Altman received his B. in Biology at the University of
Pennsylvania. He maintains his private practice in Brookline,
Massachusetts.

PRESS RELEASE Ushercell Enters International Phase II Trial for Bacterial Vaginosis Treatment and Prevention



Polydex has committed the necessary funding to complete this trial, and
CONRAD continues its support in the development of Ushercell by providing
the clinical trial supplies necessary to carry out this trial. Plus, headline grabbing sex
surveys and stories.

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About VIVUS
VIVUS, Inc.

The study will be carried out under the direction of Dr.

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com/webcast/vivus/ and archived for 30 days.A. He graduated with honors from the New York University School of
Medicine in 1975. A report could be available as early as late 2006.com

We're uncovering new areas while keeping the classics like erotic
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The symposium
will include Dr.

CONTACT: Christina Weisgerber of VIVUS, Inc. BV is also associated with
increased risk of HIV acquisition and transmission. The two HIV prevention trials are expected to
last approximately three years, with a further year required to evaluate
the data. And while we
still have our great looking nudes, we're featuring them in new and enticing
ways and have recruited top photographers for more women-friendly erotic
imagery.

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Susan R.

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VIVUS will provide a live webcast of the symposium, accessible at
http://www.

Please visit our website: www.polydex. Some of our new
monthly features include:

* Sexual Health, a no-nonsense monthly feature by well -known New York
City Ob/Gyn Dr.

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Dr.com.


Jose Simoes and Dr. Food and Drug
Administration or equivalent foreign regulatory authorities as well as
results of pending or future clinical trials . Carol Livotti and her daughter, Elizabeth Topp. This
writing team gives you a doctor's knowledge , plus advice even your best
friends couldn't deliver.com/cgi-bin/prnh/20030102/PLAYGIRLLOGO )

We've also added Destinations, a ticket to romantic travel and sexy
getaways, Delectables for all of you who love food and Stimuli, the "latest
and greatest" sex toys, fashion accessories , cosmetics, jewelry, lingerie,
home accents and everything else women lust for.. For further information on this
or any future issues, please contact 646/658-7581 or pr@playgirlmag.

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She now focuses her research and clinical practice on the consequences and
management of sex steroid depletion in women . For more information on clinical trials and products, please
visit the Company's web site at http: //www.

Sites which offer news or articles on various aspects of sexuality.

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" The American College of Obstetricians and Gynecologists (ACOG)
has accredited this program to receive 1 continuing medical education (CME )
credit." Her particular area of expertise is gynecological
endocrinology with an emphasis on clinical practice, research and education.





Polydex Website


"We are delighted that Ushercell continues to show a high safety profile
and broad spectrum antimicrobial activity, securing recommendations from
Dr.and getting there very fast (a lot like
PLAYGIRL Magazine!).

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Alan M. Not only is BV a common problem that requires treatment,
Bacterial Vaginosis may also act as a co-factor in the heterosexual
transmission of HIV.

CONRAD and Family Health International are conducting the Phase III HIV
Prevention trials in Africa and India, with funding from USAID and the Bill
and Melinda Gates Foundation.S.
This sexplorer gives
readers the 411 on all things lustful, lascivious, and potentially
problematic.

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Davis
trained as a Specialist Physician in Endocrinology at Prince Henry's Hospital
in Melbourne and later completed her PhD on "The molecular biology of female
ovarian inhibin.
is a pioneer in the research and development of proprietary
products to restore sexual function for women and men. By day 14 of that trial,
89% of the patients with BV that were assigned the use of Ushercell no
longer had BV. A Phase II clinical trial for fertility regulation
has recently been completed in the United States and two Phase III trials
to determine efficacy in the prevention of HIV/AIDS, gonorrhea, chlamydia
and herpes 1 and 2 are ongoing in Africa and India.

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Altman's presentation addressing transdermal estrogen and Dr.
Davis's focusing on transdermal testosterone. Altman, MD is Assistant Clinical Professor of Obstetrics,
Gynecology and Reproductive Biology at Harvard Medical School. Other risk factors discussed
in the Company's filings with the United States Securities and Exchange
Commission may also affect the actual results achieved by the Company..

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VIVUS Announces Symposium /Web cast at the 53rd American College of Obstetricians and Gynecologists Annual Meeting

Alan M.

(Nasdaq: VVUS), a specialty pharmaceutical company focused on the research,
development and commercialization of products to restore sexual function in
women and men, today announced it will host a breakfast symposium on Monday,
May 9, 2005 at 6:00 a. on the "Transdermal Delivery of Hormones: The
Benefits of Non-Oral Estrogen Delivery and The Role of Testosterone Therapy
for Women. Dr. All participants will be
counseled to use an effective non-barrier method of contraception
throughout the trial . Actual events or results may differ
materially from the Company's expectations, which are subject to a number
of known and unknown risks and uncertainties including but not limited to
changing market conditions, future actions by the U.

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m.
She has published over 150 peer-reviewed manuscripts and has written two
books for women, The Healthy Woman and Our Health, Our Lives. VIVUS' current product
pipeline includes four investigational products in late stage clinical
development.

BV is defined as a clinical syndrome in which the normal
lactobacilli-predominant vaginal flora is replaced by an overgrowth of
Gardnerella vaginalis and anaerobic microorganisms. A BV treatment may represent our
fastest route to the market for Ushercell," he continued.

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He
is well known for his ability to sift through even the most complex problems
in these areas and help guide women to the best kind of treatment if treatment
is necessary.newscom." We choose
this "Party For Two" singer not only because he's gorgeous, but also because
it's clear he's going places.
PLAYGIRLS know that change is good and we're proud to show off our new
look that is as contemporary as our readers.

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Davis, MBBS, FRACP, PhD, is the Professor of Women's Health,
Monash University, and Director of the Monash University NHMRC Centre of
Clinical Research Excellence in Women's Health, Victoria , Australia.

Note: This press release may contain forward-looking statements, within the
meaning of the United States Securities Act of 1933, as amended, and the
United States Securities Exchange Act of 1934, as amended, regarding
Polydex Pharmaceuticals Limited.

PLAYGIRL Features New Look and Content in Magazine Makeover

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He later completed his internship and residency at the
Boston Lying -In and Free Hospital for Women, which then became the Brigham and
Women's Hospital.vivus.

It is estimated that this randomized, blinded Phase II clinical study will
last approximately six months , after which the data will be unblinded and
analyzed. The protocol
for this study has been designed to conform to FDA guidelines.

* Sex.com
The March issue of PLAYGIRL hits newsstands nationwide on February 11,
2005.

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Polydex Pharmaceuticals Limited (NASDAQ: POLXF) is
pleased to announce the commencement of a randomized, blinded Phase II
clinical trial of Cellulose Sulphate (Ushercell), a microbicidal gel which
is being tested for its effectiveness in the treatment of Bacterial
Vaginosis (BV), the most common vaginal disorder among reproductive-age
women, present in 15-25 % of gynecologic patients and up to 60% of women
seen at sexually transmitted diseases clinics. Lourens Zaneveld to assess its potential as a
treatment for BV," said George Usher, President and CEO of Polydex.

CONRAD, located in Arlington, VA, has played an instrumental role in
developing cellulose sulphate with the support of USAID and private
foundations, and in clinical collaboration with Family Health
International, WHO and NIH.

Polydex Pharmaceuticals Limited, based in Toronto, Ontario , Canada, is
engaged in the research, development, manufacture and marketing of
biotechnology-based products for the human pharmaceutical market, and also
manufactures bulk pharmaceutical intermediates for the worldwide veterinary
pharmaceutical industry.

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Altman, Harvard Medical
School and Dr. Davis, Monash University, Australia on the
Transdermal Delivery of Hormones

MOUNTAIN VIEW, Calif., VIVUS, Inc., +1-650-934-5240.

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Susan R. Dr.

Ushercell is a high molecular weight cellulose sulphate polymer derived
from natural cotton, and has successfully completed numerous Phase I safety
and tolerability trials.

(Logo: http://www.

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Symposium Will Feature Presentations by Dr. Therefore, the impact of Ushercell as a BV treatment
warrants further study. Columnist Billy Sprang polls the boys at the bar
to get their uniquely male point-of -view. You won't find the same orgasm article month after month
in PLAYGIRL -- we know more!
You'll notice gracing the cover of our first issue is country music star
Billy Currington, one of Nashville's "25 Most Beautiful People.

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In an earlier published
study, Ushercell demonstrated a growth-inhibition effect on BV-associated
bacteria in vitro, and the study report concluded with recommendations to
further study the effects of Ushercell as a treatment for BV. "The
second study with equally encouraging indications of BV clearance confirms
the potential we envision for Ushercell . Jose Simoes, at
the University of Campinas, Sao Paulo, Brazil, and will involve 60 women
having a clinical diagnosis of BV, and no other sexually transmitted
diseases or reproductive tract infections .

* Friends with Benefits gives Playgirls the opportunity to hear a guy's
take on sex and women.

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Davis is
President of the Australasian Menopause Society. NEW YORK, For more than 30 years, PLAYGIRL has
been the place for women to explore their sexuality and like our readers , we
only get better with age (but a little makeover does wonders!).

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He is a
practicing gynecologist who specializes in peri and post-menopausal care,
problems with hormone replacement therapy and issues of mid-life sexuality.Ed finds PLAYGIRL sexpert Jayme Waxman sharing her wit and wisdom
on the trials and tribulations of relationships.

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In a subsequently published report delivered at the 12th Conference on
Retroviruses and Opportunistic Infections in Boston, the results of a
clinical trial conducted by the HIV Prevention Trials Network (HPTN049)
wherein 59 HIV+ women enrolled to assess Changes in Vaginal Flora
Associated with Vaginal Microbicides, 43% of these participants had
Bacterial Vaginosis at the time of enrollment. CONRAD, which was established and funded by
USAID at the Eastern Virginia Medical School, has focused on developing
safe, effective, acceptable and affordable methods of contraception and
microbicides for the prevention HIV/AIDS and other sexually transmitted
infections.

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