CPI 434 and the CPI 260(TM), to view sample reports, and to download a
free copy of Comprehensive Bibliography of the CPI(TM) Assessment, visit
http://www.

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(2)
Patients with bipolar II disorder have traditionally been difficult to treat
as they spend almost forty times longer in the depressed state than in mania.
Annual Meeting of the American Psychiatric Association , 2005,
Atlanta, Georgia, poster 327. MOUNTAIN VIEW, Calif.

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(3) Kramlinger K.D.

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---

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