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Central European Media Enterprises Receives Approval To Begin Trading on the Prague Stock Exchange

The listing particulars are intended to be
published Wednesday, June 22, 2005.

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United Therapeutics Completes European Mutual Recognition for Remodulin(R)

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France was the Reference Member State for the MRP as France was the first
European Union nation to approve Remodulin in February 2005.

(CME) is a TV broadcasting company
with leading stations in six Central and Eastern European countries reaching
an aggregate of approximately 90 million people.

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, Vice President of
Regulatory Affairs for United Therapeutics. JPMorgan
provided advisory services to CME.
Tel: +1-212-986-6667

United Kingdom:
Wallace Macmillan (Investors)
Vice President Finance + Chief Financial Officer
Tel: +44-20-7430-5430

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Rothblatt.
"We are pleased to have received national approvals in 22 additional
countries of the European Union," said Dean Bunce, Sr .0006).

In addition to historical information, this press release contains
forward-looking statements about expectations regarding the commencement of
commercial sales and marketing activities of Remodulin in Europe, the timing
of the receipt of the formal action letters and pricing approvals , the
resubmission of Remodulin marketing authorization applications in Ireland,
Spain and the United Kingdom and discussions with regulators in these three
countries that are based on United Therapeutics' current beliefs and
expectations as to future outcomes.

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and RESEARCH TRIANGLE PARK , N.
Specifically, 13 of 14 patients (93%) in the Remodulin arm were able to
successfully transition from Flolan and complete the study without the need to
institute rescue therapy, compared to only 1 of 7 patients (14%) in the
placebo arm. CME shares are expected to begin
trading on the PSE on Monday, June 27, 2005 and to become a part of both major
PSE indices PX50 and PX-D as of July 1, 2005.com or
contact:

United States:
Jonathan Lesko/ Michael Smargiassi (Investors )
Olga Shmuklyer (Press)
Brainerd Communicators, Inc.

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D. Applications in Ireland, Spain and the United
Kingdom were withdrawn by United Therapeutics with regulatory discussions
underway concerning the timing of resubmission in these three countries.
There can be no assurances as to the timing of the receipt of the formal
action letters and pricing approvals and the completion of discussions and
resubmissions in the remaining three countries.

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, United Therapeutics' Chairman and CEO."
On August 2, 2005, United Therapeutics announced that the results of the
interim assessment from the Phase IV trial were positive (p = 0. These expectations are subject to risks
and uncertainties such as those described in United Therapeutics' periodic
reports filed with the Securities and Exchange Commission which may cause
actual results to differ materially from anticipated results. ("CME") (Nasdaq: CETV) announced today that the Czech
Securities Commission has approved the listing particulars prepared in
connection with the listing of its Class A Common Shares on the Main Market of
the Prague Stock Exchange (PSE).

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Remodulin to be Approved in 22 Additional European Union Countries
with Resubmissions to be made in Three Countries

SILVER SPRING, Md.
"Our pursuit of the European approvals and resubmissions demonstrates our
commitment to making Remodulin available as widely as practical," said Martine
Rothblatt, Ph. "Refilings in Ireland, Spain and
the United Kingdom will be bolstered by interim data from the United States
Phase IV Flolan (R) transition trial. CME will trade on the PSE under
the ticker symbol CETV.

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, United Therapeutics Corporation (Nasdaq: UTHR)
announced today that the European Union Mutual Recognition Procedure (MRP) has
been completed for Remodulin (treprostinil sodium) Injection for the
subcutaneous treatment of NYHA Class III Primary Pulmonary Hypertension
patients. Consequently,
such forward-looking statements are qualified by the cautionary statements,
cautionary language and risk factors set forth in United Therapeutics'
periodic reports and documents filed with the Securities and Exchange
Commission , including the company's most recent Form 10-K and Form 10-Q.

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Ceska sporitelna is the local listing agent.

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"We appreciate the
opportunity to work with the European authorities on subcutaneous Remodulin
currently, on intravenous Remodulin in the near-term and, subject to the
outcome of pending studies , on inhaled and oral formulations as well,"
concluded Dr. (Remodulin
currently is reimbursed in a number of European countries on a non-marketed
individual patient basis). The Listing Committee of the PSE approved
the CME listing on Friday, June 17, 2005.

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For additional information , please visit http://www.

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United Therapeutics is a biotechnology company focused on the development
and commercialization of unique products for patients with chronic and life-
threatening cardiovascular , cancer and infectious diseases. HAMILTON, Bermuda, Central European
Media Enterprises Ltd.

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At the
completion of the MRP, the following countries endorsed the mutually-agreed
summary of product characteristics for Remodulin: Austria, Belgium, Czech
Republic, Cyprus, Denmark, Estonia , Finland, France, Germany, Greece, Hungary,
Iceland, Italy, Latvia, Lithuania, Luxembourg, Netherlands , Norway, Poland,
Portugal, Slovakia, Slovenia, and Sweden. With French approval already
completed , formal action letters must be issued by the 22 other countries and
pricing approvals must be issued by each country before commercial sales and
marketing activities for Remodulin may commence in each country.

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CME is traded on the Nasdaq under the ticker symbol
"CETV".

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We look forward to presenting complete
Remodulin data to regulators in these three European nations.
United Therapeutics is providing this information as of August 10, 2005 and
undertakes no obligation to publicly update or revise the information
contained in this press release whether as a result of new information , future
events or any other reason.

Central European Media Enterprises Ltd. The Company 's television
stations are located in Croatia (Nova TV), Czech Republic (TV Nova), Romania
(PRO TV, Acasa, PRO Cinema), Slovakia (Markiza), Slovenia (POP TV, Kanal A)
and Ukraine (Studio 1+1).

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cetv-net.