----OSIsoft,
Inc. In addition,
RtPM's events-driven tools leverage Microsoft .

Business Editors
BIOWIRE2K

LARCHMONT, N.

eis agre

It is also designed for fast deployment
and easy integration with any existing IT infrastructures. Using proven Microsoft technology, Digital Pharma
illustrates how drug manufacturers can achieve speed-to-insight and
value-for-cost: two distinct industry imperatives that lead the way
for business transformation.

Genetic Engineering News Reports on Quest for $100 000 Genome

philosophies mulder

Y.genengnews. This is no
simple task because even using current advanced capillary-based DNA
sequencers, it still costs over $10 million to sequence three billion
base pairs, according to the March 1 issue of GEN.
"The holy grail of sequencing human genomic DNA is a cost of
$1,000. "But it's more realistic to shoot for the
$100,000 mark since a number of new technologies might be close to
commercial availability in five years or so.

contributes capturing

Because the RtPM Platform is based on OSIsoft's proven PI System
information architecture, it is designed for high reliability and
massive scalability -- elements that are critical in today's
pharmaceutical environments.

"

About Microsoft's Digital Pharma

Microsoft's Digital Pharma provides a practical vision and
framework that enables pharmaceutical companies to drive innovation
across the enterprise and address strategic value-chain capability
requirements.D.

proprietary workingpapers

The Online Articles category is a directory of
sites that are related to academic scholarships in
Management Information Systems.

mulder workingpapers

, who focuses on single molecule
sequencing by synthesis.

workingpapers restating

Drug makers can quickly analyze
performance of multiple manufacturing paths along with detailed
individual equipment performance . The company is now pursuing single molecule DNA
sequencing using charge switch deoxyribonucleotide triphosphates.com

proprietary contributes

More information can be found at
http://www. OSIsoft and
the OSIsoft logo, the PI System, ActiveView, AlarmView, BatchView,
DataLink, ICE, Module Database, ProcessBook , ProcessPoint, Process
Templates, RtReports and RtPM are trademarks of OSIsoft, Inc.

ingrid jamal

OSIsoft Announces Support for Microsoft Digital Pharma; OSIsoft's RtPM Platform Drives Operational Efficiency and Real -Time Collaboration for Pharmaceutical an

OSIsoft's RtPM Platform leverages Microsoft(R) Windows Server (TM),
the Microsoft Office System, and its Smart Client infrastructure to
help improve life sciences organizations by providing operational
insights to all employees, leading to better, faster, more relevant
decisions and actions throughout the operations cycle. Providing comprehensive visibility into
operations, the OSIsoft platform unlocks the potential for timely
analysis and the ability to make critical, informed and profitable
decisions.
Helicos BioSciences (Cambridge, MA) is working to create a
practical sequencing platform for a technology developed by Stanford
University's Stephen R.

capturing saying

Pharmaceutical and biotechnology organizations have long realized
the need to adopt manufacturing innovations to raise their quality
product standards, improve their compliance obligations and gain
real-time insight into their batch processes to speed time-to-market. Major global pharmaceutical and biotechnology
manufacturers already rely on RtPM to improve the quality of their
manufacturing operations and optimize existing IT investments. "We are delighted to be working with Microsoft on the Digital
Pharma initiative to deliver proven, complimentary technologies that
not only speed effective , critical decision making but offer a lower
total cost of ownership to support industry-wide innovation and
improvement.
Genetic Engineering News is published 21 times a year by Mary Ann
Liebert , Inc.

mulder moises

, the global leader in Real-time Performance Management (RtPM)
software for the process manufacturing industries, today announced its
support of Microsoft Digital Pharma, a vision and solutions framework ,
based on open standards, that will help improve productivity,
integrate disparate data sources , and enable better collaboration
across the pharmaceutical value chain.
However, many have been slow to adopt new technologies due to the
economic pressures and high costs of updating or configuring old
systems while meeting stringent FDA regulations. These proven capabilities enable outstanding
quality and consistency, batch accuracy, regulatory compliance and
cost control.

workingpapers philosophies

NET technology and
Information Worker (IW) platform in a Service Oriented Architecture
(SOA) to deliver unified , role-based portal views of information
across the enterprise.00, which is the target suggested by the U.

agile moises

ingrid dss

Business Editors/Health/Medical Writers/High-Tech Editors

SAN LEANDRO, Calif.
OSIsoft 's flagship RtPM Platform, powered by the PI System, will
be part of the Digital Pharma initiative in response to the growing
demand for instant, critical and actionable operational performance
metrics across pharmaceutical and biotechnology organizations.
"Due to the increase in production errors and the FDA's
demonstrated support of PAT, the life sciences industry must adopt new
manufacturing practices to raise quality standards and improve
inefficiencies," said Michael Saucier, vice president of marketing at
OSIsoft., with operations worldwide and is privately held.

proprietary telemedicine

com/lifesciences

About OSIsoft

OSIsoft delivers performance management software to the world's
leading process manufacturing , life sciences, and utility companies --
anywhere real-time operational metrics fuel performance . With more
than 10,000 installations worldwide, OSIsoft's real-time data platform
crosses IT and process boundaries to incorporate and display
operational information.

saying structuration

com).

mulder dependence

In addition, the RtPM Platform is an
invaluable resource for regulatory compliance, providing full audit
trail capabilities; gathering real-time and historical data from
diverse sources, including events, databases and enterprise systems.microsoft.

----Biotech companies
and academic centers are exploring a variety of techniques to try to
drastically reduce the cost of DNA sequencing to about $100,000.
LI-COR maintains that its methodology, while still under development,
holds advantages over other techniques because there is no limit to
read length except the length of the template.

capturing disadvantage

"With RtPM, OSIsoft helps companies achieve speed-to-insight, one
of the industry imperatives Digital Pharma's vision and solutions
framework seeks to address, as well as easily meet compliance
standards," said Steve Shihadeh, general manager, Microsoft Healthcare
and Life Sciences."
The RtPM Platform provides drug manufacturers with an accurate,
real-time view of the operations environment at any given point
throughout the production cycle.

dss mulder

This allows
life sciences organizations to leverage existing assets and systems
for improved agility, productivity and profitability.

Copyright (C) 2005 OSIsoft, Inc.S. National Human
Genome Research Institute (NHGRI)," notes John Sterling,
Editor -in-Chief of GEN. For a copy of the March 1 issue, please call
914-834-3100, ext.

dependence carla

Founded in 1980 , OSIsoft, Inc.
Other companies covered in the GEN article include Microchip
Biotechnologies (Fremont , CA), Agencourt Bioscience (Beverly, MA), and
454 Life Sciences (Branford, CT).

methodology eis

restating saying

ingrid carla

is headquartered in San Leandro,
Calif."
LI-COR (Lincoln, NE), for example, says that it pioneered the
development of infrared fluorescence labeling and detection systems
for DNA sequencing. Quake, Ph.

restating ingrid

00,
reports Genetic Engineering News (GEN; www. 623, or email: ebicovny@liebertpub.

diaz mulder

Customers will also benefit from RtPM's greater return on existing and
new investments and continuous process improvement. "We are pleased to align with strong partners like
OSIsoft, who have developed valuable industry-specific solutions, and
who really exemplify the Digital Pharma vision. Helicos stresses that moving away from the
Sanger sequencing technology breaks the price and throughput
bottleneck for whole-genome sequencing.