Leading Expert on Gene Signaling

BOULDER, Colo.
As stated by Howard Robin, President and Chief Executive Officer, "Dr. Dr. Sirna has strategic partnerships with Eli Lilly
and Company, Targeted Genetics and Archemix Corporation and a leading
intellectual property portfolio in RNAi. More information on Sirna
Therapeutics is available on the Company's web site at http://www.

Contact information:
Elizabeth Gravatte
Director of Marketing
VivoMetrics Inc.

mahesh tm

ARAMARK received the award in the Very Large Corporation category ,
which evaluates for-profit companies with 1,000 or more employees.
Dr."
From 1996 -2000, Dr.

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ARAMARK was ranked number one in its industry in the 2005
FORTUNE 500 survey and was also named one of "America's Most Admired
Companies" by FORTUNE magazine in 2005, consistently ranking since
1998 as one of the top three most admired companies in its industry as
evaluated by peers . Both Sirna
management and the members of the Board of Directors look forward to his
participation in our scientific meetings and decisions. I am impressed with Sirna's capabilities and
believe that Sirna is leading the way in the development of siRNA
therapeutics.sirna. When participants started running on a
virtual track and reached a 60-70% maximum heart rate on the third lap, a
virtual competitor appeared on the track stimulating a self reported
frustration as the athlete was required not to increase work load, rather let
the competitor stay ahead of them on the track.

For more information about the LifeShirt System, visit
http://www.

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Headquartered in Philadelphia , ARAMARK has
approximately 242,500 employees serving clients in 19 countries. His research focuses on the mechanisms
of signaling and gene regulation by intracellular receptors that mediate the
actions of several classes of essential hormones. Yamamoto was a founder of the journal Molecular Biology of the Cell
and served as Associate Editor, Editor or Editor-in-Chief from 1989-2003.,
+1-303-449 -6500 or Jason Rando, The Ruth Group, +1-646-536-7025

"With the
LifeShirt, for the first time, we can monitor how positive or negative stimuli
affect the athlete as he performs.

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"We thank the Pennsylvania Psychological
Association for this distinction, and we will continue to focus on
delivering a healthy work environment for all of our employees.D. The LifeShirt was then used to
record variations in heart rate and respiration, known as additional heart
rate, to determine how competitors may affect the physiological responding of
an athlete who self reports frustration during competition. The
LifeShirt System has received FDA clearance and EMEA approval (CE Mark).

798.

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Sirna has initiated a Phase 1
clinical trial for its most advanced compound, Sirna-027, a chemically
modified siRNA targeting the clinically validated vascular endothelial growth
factor pathway to treat AMD. Finn PhD, a key researcher in
the study and professor of Psychology at Saint Anselm College .

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to its Scientific Advisory Board as Chairperson."
About his appointment Dr.com

About the LifeShirt System
The LifeShirt System is the first non-invasive, ambulatory monitoring
system that continuously collects, records and analyzes a broad range of
cardiopulmonary parameters. Data collected by integrated peripheral devices measure blood
pressure, blood oxygen saturation, EEG/EOG , periodic leg movement,
temperature, end tidal CO2 and cough.

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He will provide insightful guidance
to both internal research as well as assisting with relationship building that
can potentially support our external collaboration efforts. The
LifeShirt, a non-invasive, light weight garment used to monitor respiratory
and cardiopulmonary function, will enable researchers to help establish how
mood affects athletic performance. Pharmaceutical companies use VivoMetrics' technologies to
improve the speed and economics of clinical research.

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"
ARAMARK will receive the award on June 16, 2005 at the 2005 Annual
Convention of the Pennsylvania Psychological Association in
Harrisburg, Pa.

Sirna Therapeutics Appoints Dr. Keith Yamamoto to Chairperson of SAB

and SAN FRANCISCO, Sirna
Therapeutics (Nasdaq: RNAI) announced today the appointment of Keith Yamamoto,
Ph. Government agencies to protect the lives of military and
civilian first responders.

The scientific research on the Transcendental Meditation and TM-Sidhi program of Maharishi Mahesh Yogi is the largest and strongest body of research in the world on any program to develop human potential.

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Risks and uncertainties include Sirna's early stage
of development and short operating history, whether Sirna can achieve and
maintain profitability , whether Sirna can obtain and protect patents, the risk
of third-party patent infringement claims , whether Sirna can engage
collaborators and obtain regulatory approval for products, Sirna's
concentration of stock ownership, and availability of materials for product
manufacturing."
The study began in the fall 2004 and will conclude in spring 2005.

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Contacts:
Martin E.
A total of 23 participants, including 17 college varsity athletes wore the
LifeShirt in a virtual reality scenario.vivometrics.275.

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Business Editors/Food/Beverage Editors

PHILADELPHIA----ARAMARK Corporation
(NYSE:RMK), a world leader in managed services, has won the
Psychologically Healthy Workplace Award, sponsored by the Pennsylvania
Psychological Association and the American Psychological Association.
"Creating a strong, productive work environment means offering
employees a fair, safe and balanced workplace that helps them achieve
to the best of their abilities," says Ross DeSimone , a partner at
Delta Consultants and chair of the Pennsylvania Psychological
Association's Business and Psychology Partnership Committee."

About ARAMARK

ARAMARK Corporation is a world leader in providing award-winning
food and facilities management services to health care institutions,
universities and school districts, stadiums and arenas, international
and domestic corporations, as well as providing uniform and career
apparel.
Dr.com/. Vice President + CFO of Sirna Therapeutics, Inc.S.5834
egravatte@vivometrics.

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Yamamoto's research has had a major impact on the fields of molecular
biology, endocrinology and physiology.

About Sirna Therapeutics
Sirna Therapeutics is a clinical-stage biotechnology company developing
RNAi-based therapies for serious diseases and conditions, including
age-related macular degeneration (AMD), Huntington's disease, diabetes,
asthma , oncology, hepatitis C and hair removal. These and additional risk factors are identified in Sirna 's
Securities and Exchange Commission filings, including the Forms 10-K and 10-Q
and in other SEC filings. VENTURA, Calif.

neurophysiological researches

Dr. The virtual environment included a
headset which projected a visual representation of a running track while the
athlete ran on an elliptical machine.

About VivoMetrics
VivoMetrics, founded in 1999, provides ambulatory monitoring products and
services for the collection, analysis and reporting of subject-specific
physiologic data.

physiological strongest

Yamamoto served as Chairperson of the Advisory
Committee to the Center for Scientific Review, the body at the National
Institutes of Health (NIH) that determines how the majority of federal
biomedical research funds are distributed., The assessment of physiological
mood shifts among athletes during a competitive virtual reality environment
will be tracked and evaluated by researchers at Saint Anselm College in
Manchester, New Hampshire, using the LifeShirt System from VivoMetrics(R).

sociological sphere

The Psychologically Healthy Workplace Award honors organizations
that demonstrate a commitment to employees' psychological health and
well-being. He
has served on numerous national policy committees including the National
Academy of Sciences Panel on Scientific Responsibility and the Conduct of
Research (1990-1991 ), the Public Policy Committee of the ASCB (1992-2001), the
NIH Director's Peer Review Oversight Group , (1996-1999) and the Lasker
Foundation Forum on Ethical Challenges in Biomedical Research and Practice
(2003). Dr. Schmieg, Sr.com

supplementing neurophysiological

Yamamoto has been a member of the UCSF faculty for more than 25 years
starting as an Assistant Professor in the Department of Biochemistry and
Biophysics in 1976. Yamamoto is one of the most prominent workers in
the field of gene expression regulation . Users wear a lightweight, machine washable garment
with embedded sensors that collect pulmonary , cardiac, posture and activity
signals.

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He served as
the Director of the Biochemistry and Molecular Biology Graduate Program at
UCSF from 1988 to 2001 and as Chairperson of the Department of Cellular and
Molecular Pharmacology from 1994 to 2003. Yamamoto said, "I am pleased to join the SAB of
Sirna as its Chairperson.1420
gita@connors.

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ARAMARK Named One of Pennsylvania's Healthiest Places to Work by Pennsylvania Psychological Association; Psychologically Healthy Workplace Award Recognizes ARA

Dr. Yamamoto
played a key role in reforming the grant peer review process at the NIH.
Yamamoto was elected as a member of the American Academy of Arts and Sciences
in 1988, the National Academy of Sciences in 1989, as a fellow of the American
Association for the Advancement of Sciences in 2002 and to the Institute of
Medicine in 2003. Sirna undertakes no obligation to revise or update
any forward-looking statements in order to reflect events or circumstances
that may arise after the date of this release. Key
findings and final results will be available in May 2005.

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Yamamoto currently serves on the Joint Steering Committee for
Public Policy and the National Academy of Sciences, Board on Life Sciences.

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He and his colleagues have
described their research in over 150 published studies .
805.com

Gita Chandra
Connors Communications
for VivoMetrics
212.

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"With more than 242,500 employees globally, it is essential to the
growth of our business to make our company a place where the best
people want to work," says Lynn McKee, executive vice president,
ARAMARK Human Resources.

eeg sphere

Companies are evaluated in several areas, including
employee involvement in the organization's mission and vision,
work/life balance, employee growth and development opportunities, and
workplace health and safety.
Yamamoto's decision to join Sirna's Scientific Advisory Board and to take on
the position of Chairperson is a major development in Sirna's leadership in
the development of RNAi.

Statements in this press release which are not strictly historical are
"forward-looking" statements which should be considered as subject to many
risks and uncertainties .
"Previously clinical researchers used physiological monitoring equipment
to monitor mood assessment and performance but the equipment limited
participants to a sedentary position," said Dr. An electronic diary captures subjective
user input and all physiologic and subject data are correlated over time. The company's offerings
also enable academic researchers to discover new clinical signatures of
disease, and U.

sociological transdisciplinary

"ARAMARK
demonstrated that its commitment to providing its employees with a
great place to work was head and shoulders above the rest. Dr. In this position, Dr. He
serves on numerous other editorial boards and scientific advisory boards.

The more than 500 scientific studies conducted at 200 independent universities and institutions in 33 countries and published in over 100 leading scientific journals have documented that this technology benefits every sphere of life: physiological, psychological, sociological, and ecological.

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Yamamoto is
currently Executive Vice Dean at the UCSF School of Medicine.

LifeShirt(R) System to Be Used in New Research Study to Assess How Moods Affect Athletic Performance

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