Ms.S.

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"We will continue to build on Jefferies' leading
capabilities in all aspects of the capital markets and as a strategic
advisor focused on middle market companies.
(Nasdaq: MKTX), the operator of a leading electronic trading platform for U.) or 617-801-
9711 (international).S.

About MarketAxess
MarketAxess operates one of the leading platforms for the electronic
trading of corporate bonds and certain other types of fixed-income securities,
serving as an electronic platform through which our more than 500 active
institutional investor clients can access the liquidity provided by our
broker -dealer clients.

Investment Banks advise and process financial transactions for businesses and investors .

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Prior to Jefferies, she spent
nearly 10 years at SG Cowen, where she led that firm's investment
banking in the biotech and emerging pharmaceutical sector.jefco.m.

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Jefferies has six securities traders dedicated to healthcare,
and, with inclusion of its European affiliate, eight senior research
analysts , including four analysts focused on life sciences and four
covering a range of industries within healthcare services. The Webcast will also be archived on
http://www.

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"
"I am delighted to join Jefferies' thriving investment banking
group to help build a strong life sciences practice within this
dynamic organization," said Ms. Grimaldi spent eight years at Goldman Sachs, and has advised
companies in connection with raising public and private equity and
other strategic transactions .

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Grimaldi has joined as a
Managing Director and head of the firm's investment banking effort in
the life sciences area of healthcare.

Typical Investment Bank transactions are IPOs, M

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Business Editors/Health Editors

NEW YORK----Jefferies + Company,
Inc. Headquartered in New York, with more than 20
offices around the world, Jefferies provides clients with capital
markets and financial advisory services, institutional brokerage,
securities research and asset management.

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Grimaldi will focus on
biotech and emerging pharmaceutical companies and lead Jefferies'
efforts in providing them strategic advisory and capital raising
services.com. high-grade corporate bonds, European high -grade
corporate bonds, credit default swaps, agencies, high yield and emerging
markets bonds.

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Grimaldi will be based in Jefferies' New York headquarters
office.

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Ms.

chanen quarterdeck

To access the conference call, please dial 800-299-0148 (U.) or
617-801-6888 (international) for two weeks after the announcement .
MarketAxess' current participating dealers are: ABN AMRO, Banc of America
Securities, Barclays PLC, Bear Stearns, BNP Paribas, Citigroup Global Markets,
Credit Suisse First Boston, Deutsche Bank Securities, DZ Bank, FTN Financial,
Goldman Sachs, HSBC, ING Financial Markets, JP Morgan, Jefferies and Company,
Lehman Brothers, Merrill Lynch, Morgan Stanley, RBC Capital Markets, The Royal
Bank of Scotland, Santander Investment Securities, SG Corporate + Investment
Banking, UBS and Wachovia Securities.

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(NYSE: JEF;
www.com

Rucker, Chief Financial
Officer, will host a conference call to discuss the Company's financial
results and outlook on Tuesday, November 1, 2005 at 8:00 a. The passcode for all callers is 47952730.

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Jefferies Adds Senior Healthcare Banker; Annette Grimaldi to Lead Firm's Investment Banking in Life Sciences

The healthcare sector has long been one of the firm's areas of
focus. Handler, Chairman and CEO
of Jefferies.S.

Through Sales and trading , Research, and Corporate Finance, Investment Banks are the matchmakers between companies that need capital and investors.

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The Company
will also host a live audio Webcast of the conference call on the Investor
Relations section of the Company's website at http://www.

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The firm is a leading
provider of trade execution in equity, high yield, convertible and
international securities for institutional investors and high net
worth individuals. Richard M. MarketAxess' multi-dealer trading platform allows our
institutional investor clients to simultaneously request competitive,
executable bids or offers from multiple broker-dealers, and to execute trades
with the broker-dealer of their choice.

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"
Ms . Previously,
Ms.

About Jefferies

Jefferies, a global investment bank and institutional securities
firm, has served growing and mid-sized companies and their investors
for over 40 years .

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(NYSE:JEF), today announced that Annette C.
"Annette Grimaldi's outstanding experience and deep relationships
in life sciences significantly enhance our strong position in serving
the healthcare sector," commented Richard B.marketaxess.

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NEW YORK, MarketAxess Holdings Inc.marketaxess.com for 90 days following the announcement.

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"Jefferies' focus on growing
and mid-sized companies and the firm's full product offering are well
suited to the life sciences industry. The
passcode for replay callers is 78107350. MarketAxess also provides data and analytical tools that help
our clients make trading decisions, and we facilitate the trading process by
electronically communicating order information between trading counterparties.

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Eastern time.S. An
archive of the call will be made available by dialing 888-286-8010 (U.

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, the principal operating subsidiary of Jefferies Group, Inc.

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Grimaldi. Grimaldi has nearly 18 years experience on Wall Street, the
majority being focused in healthcare. Jefferies + Company, Inc. is the principal
operating subsidiary of Jefferies Group, Inc. McVey,
MarketAxess ' Chairman and CEO, and James N. B.

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MarketAxess to Host Conference Call Announcing 2005 Third Quarter Results

and European high-grade corporate and emerging markets bonds, will announce
its 2005 third quarter results on Tuesday, November 1, 2005.

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She received a Masters in Business
Administration and a Masters in International Studies from The Wharton
School at the University of Pennsylvania , and a Bachelor of Science in
Foreign Services degree from Georgetown University.

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MarketAxess offers our clients the
ability to trade U.

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---

- - kjjkjk

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