Based on extensive research and feedback from partners,
customers and industry experts, Microsoft's Peak Performance Initiative
provides an innovative and cost-effective approach that allows automotive
customers to take full advantage of their legacy investments while connecting
key systems, people and organizations across the automotive supply chain to
remove the barriers that stifle innovation and competitiveness.

SmartOps Multistage Inventory Planning + Optimization Software Application Licensed by HP in Latin America

universiteit proving

As a result, companies in the automotive industry
create more successful products using lower-cost parts and more efficient
manufacturing techniques . Founded as Stanford Research Institute in 1946, SRI has
been meeting the strategic needs of clients for almost 60 years. PITTSBURGH, SmartOps Corporation, a leading
provider of enterprise-class supply chain optimization software solutions,
today announced that its SmartOps Multistage Inventory Planning + Optimization
(MIPO(TM)) software solution has been licensed by HP for use by its Imaging
and Personal Systems Group in Latin America.

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com) is one of the
world's leading independent research and technology development
organizations.

ramezay engelbart

OneSpace.

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Our mechanical CAD product, Designer Modeling, is for designers who need
freedom to create and change 3D designs without misunderstandings or delay.
In the second phase of the project, SRI will increase the utility
and predictive capabilities of Pathway Logic by enhancing the ability
of researchers to interact with the models. In addition to conducting contract R+D, SRI
licenses its technologies, forms strategic partnerships and creates
spin-off companies.

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com/), to model
biological entities and processes."

About SRI International

Silicon Valley-based SRI International (www. For additional
information, contact SmartOps at 412-231-0115 or http://www.

indexing implemention

OneSpace., a leading provider of flexible CAD and collaborative
PLM software applications, today announced its support of Microsoft's Peak
Performance Initiative at the 2005 Global Automotive Summit. With
this kind of collaborative design, the knowledge and opinions of customers,
suppliers and manufacturing partners can all be integrated into product
designs and components.net combines design engineering expertise with Microsoft
technologies for a cost-effective and easily deployed solution-perfect for
companies that work with disparate CAD software, data management systems, and
partners."
The Microsoft Peak Performance Initiative is designed to help the
automotive community accelerate insight through advanced analysis services,
drive innovation by allowing teams to better collaborate, and impact
performance via increased visibility into operations across the manufacturing
value chain.

SRI International Begins Second Phase of National Institute of General Medical Sciences Grant for Mathematical Modeling of Biological Systems; Formal Method To

2's optimized inventory targets serve as critical inputs into
Enterprise Resource Planning and Advanced Planning + Scheduling systems so
they function efficiently, delivering better intelligence for inventory
planning and execution.
SmartOps' offerings have resulted in operating revenue growth and significant
supply chain savings at Fortune 500 and Global 500 companies in the heavy
automotive, consumer durables and packaged goods, technology, pharmaceutical
manufacturing, distribution, and retail industries .

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"Collaboration across the automotive manufacturing value chain is driving
innovation further , lowering costs, and ultimately providing consumers with
better products," said Kyle Solomon, automotive industry manager for Microsoft
Corp.
Model Manager, a data management product, is for teams who can't afford to
work on the wrong revision of a 3D CAD model or 2D drawing when creating
assemblies .
"Pathway Logic models of biological systems are unique in that
they are executable -- the models exist only when assembled on demand
from user-defined starting states," said Keith Laderoute, director of
SRI's Cancer Biology Program. The support of NIGMS is helping to make this possible. Sridhar Tayur , CEO and founder of
SmartOps.

indexing vrije

"This growing
responsibility brings a new level of complexity to coordinating projects. OneSpace. Promoting the mathematical modeling of
biological systems is a primary goal of NIGMS, which intends to
disseminate such tools to biologists to help them understand the new
paradigm of systems biology and to design experiments. MIPO dynamically aims to
generate optimal inventory targets for each stage of the supply chain, while
providing visibility into each reason inventory is needed -- including safety,
cycle, pre-build, pipeline and merchandising stock requirements, by item or
stock-keeping unit (SKU) -- to meet desired service levels.

calculi proving

OneSpace . SRI developed some of these tools
as part of a Web-based Pathway Logic viewer that allows multiple
queries of graphical models of EGFR biochemistry. This phase will include
development of the Pathway Logic Assistant, an application of the
InterOperability Platform (IOP), a separately funded research project
to enable the formal methods tools written in the Maude language to
communicate and interact with each other. The
nonprofit research institute performs client-sponsored research and
development for government agencies, commercial businesses and
nonprofit foundations.

engelbart indexing

cocreate. KG. Longer term ,
these tools may prove useful in validating novel therapeutic targets
and predicting the side effects of experimental therapies.csl.sri.

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net and its mission of erasing
artificial boundaries that hinder the product development cycle.
CoCreate can be found in more than 30 countries and on the Web at
http://www.

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CoCreate is a trademark of CoCreate Software GmbH + Co.----SRI
International, an independent, nonprofit research and development
institute, today announced continuation of an important grant from the
National Institute of General Medical Sciences (NIGMS, a unit of the
National Institutes of Health) to model complex mammalian signaling
networks based on signaling of the epidermal growth factor receptor
(EGFR). "This feature is one means by which
Pathway Logic offers the potential for researchers to model complex
cellular networks in a familiar or intuitive way.

About SmartOps:
SmartOps is the market leader in enterprise-class supply chain
optimization solutions that feature end-to-end capabilities designed to enable
both rapid return on investment and long term, sustainable value across the
supply chain.

conceptual vrije

Other product or service names mentioned herein are the trademarks of
their respective owners. With IOP as the
infrastructure, SRI researchers will begin to integrate a user
interface, a model repository , new visualization tools, and various
biological databases into Pathway Logic.
MIPO 3.

pioneers vrije

The Peak
Performance Initiative identifies four core areas that Microsoft and its
partners will focus on as they drive insight and innovation throughout the
automotive community.net software is built especially to support product
developers who work across multiple sites and with multiple partners . This could
dramatically speed drug development and improve the safety of new
drugs -- major issues for pharmaceutical and biotechnology companies
today.

ramezay belief

Our software provides the competitive advantage manufacturers need
to quickly adapt to new opportunities and gain sustainable top line growth.

proving reasoning

net offers the automotive
community a collaborative PLM application for working effectively across the
supply chain -- helping companies overcome the challenges of distributed
design while increasing the performance of new product development. The approach uses SRI's
patent-pending Pathway Logic (TM) pathway analysis software, based on
the Maude computer language (http://maude.sri."
MIPO is designed to enable customers to achieve both a rapid return on
investment and a long-term competitive advantage by determining the best
possible inventory and product availability plans given inherent
uncertainties, time-varying data, multi-location and inventory stage
complexities, and aggressive customer service goals.

revision proving

Gascoigne, CoCreate CEO.
Suppliers now have to think about international design and manufacturing
locations and meeting faster project schedules with lower costs as automotive
manufacturers cut development cycles.
In the project's first phase, SRI demonstrated a novel
computational approach to help researchers create, analyze, and test
models of complex EGFR signaling networks .

reasoning eades

com.
The ultimate research goal of Pathway Logic is to create models of
large-scale signaling networks in defined cell types -- computational
models of mammalian cells defined in terms of their molecular
responses to specific environmental signals.

theorem eder

CoCreate Demonstrates Support for Microsoft 's Peak Performance Initiative at the Global Automotive Summit

and SINDELFINGEN, Germany,
CoCreate Software, Inc.
CoCreate's OneSpace.

Business Editors/Health/Medical Writers/High-Tech Editors
BIOWIRE2K

MENLO PARK, Calif.com .

conceptual visualization

"Automotive suppliers design more products and components for new vehicles
every year," said William M.
The NIGMS grant provides support for the mathematical modeling of
complex mammalian signaling and other biological networks, using SRI's
unique formal methods tools.

engelbart belief

"Technology solutions companies are taking supply chain planning and
execution to the next level," said Dr.smartops.

temporal engelbart

net Overcomes Challenges of Distributed Design, Increasing
Performance of New Product Development

FORT COLLINS , Colo.

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net collaboration software is for project teams who are
overwhelmed by the complexity of a design process that stretches across sites,
contractors, or outsourced teams.
We help teams design products, manage CAD data, and share ideas so they
can reach their time-to-market goals.

Ultimately, we
intend to make our integrated and interactive online Pathway Logic
tools available to a wide community of biologists and biomedical
researchers.

temporal calculi

"The Peak Performance Initiative is designed to provide a rich
framework to support solutions such as OneSpace."

About CoCreate
CoCreate's flexible CAD and collaborative PLM applications enable
manufacturers to take advantage of changes within their supply chains and
markets. "Many of our customers are adding MIPO to their existing SAP and SAP
APO systems to support a more robust business architecture for supply chain
planning. Based on academic advancements in supply chain modeling and
algorithms , SmartOps' suite of inventory and replenishment optimization
solutions offers companies the ability to improve critical key planning
targets in the presence of multi-stage complexities, inherent supply and
demand uncertainties, and the need for frequent, dynamic decision support.