The results of the study, conducted by Ohio State
University Department of Nutrition, were presented today at the Federation of
American Societies for Experimental Biology (FASEB) annual meeting. Chromium, which
is found naturally in foods in small amounts, is not well absorbed by the
body.com.

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The researchers found that women who consumed chromium supplements absorbed a
significantly higher amount of chromium picolinate, as compared with the other
three types of chromium, based on 24-hour urine content analysis. "Chromax is the most-researched form of chromium . Nutrition 21 holds 36 patents for nutrition
products, 27 of which are for chromium compounds and their uses.

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New Study Shows Chromax(R) Chromium Picolinate is Better Absorbed Than Other Forms of Nutritional Chromium

Researchers tested the subjects' urine, collected over
24 hours after chromium supplementation , to determine how much chromium they
had absorbed.diachrome.

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The data is also significant for healthcare providers in
determining which type of chromium supplement to recommend to patients . These new
findings further support its position as the optimal delivery form for
improved chromium nutrition, a category that is increasingly being recognized
as important for maintaining metabolic health. Such
statements can be identified by lead-in "Looking Forward. Actual results may vary
materially from those in the forward-looking statement.

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Nutrition 21 also
developed Diachrome(R), which is available through diabetes educators or at
http://www. More
information is available at http: //www.

Bactolac Pharmaceutical Inc. Announces Successful Completion of NNFA Certification Audit

Dr. Actual results or developments may differ
materially from those projected in the forward-looking statements as a result
of many factors, including adverse changes in market conditions, fluctuations
in sales volumes and problems in collecting receivables.

NanoSignal Corporation Announces the Acquisition of Santa Rosa Trading Inc. Their Product Line Amazinger Energy Health and Nutritional Line of Drinks

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"Knowing which form of
chromium is best absorbed by the body is important information for consumers
who hope to achieve the optimal health benefits associated with chromium
supplementation ."
Chromium is an essential trace mineral critical to proper insulin function
and necessary for carbohydrate, fat and protein metabolism., Advanced
Nutraceuticals, Inc.

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(1)
Absorption of chromium from chromium chloride was found to be very low and not
much different than baseline. Santa Rosa
Trading seeks to provide optimum nutrition to improve health.

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Data Presented Today at Experimental Biology (FASEB) Conference Support
Chromax as Chromium of Choice for Nutritional Supplements and Foods

SAN DIEGO, (Nutrition 21, Inc.
The study compared absorption of four different types of nutritional
chromium at a dose of 200 mcg, in the form of: Chromax chromium picolinate,
chromium chloride, chromium niacin amino acid chelate and chromium nicotinate.

For additional information contact:
Gregory Pusey (303) 722-4008 (Email: gpusey@gpusey.

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In
addition, understanding which form and what dose of chromium to use in
clinical studies is important to the advancement of chromium research. These data will help
guide manufacturers in selecting a better absorbed form of chromium for use in
their product formulations, so that they can meet the consumer expectation for
delivering product benefits," said Gail Montgomery, president and CEO,
Nutrition 21."

Study Design
The study included 12 young adult women, each assigned to take a single
dose of 200 mcg nutritional chromium.
(2) Ibid

HAUPPAUGE, N." These
statements are not guarantees of future performance and involve
significant risks and uncertainties.

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, has completed and been
formally notified that it has successfully passed the certification audit for
the National Nutritional Foods Association ("NNFA") GMP Third Party
Certification Program. These
statements are based on certain assumptions made based on experience, expected
future developments and other factors the Company believes are appropriate
under the circumstances.

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et al.

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com)

This press release includes "forward looking statements" as defined by the
Securities and Exchange Commission (the "SEC").

Business Editors/Health Editors

LAS VEGAS----NanoSignal Corp. The acquisition
which is a stock transaction was signed on Saturday, March 5, 2005. The Amazinger Energy Drink has the following
nutrition:

196 active natural Compounds

14 Vitamins + 70 Ionic + Colloidal Minerals

7 Herbs + 19 Amino Acids

10 Important Antioxidants

Our Mission + Pledge With Our New Acquisition Subsidiary is to
assist our newly acquired subsidiary Santa Rosa Trading , making it
possible to offer the direct consumer the highest quality energy
drinks and nutritional products in the entire World.

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Chromium chloride is commonly used in multi-
vitamin and mineral formulations for consumption as supplements and is also
widely utilized in vitamin and mineral pre-mixes for food fortification.
"The results indicate that not all forms of chromium are the same," said
lead researcher Robert DiSilvestro, Ph., professor in the Department of
Human Nutrition at Ohio State University in Columbus.org. Such statements are subject to a number of
assumptions, risks and uncertainties , many of which are beyond the control of
the Company.
NanoSignal Corporation is focusing specifically in health treatment in
this acquisition in addition to Slices and its ability for early
detection of strokes and other diseases.

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, an
OTC Pink Sheets Fully Reporting Company (Pink Sheets: NNOS), announced
today that it has acquired Santa Rosa Trading, Inc.

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Chromium chloride
produced a much lower mean urinary value than other preparations.Y. The contents of this release should be considered
in conjunction with the warnings and cautionary statements contained in the
Company's recent filings with the SEC ."

This press release contains "forward-looking statements" within
the meaning of Private Securities Litigation Reform Act of 1995.

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Nutrition 21 is a nutritional bioscience company and the maker of
chromium-based supplements with health benefits substantiated by clinical
research.

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Chromium picolinate gave a considerably higher mean value than the two
nicotinate-based preparations or chromium chloride. (OTC Bulletin Board: ANII) announced that its wholly
owned subsidiary, Bactolac Pharmaceutical , Inc.

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Research suggests that the typical American diet may not provide enough
of this essential mineral.

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The company markets Chromax(R) chromium picolinate, which is the
most-studied form of the essential mineral chromium.

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A large and growing body of clinical studies
indicates that nutritional supplementation with chromium, especially in the
form of chromium picolinate, can improve insulin function and blood sugar
control in people with insulin resistance and type 2 diabetes.

(1) DiSilvestro R. Reddy went on to
explain that as a NNFA certified manufacturer, Bactolac will now be able to
include the GMP Certification disclosure on its products.

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After a washout period of up to two weeks, the women repeated
the sequence three more times, each time with a different form of chromium.(2)

About Nutrition 21, Inc. Pailla Reddy, President of Bactolac.
ANI, through Bactolac, is a private label contract manufacturer of
vitamins and supplements.

, a Tennessee based
company that makes energy drinks dubbed Amazinger.
Amazinger Energy Drink gets the zing from Green Tea, Yerba Mate',
Noni Juice and natural Ginger Root, Ginseng, Sambazon Acai and
Jasmine, Lycopene. Dr Rupert Perrin, chairman of
the board of NanoSignal Corporation , said, "We will have the Dicom
compatibility work hopefully commencing within the next two weeks ,
after which our joint venture partners and engineers might conclude
the Hitachi open end MRI unit at Desert Radiology in Las Vegas Nevada
in another 8-10 weeks.

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A crossover design was used with random
order of administering different types of chromium supplements: Chromax
chromium picolinate, chromium chloride, chromium niacin amino acid chelate and
chromium nicotinate.nutrition21 . NNFA is the leading industry organization promoting
high quality standards and certifying GMP manufacturers .
"Bactolac has spent extensive time and resources in improving its
manufacturing standards and quality processes as a GMP manufacturer and we are
very proud that Bactolac received an 'A' compliance rating upon the NNFA
audit," noted Dr. Bactolac formulates, manufactures, coats and
packages encapsulated and compressed tablets, powder blended vitamins and
related nutritional supplements . All statements, other than
statements of historical fact, included in the press release that address
activities, events or developments that the Company believes or anticipates
will or may occur in the future are forward-looking statements.
The drink, known as Amazinger, is a Maximum Energy Liquid Supplement
and is fortified with a unique blend of natural energizing elements.

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com), or
Jeff McGonegal (303) 475-3786 (Email: jmcgonegal@aol.

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D.
"This study is a significant milestone for Nutrition 21 because it further
distinguishes Chromax from other forms of chromium., Comparison of acute absorption of various
types of chromium supplement complexes, presented at Experimental
Biology 2005, sponsored by FASEB, on April 2, 2005. Additional
information concerning the NNFA can be found on their web site at
http://www. Investors are cautioned that any such statements are not
guarantees of future performance.

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Nasdaq: NXXI) -- A new study shows that Chromax(R) chromium picolinate is
better absorbed by the body than other forms of chromium used as nutritional
supplements and in foods.com.nnfa. Furthermore, the
Company does not intend (and is not obligated) to update publicly any
forward-looking statements.

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