,
professor of Psychiatry and Pharmacology, Department of Psychiatry, University
of Texas Health Science Center at San Antonio. "In addition
to our focus on bipolar disorder, Abbott scientists are investigating new
therapeutic approaches to depression, schizophrenia and cognitive disorders,
such as attention -deficit hyperactivity disorder and Alzheimer's disease. Depakote ER is also approved as monotherapy and adjunctive therapy in
the treatment of adults and children 10 years of age or older with complex
partial seizures that occur either in isolation or in association with other
types of seizures .
Abbott's news releases and other information are available on the
company's Web site at http: //www.

existential transcendence

----ValueOptions
announced today that they will license Beating the Blues(R),
proprietary technology from Ultrasis that enables patients to monitor
and direct their own mental health progress through cognitive behavior
therapy.. British Journal of
Psychiatry, 2004 (185) and Psychological Medicine, 2003 (33)).

naturalistic existential

The company has a
commitment to the development of quality products and Beating the
Blues(R) has been shown to be clinically effective in trials which
have been published in major medical journals (e. - Extended-Release Formulation Offers Patients Conveniences of
Once-Daily Therapy -

ABBOTT PARK, Ill. Bipolar disorder is a brain disorder that
causes unusual shifts in a person's mood, energy and ability to function. 5
percent ) and abdominal pain (10 percent vs. Depakote ER is also indicated for use as sole and
adjunctive therapy in the treatment of simple and complex absence seizures in
adults and children 10 years of age or older, and adjunctively in adults and
children 10 years of age or older with multiple seizure types that include
absence seizures. In a clinical
trial of valproate in elderly patients with dementia, some patients taking
valproate experienced somnolence, sometimes requiring discontinuation . Both facilities are located in Ontario.

"This agreement allows us to effectively achieve a significant
increase in UF6 production capacity, sales and market share by
investing a small amount of capital ," said Jerry Grandey, Cameco's
president and CEO.

Additional information on this agreement is available in a
backgrounder that is posted on Cameco's Web site at www.

capacities supremely

The
symptoms of bipolar disorder can be severe. 5 percent). Cameco disclaims any intention or obligation to update
or revise any forward-looking statement, whether as a result of new
information, future events or otherwise .

fright assumed


"Getting patients involved and actively participating in their
treatment allows them to feel like they have control over what is
going on in their lives," said Chuck Taylor, executive vice president
of ValueOptions' Employer Solutions Division."

About Ultrasis

Ultrasis is the foremost provider of a new generation of
clinically valid, computerized, interactive solutions which help
people manage stress, anxiety and depression. Like other serious
illnesses, bipolar disorder can have a negative impact on spouses, family
members, friends and the workplace. "At the same time , it preserves Springfields'
production capacity at a critical time in the industry and enables us
to lower our unit costs by utilizing Blind River's unused capacity.

westerners naikan

"
Graham Lewis, chief executive officer of Ultrasis stated that,
"This represents one more step in a progressive strategic relationship
with ValueOptions that will provide proven technology and self help
support that the members are looking for.
"Patients really enjoyed working with the program," said Stephanie
Peterson, clinical manager of ValueOptions' Louisville Staff Model EAP
office.com

About ValueOptions

One of the nation's premier behavioral health care management
organizations, ValueOptions serves nearly 23 million people across the
country through publicly funded and commercial contracts with employee
assistance, mental health and substance abuse, behavioral disability
management and integrated programs.3 million American adults have bipolar disorder, also
known as manic-depressive illness .5 vs.D.

About Abbott
Abbott is a global, broad-based health care company devoted to the
discovery, development, manufacture and marketing of pharmaceuticals and
medical products , including nutritionals, devices and diagnostics. Cameco currently has more than a quarter of the western
world's UF6 conversion capacity from its Port Hope plant.

capacities abhidharma

ultrasis.

In 2001, BNFL announced that the Springfields facility would
close in 2006.
Cameco will then deliver the UF6 to its utility customers who
ultimately use it for fuel in nuclear reactors after further
processing.

mindfulness schemas


Beating the Blues is an innovative multimedia software package
that provides a clinically proven, practice -based, self-help treatment
program for patients suffering from anxiety and depression. Designed
for use by patients with even limited computer skills, Beating the
Blues guides users through cognitive behavior modules that feature
video case studies, animation, voice-over guides and interactive
components .valueoptions. "Depakote ER produces
consistent concentrations of medication throughout a 24-hour period. Mixed mania is a state
of mind characterized by symptoms of both mania and depression. The
primary efficacy measurement was the Mania Rating Scale (MRS) total score
evaluated on Day 21 as mean change from baseline to final evaluation (Day 21). 11 percent), vomiting (13 percent vs.

Valproate may produce teratogenic effects in the offspring of women
receiving the drug during pregnancy. UO3 shipments from Blind River are expected to begin later
this year with UF6 conversion shipments from BNFL starting in
mid-2006.

"Today Cameco has taken another step toward its vision to be a
dominant nuclear energy company producing uranium fuel and generating
clean electricity ," Grandey said.

broader fright

ValueOptions Enhances Member Self-Sufficiency with Ultrasis Technology; Application Enables Patients to Direct Own Mental Health Progress

Food and Drug Administration (FDA) has approved a new
indication for Depakote(R) ER (divalproex sodium extended-release tablets) for
the treatment of acute manic or mixed episodes associated with bipolar
disorder, with or without psychotic features . Depakote ER now provides a useful
treatment option for the acute manic and mixed episodes of bipolar disorder.

Depakote ER in Acute Mania Associated with Bipolar Disorder
The effectiveness of Depakote ER was confirmed in a randomized, double-
blind, placebo-controlled parallel group, three -week, multi-center study.


"

Historically, the Blind River refinery has not operated anywhere
near full capacity since it has been limited by the capacity of
Cameco's conversion facility at Port Hope which receives essentially
all of Blind River's UO3 production. In April 2005, ownership of the Springfields plant is
scheduled to be transferred to Britain's Nuclear Decommissioning
Authority (NDA), a government agency established to take
responsibility for the majority of the United Kingdom 's civil nuclear
assets and liabilities.

psychotherapy capacities

ValueOptions and Ultrasis are discussing plans for a
web -based Beating the Blues that would provide much greater access to
this innovative program. Beating the Blues allowed them to
practice what they had learned in their face-to-face counseling
sessions , and patients left our office with a printout of their
progress charts as well as exercises to complete after their
appointment as 'homework'. Compared with Depakote(R) (divalproex sodium delayed-release tablets),
Depakote ER taken once a day helps provide more consistent levels of
medication in the body.
The frequency of adverse effects, particularly elevated liver enzymes and
thrombocytopenia , may be dose-related.abbott.

Cameco Signs Agreement Adding Uranium Conversion Capacity

Under the 10-year agreement, BNFL
will annually convert a base quantity of 5 million kilograms of
uranium (kgU) as UO3 to UF6 for Cameco.

mindfulness assumed


Ultrasis' range of products also target workplace issues such as
reduction of sickness absence and employee well-being. Hepatic failure resulting in
fatalities has occurred in patients receiving valproic acid and its
derivatives, usually during the first six months of treatment.
For full prescribing information on Depakote(R) and Depakote(R) ER please
call 1-800-633-9110.

naturalistic purify

"
ValueOptions conducted a pilot of the program in their Louisville,
Kentucky staff offices last year, and plans to roll-out the program to
additional Employee Assistance Program (EAP) offices in 2005..S. -9.

replaces naturalistic


"This expansion of the use of Depakote ER is another important step in
Abbott's commitment to developing innovative, effective and simpler treatments
for neurological and psychological disorders," said Eugene Sun, M. Valproate
is contraindicated in patients with known urea cycle disorders (UCD), a group
of uncommon genetic abnormalities, due to reports of sometimes -fatal cases of
hyperammonemic encephalopathy. Cameco expects this agreement will be accretive to
operating cash flow and earnings beginning in 2006.

BNFL is an international nuclear energy company based in the
United Kingdom.

abhidharma replaces

D., vice
president, Global Pharmaceutical Clinical Development at Abbott. Additionally, Depakote ER is approved for migraine
prevention in adults.com.

Cameco , with its head office in Saskatoon, Saskatchewan, is the
world's largest uranium producer. Cameco 's shares trade on the Toronto and New York stock
exchanges.

Although Cameco believes that the assumptions inherent in the
forward-looking statements are reasonable, undue reliance should not
be placed on these statements, which only apply as of the date of
this report.com

Cameco Corporation (TSX:CCO) (NYSE:CCJ)


naikan pitaka


"Successful treatment for mania depends upon maintaining steady levels of
medication in the blood throughout the day," said Charles Bowden, M. The
company employs 60,000 people and markets its products in more than 130
countries.

westerners sati



Business Editors /Health/Medical Writers

NORFOLK, Va. For more information, please visit
www., Abbott (NYSE: ABT)
announced that the U.
Depakote ER offers patients the convenience of taking this medication once
a day.0 with placebo).

confined morality


Common adverse events (greater than 5 percent incidence) associated with
Depakote ER or Depakote in clinical studies of acute mania patients were
somnolence, dyspepsia , nausea, vomiting, diarrhea, dizziness, pain, abdominal
pain, accidental injury, asthenia and pharyngitis . Under the agreement
with BNFL, Cameco will also ship UO3 from its Blind River refinery to
BNFL 's conversion plant where it will be toll converted to UF6.

Statements contained in this news release which are not
historical facts are forward-looking statements that involve risks,
uncertainties and other factors that could cause actual results to
differ materially from those expressed or implied by such
forward-looking statements. Factors that could cause such
differences, without limiting the generality of the following,
include: volatility and sensitivity to market prices for uranium ,
electricity in Ontario and gold; the impact of the sales volume of
uranium, conversion services , electricity generated and gold;
competition; the impact of change in foreign currency exchange rates
and interest rates; imprecision in reserve estimates; environmental
and safety risks including increased regulatory burdens; unexpected
geological or hydrological conditions; political risks arising from
operating in certain developing countries; a possible deterioration
in political support for nuclear energy; changes in government
regulations and policies, including trade laws and policies; demand
for nuclear power; replacement of production and failure to obtain
necessary permits and approvals from government authorities;
legislative and regulatory initiatives regarding deregulation ,
regulation or restructuring of the electric utility industry in
Ontario; Ontario electricity rate regulations; weather and other
natural phenomena; ability to maintain and further improve positive
labour relations; operating performance of the facilities; success of
planned development projects; and other development and operating
risks.

pitaka naturalistic

g. The company is headquartered in
Norfolk, Virginia .

mindfulness transcendence

Beating the Blues can be used in conjunction with, or as
an adjunct to, counseling or traditional psychotherapy. The patient then works on specific
problems and sets achievable goals to overcome their anxiety and
depression - thus training them in the skills they need to overcome
these obstacles in the future.

Abbott's Depakote(R) ER (Divalproex Sodium Extended-Release Tablets) Approved for Acute Manic or Mixed Episodes Associated With Bipolar Disorder

Symptoms of acute mania may
include , among others, abnormally elevated mood, irritability, marked increase
in energy, grandiose thinking and thought disorders. Patients may
feel agitated, angry, irritable and depressed all at once. Benefits of Depakote should be weighed
against risk of injury to the fetus in women of childbearing potential.cameco.

broader westerners

"Beating the Blues helps
patients identify and challenge thinking patterns and behaviors that
can be harmful to their health.
ValueOptions plans to integrate this technology as a clinical tool in
their staff-model EAP offices, allowing patients to become more active
and involved in working with their provider to guide their own
treatment. "It gave them an easy way to focus on and learn the tools of
cognitive behavior therapy. The
approval of Depakote ER for the treatment of acute mania associated with
bipolar disorder was based in part on studies establishing the effectiveness
of Depakote.

morality morita

Depakote
has been trusted by psychiatrists for a decade, and this once-a-day
formulation is important for patients.
In Depakote ER acute mania trials, adverse events with a frequency of
greater than 5 percent and at least twice as frequent as those seen with
placebo were dyspepsia (23 percent vs. Multi-organ hypersensitivity reactions
have been reported after the initiation of valproate therapy.

Cameco will invest about $6 million to expand production and
drum-filling facilities at its Blind River refinery and $4 million to
construct drum tipping and washing facilities at BNFL's Springfields
plant.

Cameco has already secured long-term commitments for a
significant volume of contracts for conversion services with utility
customers to baseload this new agreement. The company's uranium products are
used to generate electricity in nuclear energy plants around the
world, providing one of the cleanest sources of energy available
today.

morita confined

This product has been a
proven success and represents an innovative step for managed care in
the United States. Concomitant administration of valproic acid
and topiramate has been associated with hyperammonemia with and without
encephalopathy.

Cameco currently refines uranium concentrates to UO3 at the Blind
River refinery and ships this material to the Port Hope conversion
facility .

replaces mindfulness

com


"
Approximately 2."

About Depakote(R) ER
Depakote(R) ER is the once-daily formulation of Depakote(R) (divalproex
sodium delayed-release tablets), which has been a leading medication for the
treatment of mania associated with bipolar disorder since its approval in
1995.

capacities transcendence



News Editors

SASKATOON, Saskatchewan----Cameco
Corporation (TSX:CCO) (NYSE:CCJ ) announced today that it has signed a
toll-conversion agreement with British Nuclear Fuels plc (BNFL ) to
acquire uranium conversion services (UF6) from BNFL's Springfields
plant in Lancashire, United Kingdom.

sati confined

For more
information please visit www.
Depakote ER was significantly more effective than placebo in the reduction of
the MRS total score (mean change of -11.

Important Product Safety Information for Depakote ER in Acute Mania
Valproate products should not be administered to patients with hepatic
disease or significant hepatic dysfunction.
Cases of life-threatening pancreatitis, some rapidly progressing to death,
have been reported in both adults and children receiving valproate. This new agreement will keep the plant operating for
the duration of the agreement.

abhidharma substantiated

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