, EntreMed, Inc. Students work at home with a parent
or responsible adult and receive instruction and guidance from certified
public school teachers who operate remotely .C.com.org.

american presents

CONTACT:
James Moore
EntreMed Communications
+1-202-258-0776

Students who enroll receive a
computer, monitor, printer, access to the K12 Online School , lessons,
assessments, books, materials, planning and progress tools, and much more. The learning program
was developed by a team of education experts who meticulously developed the
curriculum by researching and identifying the best learning methods and
material.
More than 20,000 students nationwide are currently using the K12
curriculum and learning program in a variety of learning environments ,
including traditional schools and classrooms, virtual (online) schools, and
private homeschools .K12. More information on the Arkansas
Virtual School can be found at http://www.

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Additionally , the compound has been shown to be an
inhibitor of inflammation in preclinical rheumatoid arthritis and acute
inflammation models. Antagonists of PAR-2 signaling demonstrate a potential
relationship between the onset of inflammation and the regulation of tumor
growth and angiogenesis. All intellectual property associated with the PAR-2
peptide and small molecule mimetics are owned exclusively by EntreMed . Forward-looking statements are subject to
numerous assumptions, risks and uncertainties, which change over time.
Forward-looking statements speak only as of the date they are made, and
EntreMed assumes no duty to update forward-looking statements. Levi has been enrolled in ARVS for the past two
years . In his first year at the national
level he finished fifth; this year he finished third in the nation and won a
$10,000 college scholarship. K12's comprehensive curriculum is based on traditional subjects and
core skills.

photograph k

EntreMed's goal
is to develop and commercialize new compounds based on the Company 's expertise
in angiogenesis, cell cycle regulation and inflammation -- processes vital to
the treatment of cancer and other diseases. because it will
allow him to visit a lot of the places that he has learned about through the
K12 program.

About the Florida Virtual Academy (FLVA ):
The Florida Virtual Academy is a statewide public virtual school pilot
program through the Florida Department of Education.

photograph biography

Forward-looking statements are typically identified by words or phrases
such as "believe," "feel," "expect," "anticipate," "intend," "outlook,"
"estimate," "target," "assume," "goal," "objective," "plan," "remain," "seek,"
"trend," and variations of such words and similar expressions, or future or
conditional verbs such as "will," "would," "should," "could," "might," "can,"
"may," or similar expressions.
K12 Inc.

Levi Foster: Arkansas Virtual School eighth grade student
Levi Foster and his four siblings all use the K12 program as students in
the Arkansas Virtual School. He is fascinated with language, literature, and, along with his
grandfather, shares a love for words. Sam's favorite
subject in the K12 curriculum is history .

About K12 Inc. ARVS uses the high
quality K12 curriculum and learning program.

kizer literature

Additional information about EntreMed is available on
the Company's website at http://www. is proud of Levi and Sam for their outstanding achievements. The
entire K12 family extends our best wishes to both of them as they compete in
this year's National Spelling Bee.

About the Arkansas Virtual School (ARVS):
The Arkansas Virtual School is a statewide public virtual school pilot
program of the Arkansas Department of Education funded by the U.org.

biography poems

(Logo: http://www. Results of the Company's preclinical studies indicate that its
PAR-2 antagonist inhibits both tumor growth and the formation of new blood
vessels in cancer models.
Levi won the Arkansas State Championship for the Reader's Digest National
Word Power Challenge the past three years.
"I really like the text books by Joy Hakim and I find it interesting to
read about the past, especially American history," he says.

kizer poems

EntreMed Presents Progress on PAR-2 Program in Oncology and Inflammation

Carolyn F. We are conducting further studies to understand PAR-2's mechanisms-
of-action, identify additional small molecule PAR-2 antagonists, and determine
the potential applications for PAR-2 in oncology and inflammatory diseases. Among
the spellers will be two eighth grade boys who are students in an exciting new
education model that is gaining popularity with many families across the
country -- public virtual schools that use the high quality K12 curriculum and
learning program. It has always been Levi's goal to make it to the
Scripps National Spelling Bee. FLVA uses the nationally
acclaimed K12 curriculum and learning program.

carolyn k

(Nasdaq: ENMD) is a clinical-stage pharmaceutical company
developing therapeutic candidates primarily for the treatment of cancer and
inflammation. EntreMed is
developing these potential drug candidates for either in-house advancement or
external partnering.

Two K12 Virtual Academy Students Participate in Scripps National Spelling Bee Competition in Washington DC

Levi , who enjoys writing his own poetry, has been an avid reader since
age three. "Studying history
is like reading a good story book that just keeps on going.
K12 Inc.arvs.flva.

photograph k

"

About EntreMed
EntreMed, Inc.
Public virtual schools that use the K12 program offer families an
innovative education option that includes a rigorous and comprehensive
curriculum in six traditional subjects. Levi also won his county's spelling bee four
years in a row. His younger brother will be starting
second grade in FLVA in the fall.S. The school serves hundreds of
students across Florida in grades K-8.

american authors

(Nasdaq: ENMD), a clinical-stage pharmaceutical company developing
therapeutics for the treatment of cancer and inflammatory diseases, today
announced the presentation of preclinical research results for its Proteinase
Activated Receptor (PAR-2) Inhibitor program.
The PAR -2 program is part of an integrated EntreMed development effort,
which is focused on a new generation of multi-mechanism drugs for the
treatment of cancer and inflammatory diseases that attack disease cells
directly and the blood vessels that nourish them. Sidor, MD, EntreMed Vice President and Chief Medical Officer,
commented on the presentation, "The PAR-2 program is a key component of our
pipeline .
The New York Academy of Sciences' symposium provided an opportunity to bring
leading PAR-2 scientists together from industry and academia to discuss this
rapidly evolving area of drug development.com and in various filings with
the Securities and Exchange Commission.
Levi Foster of Fayetteville , AR, an eighth grade student in the Arkansas
Virtual School (ARVS), and Sam Lawson of Naples, FL , an eighth grade student
in the Florida Virtual Academy (FLVA), will both compete for the first time in
the Scripps National Spelling Bee.

Sam Lawson: Florida Virtual Academy eighth grade student
Sam Lawson has been using the K12 program as a student in the Florida
Virtual Academy for the past two years.

poems carolyn

The results were presented
yesterday during the New York Academy of Sciences conference on Protease
Activated Receptor (PAR)-2: Understanding the Links Between Protease
Activation and Disease.newscom. Panzem(R) (2-Methoxyestradiol or 2ME2), the Company's lead drug
candidate, is currently in clinical trials for advanced cancer, as well as in
preclinical development for indications outside of oncology. The Company's expertise has also
led to the discovery of new molecules, including analogs of 2ME2, peptides of
tissue factor pathway inhibitor (TFPI), and inhibitors of fibroblast growth
factor-2 (FGF-2) and proteinase activated receptor-2 (PAR-2). Eighth Graders Levi Foster and Sam Lawson Are Students in Public Virtual
Schools That Use the K12 Curriculum and Learning Program

WASHINGTON, On Wednesday and Thursday of this week,
many of the nation 's brightest young kids will gather in Washington, DC to
compete in the prestigious Scripps National Spelling Bee competition. The K12 program
provides every child the tools, attention, and resources needed to ensure they
are receiving the highest quality education.
Sam qualified for the National Spelling Bee by recently coming in first
place in the Collier County Scripps Howard Spelling Bee ."
Sam is excited to compete for the first time in the Scripps National
Spelling Bee.

kizer poets

com/cgi -bin/prnh/20010620/ENMDLOGO )
PAR-2 is a cell surface receptor that is known to play a critical role in
mediating acute and chronic inflammation. EntreMed is developing a peptide
that blocks PAR-2 activity, the first such compound identified as a PAR-2
antagonist.entremed.

Forward Looking Statements
This release contains, and other statements that EntreMed may make may
contain , forward-looking statements within the meaning of the Private
Securities Litigation Reform Act with respect to the outlook for expectations
for future financial or business performance, strategies , expectations and
goals. provides its high quality curriculum and learning program to many
public virtual schools (also known as "online" or "cyber" schools) across the
country, including the Arkansas Virtual School and the Florida Virtual
Academy. Department
of Education's Voluntary Public School Choice Program. The school serves
hundreds of students across Arkansas in grades K-8. More information on the Florida
Virtual Academy can be found at http://www.

authors kizer

PAR-2 Antagonist Inhibits Angiogenesis and Inflammation

ROCKVILLE, Md. EntreMed's product
candidates target multiple disease pathways, including angiogenesis,
inflammation, cell cycle regulation and apoptosis (programmed cell death). Actual results
could differ materially from those currently anticipated due to a number of
factors, including those set forth in EntreMed's Securities and Exchange
Commission filings under "Risk Factors," including risks relating to
EntreMed's need for additional capital and the uncertainty of additional
funding; the early-stage products under development; uncertainties relating to
clinical trials; our success in the further clinical development of Panzem(R)
NCD, dependence on third parties; future capital needs; and risks relating to
the commercialization, if any, of the Company's proposed products (such as
marketing, safety, regulatory, patent, product liability, supply, competition
and other risks).
K12 Inc.
More and more parents are choosing to enroll their children in public
virtual schools that use K12 program because it provides them an opportunity
to be active participants in their child's education. At the Arkansas State Spelling Bee he placed fifth as a fifth
grader, was runner-up in both his sixth and seventh grade years, and won the
competition this year. He is also excited to visit Washington D. is an education company that has developed a comprehensive
learning program including curriculum, tools, materials and an innovative
lesson delivery system through the K12 Online School. More information on K12 can be found at
http://www.

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